METTLER TOLEDO ME104E Advanced Analytical Balance (0.1 mg Readability)
| Brand | METTLER TOLEDO |
|---|---|
| Origin | Shanghai, China |
| Model | ME104E |
| Maximum Capacity | 120 g |
| Readability | 0.1 mg |
| Repeatability | 0.1 mg |
| Linearity | ±0.2 mg |
| Stabilization Time (typical) | 2 s |
| Sensitivity to Temperature Drift | 2.0 ppm/°C |
| Pan Diameter | Ø90 mm |
| Net Weight | 4.5–4.7 kg |
| Calibration | Internal (one-key auto-calibration) |
| Built-in Applications | 10 (e.g., formulation, counting, density, % weighing, checkweighing, statistics) |
Overview
The METTLER TOLEDO ME104E is a high-precision analytical balance engineered for routine laboratory weighing tasks requiring 0.1 mg readability and long-term metrological reliability. Based on METTLER TOLEDO’s NewClassic ME platform, it employs electromagnetic force compensation (EMFC) technology — the industry-standard principle for analytical balances — to deliver stable, drift-resistant measurements under variable ambient conditions. Designed as a direct functional replacement for legacy AL104 and AL104-IC models, the ME104E integrates an internal calibration mechanism activated via single-button operation, eliminating dependency on external weights and reducing procedural variability. Its robust metal frame, reinforced overload protection (rated up to 100 kg mechanical shock resistance), and optimized thermal mass distribution ensure consistent performance across typical lab environments (20–25 °C, 40–60% RH). The balance complies with international weighing standards including OIML R76, ISO 9001, and supports traceable documentation per ISO/IEC 17025 and GLP requirements.
Key Features
- Electromagnetic force compensation sensor with 0.1 mg readability and ≤0.1 mg repeatability (under controlled conditions)
- One-touch internal calibration with temperature-compensated reference mass; no manual weight handling required
- Ergonomic design: front-access leveling feet, rounded edges, smooth stainless-steel pan surface (Ø90 mm), and spill-resistant keypad
- Stabilization time of ≤2 seconds for routine 120 g loads — optimized for throughput in QC, R&D, and teaching labs
- Integrated overload protection and rigid aluminum-magnesium alloy housing for mechanical durability and vibration damping
- Real-time environmental monitoring: built-in temperature drift compensation (2.0 ppm/°C sensitivity)
- ISO/GLP-compliant data output: automatic timestamping (date + time) on all printed or exported results
Sample Compatibility & Compliance
The ME104E accommodates standard analytical sample containers (crucibles, weighing boats, vials) and is routinely deployed in applications involving powders, granules, lyophilized solids, and small-volume liquid aliquots. Its draft shield (sold separately, compatible with standard NewClassic enclosures) meets ISO 17025 environmental control recommendations for microgram-level work. The balance conforms to regulatory frameworks governing quality-critical operations: it supports audit-ready recordkeeping per FDA 21 CFR Part 11 when paired with METTLER TOLEDO LabX Lite software (via RS232/USB interface), and its calibration history, user logs, and result metadata are fully exportable in CSV or PDF format. CE marking, RoHS compliance, and IP42-rated enclosure protection are factory-certified.
Software & Data Management
While the ME104E operates autonomously via its intuitive 4.3-inch monochrome graphic display and function-key interface, it natively supports bidirectional communication via RS232 and USB virtual COM port. This enables seamless integration with METTLER TOLEDO’s LabX Lite — a free, lightweight PC application that automates data capture, enforces SOP-driven workflows, and generates compliant reports with electronic signatures. All measurement events (including calibration, zeroing, and tare actions) are logged with user ID, timestamp, and instrument serial number — satisfying GLP/GMP data integrity requirements. Raw data export preserves full metadata, including stabilization status flags and environmental sensor readings where available.
Applications
- Quantitative formulation and recipe preparation in pharmaceutical development
- High-accuracy sample preparation for HPLC, ICP-MS, and elemental analysis
- Counting small components (e.g., tablets, microfilters, PCB parts) with statistical validation
- Density determination of solids using Archimedean principle (with optional density kit)
- Checkweighing against defined upper/lower tolerance limits in production QA
- Statistical process control (SPC) via batch weighing and deviation reporting
- Teaching laboratories: principles of mass metrology, uncertainty propagation, and calibration hierarchy
FAQ
Does the ME104E require external calibration weights?
No — it features a motorized internal calibration mass and performs full-range verification at the press of a button.
Is the balance suitable for use in a fume hood?
Yes, provided the draft shield is installed and airflow is stabilized below 0.2 m/s at the pan level; consult METTLER TOLEDO Application Note AN138 for installation guidelines.
Can measurement data be exported directly to Excel?
Yes — via USB or RS232 connection using LabX Lite or generic terminal emulation software; CSV output includes all metadata fields.
What is the recommended recalibration frequency?
Per ISO/IEC 17025:2017, recalibration intervals must be risk-assessed; METTLER TOLEDO recommends daily internal verification and formal external calibration every 3–6 months depending on usage intensity and criticality.
Does the ME104E support multi-language interfaces?
Yes — firmware supports English, German, French, Spanish, Chinese, Japanese, and Korean; language selection is configurable via setup menu.
