Millipore RiOs-DI 3 UV Water Purification System
| Brand | Millipore |
|---|---|
| Origin | France |
| Model | RiOs-DI 3 UV |
| Production Capacity | 10 L/day |
| Resistivity | >10 MΩ·cm (at 25 °C) |
| TOC | <50 ppb |
| Flow Rate | >2.4 L/h (at 15 °C) |
| Internal Reservoir | 6 L |
| Dimensions (H×W×D) | 50 × 29 × 33 cm |
| Operating Weight | 7.3 kg |
Overview
The Millipore RiOs-DI 3 UV Water Purification System is a compact, integrated benchtop solution engineered to produce Type II analytical-grade pure water directly from municipal tap water. Utilizing a sequential purification architecture—comprising pre-filtration, reverse osmosis (RO), and mixed-bed ion exchange—the system delivers consistent water quality meeting ISO 3696 Grade 2 and ASTM D1193 Type II specifications. A built-in 185/254 nm dual-wavelength UV lamp provides continuous photo-oxidation of organic contaminants and microbial inactivation, ensuring low total organic carbon (<50 ppb) and minimized bacterial load (<1 CFU/mL). Designed for laboratories with moderate daily demand (5–10 L), the RiOs-DI 3 UV operates autonomously with an internal 6 L reservoir, eliminating dependency on external storage tanks while maintaining stable pressure and temperature-independent performance via an integrated feed pump.
Key Features
- Integrated RO + deionization architecture delivering resistivity >10 MΩ·cm at 25 °C and TOC <50 ppb—verified per ISO 8573-1 and USP guidelines
- Dual-wavelength UV chamber (185 nm for TOC oxidation; 254 nm for germicidal action) compliant with ISO 14644-1 Class 5 cleanroom requirements for water handling
- Single-use, all-in-one purification cartridge containing sediment pre-filter, thin-film composite RO membrane, and high-capacity mixed-bed resin—reducing cross-contamination risk and simplifying qualification
- Backlit color LCD interface displaying real-time resistivity (MΩ·cm), water temperature (°C), reservoir level (%), and cartridge service life estimation
- Feed pump ensures constant inlet pressure (0.1–0.4 MPa) and flow stability across variable municipal supply conditions—eliminating fluctuations caused by diurnal pressure or seasonal temperature shifts
- Compact footprint (50 × 29 × 33 cm) and lightweight design (7.3 kg) suitable for space-constrained fume hoods, biosafety cabinets, or shared instrumentation benches
Sample Compatibility & Compliance
The RiOs-DI 3 UV is validated for use as feedwater for downstream ultra-pure water systems—including Milli-Q® and Synergy® platforms—as specified in Millipore’s system integration white papers (Ref. PUB-001284-EN). Its output meets the inlet water specifications defined in ISO 14644-1 Annex B for pharmaceutical water pretreatment and satisfies the feedwater criteria outlined in USP “Water for Pharmaceutical Purposes” for subsequent distillation or electrodeionization stages. All wetted components comply with FDA 21 CFR 177.2600 (food-contact polymers) and EU Regulation (EC) No 1935/2004. The system supports GLP/GMP documentation workflows through optional audit-trail-enabled software modules compatible with LIMS integration.
Software & Data Management
While the RiOs-DI 3 UV operates as a standalone unit without network connectivity, its embedded firmware logs operational parameters—including cumulative volume dispensed, UV lamp runtime, and resistivity trend history—for up to 30 days. Data export is supported via USB port (FAT32 format) for CSV-based traceability in quality records. Optional Millipore Connect™ firmware upgrade enables remote monitoring via Ethernet, time-stamped event logging (e.g., cartridge replacement, alarm triggers), and alignment with 21 CFR Part 11 electronic record requirements when deployed with validated user access controls and digital signature protocols.
Applications
- Preparation of buffers, cell culture media, and HPLC mobile phases requiring Type II water per ISO 3696
- Routine glassware rinsing and equipment cleaning where particulate-free, low-ion-content water reduces residue formation
- Feedwater source for Milli-Q® IQ 7000, Synergy® UV, or other point-of-use ultrapure systems—reducing membrane fouling and extending DI cartridge lifetime
- Supporting ASTM E2912-20 (Standard Guide for Water Quality in Laboratories) compliance for non-critical analytical procedures
- Environmental testing labs performing EPA Method 1600-series analyses where background conductivity must remain below 1.0 µS/cm
FAQ
What is the recommended replacement interval for the all-in-one purification cartridge?
Cartridge lifespan is usage-dependent but typically ranges from 6–12 months under average lab conditions (5–8 L/day); the system alerts users at 90% depletion based on resistivity decay and volume throughput.
Can the RiOs-DI 3 UV be connected to a central distribution loop?
No—it is designed exclusively for direct point-of-use dispensing; for loop-fed applications, consider the Millipore Elix® Advantage series with dedicated loop pump and recirculation control.
Does the UV lamp require periodic recalibration or intensity verification?
The lamp operates at fixed output; however, annual verification of UV transmittance (UVT) at 254 nm using a NIST-traceable radiometer is recommended per ISO/IEC 17025 calibration schedules.
Is the system compatible with hard water sources (>200 ppm CaCO₃)?
Yes—the integrated pre-filter and RO stage tolerate inlet hardness up to 400 ppm; however, feedwater with >300 ppm requires optional antiscalant dosing or pretreatment to prevent membrane scaling.
How does the feed pump contribute to water quality consistency?
By maintaining constant 0.2 MPa inlet pressure regardless of municipal supply variation, the pump ensures uniform RO flux and stable ion rejection—critical for reproducible resistivity across diurnal and seasonal supply changes.
