METTLER TOLEDO MX105/A Advanced Analytical Balance
| Brand | METTLER TOLEDO |
|---|---|
| Origin | Shanghai, China |
| Manufacturer Type | Authorized Distributor |
| Product Category | Domestic |
| Model | MX105/A |
| Instrument Type | Analytical Balance |
| Maximum Capacity | 120 g |
| Readability | 0.01 mg |
| Calibration Method | Internal (FACT) |
| Repeatability (typ.) | 0.0125 mg |
| Minimum Weight (U=1%, k=2, typ.) | 2.5 mg |
| Stabilization Time | 2 s |
| Display | 7-inch color TFT touchscreen |
| Pan Diameter | 80 mm |
| Dimensions (H×W×D) | 353 × 222 × 379 mm |
| Connectivity | USB-A, USB-C, Ethernet (LAN), Bluetooth (optional) |
| Compliance | USP <41>, <1251>, GxP-ready, 21 CFR Part 11 compatible (with optional software and audit trail configuration) |
Overview
The METTLER TOLEDO MX105/A is a high-performance analytical balance engineered for precision mass measurement in regulated laboratory environments. Utilizing electromagnetic force compensation (EMFC) technology, it delivers traceable, reproducible results with a readability of 0.01 mg and maximum capacity of 120 g. Designed for applications demanding strict adherence to pharmacopeial and regulatory standards—including USP (Weights and Measures), USP (Weighing on an Analytical Balance), and ISO/IEC 17025—the MX105/A integrates metrological rigor with intuitive operation. Its core architecture supports GLP/GMP workflows through built-in audit trail capabilities, user-level access control, and automated data capture—ensuring full traceability from weighing event to final report.
Key Features
- SmartPan™ Weighing Pan: Patented asymmetric pan design minimizes air turbulence effects, reducing stabilization time to ≤2 seconds—even under non-ideal draft conditions—without compromising repeatability (typ. 0.0125 mg).
- Internal Calibration (FACT): Fully automatic temperature-controlled calibration system maintains accuracy across ambient fluctuations (±1.5 °C), eliminating manual recalibration drift.
- ErgoDoor™ Draft Shield: Motorized, low-profile sliding doors with soft-stop mechanism reduce operator fatigue and improve workflow ergonomics during repetitive weighing tasks.
- 7-inch Full-Color TFT Touchscreen: High-resolution interface with customizable home screen, multilingual support (EN/DE/FR/ES/ZH/JP/KO), and gesture-based navigation for rapid method execution.
- Energy-Saving Mode: Adaptive power management reduces standby consumption by up to 70% while preserving readiness for immediate measurement.
- GxP-Ready Architecture: Supports role-based user management (up to 100 users), electronic signatures, and configurable audit trail logging compliant with FDA 21 CFR Part 11 when paired with LabX™ software.
Sample Compatibility & Compliance
The MX105/A accommodates standard sample containers (vials, crucibles, weighing boats) via its 80 mm diameter stainless-steel pan. Its minimum weight threshold—2.5 mg (k=2, U=1%) and 25 mg (USP , ±0.1% tolerance)—is validated per ISO 14412 and documented in the integrated calibration certificate. The balance meets OIML R76-1 Class I requirements for legal-for-trade use in select jurisdictions and is certified to EN 14372 for child-resistant packaging testing. All firmware updates are version-controlled and traceable; calibration records include timestamp, operator ID, environmental conditions (T/ RH), and uncertainty budget per EURAMET cg-18.
Software & Data Management
Native connectivity includes USB-A (for printers and flash drives), USB-C (for direct PC tethering), and Gigabit Ethernet for network integration into LIMS or ELN systems. Optional Bluetooth enables wireless pairing with mobile devices for remote status monitoring. When deployed with METTLER TOLEDO LabX™ software, the MX105/A supports fully automated workflows—including SOP-guided weighing, real-time statistical process control (SPC), and electronic batch record generation. Audit trails are encrypted, tamper-evident, and exportable in PDF/A-1b or CSV format—with full compliance to ALCOA+ principles (Attributable, Legible, Contemporaneous, Original, Accurate, Complete, Consistent, Enduring, Available).
Applications
The MX105/A is routinely deployed in pharmaceutical QC laboratories for active pharmaceutical ingredient (API) assay, reference standard preparation, and dissolution tablet weight uniformity testing. It serves analytical chemistry labs conducting gravimetric titration, Karl Fischer water content determination, and catalyst loading verification. In academic research, it supports nanomaterial synthesis (e.g., precise precursor dosing), isotope ratio sample preparation, and microgravimetric corrosion studies. Its robust mechanical design and factory-installed vibration isolation make it suitable for installation on standard lab benches—no dedicated anti-vibration table required.
FAQ
What is the minimum weight requirement for USP-compliant weighing?
Per USP , the minimum weight is defined as the smallest mass that can be weighed with a relative standard deviation ≤0.1%. For the MX105/A, this is 25 mg under typical lab conditions (20–25 °C, <60% RH).
Does the MX105/A support 21 CFR Part 11 compliance?
Yes—when operated with LabX™ software configured with electronic signatures, audit trail, and role-based permissions, it fulfills Part 11 requirements for electronic records and signatures.
Can the balance be integrated into a centralized lab network?
Yes—via Ethernet (TCP/IP), it supports seamless integration with LIMS, MES, or ERP systems using standard protocols including HL7, ASTM E1384, and OPC UA.
Is external calibration required after FACT internal calibration?
Internal FACT calibration ensures daily stability; however, periodic external verification using accredited weights (e.g., class E2 or better) is recommended per ISO/IEC 17025 clause 6.5.2 and manufacturer guidelines.
What environmental conditions affect performance?
Optimal operation requires ambient temperature stability (±1.5 °C/hour), humidity 1 mT.
