Organomation N-EVAP Series Nitrogen Evaporator
| Brand | Organomation |
|---|---|
| Origin | USA |
| Model | N-EVAP |
| Heating Method | Water Bath |
| Temperature Control Range | Ambient to 90 °C |
| Temperature Uniformity | ±2 °C (6–24 positions), ±0.5 °C (34 & 45 positions) |
| Sample Capacity | 6–45 positions |
| Tube Diameter Compatibility | 10–29 mm (standard), up to 56 mm (optional) |
| Gas Flow Rate | 0–10 L/min (6/12/24), 0–20 L/min (34), 0–30 L/min (45) |
| Input Gas Pressure | 30–150 psig |
| Output Gas Pressure | 0–30 psig |
| Nitrogen Consumption | ~330 mL/min per sample |
| Heating Power | 500–1400 W |
| Construction | Laboratory-grade stainless steel |
| Optional Configurations | Acid-resistant coating (RT), Dry-Block with aluminum beads (DA), PTFE-coated needles (T), Extended 6-inch needles (6), Pasteur pipette adapter (P), Heater-free configuration (O) |
Overview
The Organomation N-EVAP Series Nitrogen Evaporator is a precision-engineered sample concentration system designed for reproducible, low-temperature solvent removal in analytical laboratories. Operating on the principle of inert gas displacement—where dry, filtered nitrogen is directed tangentially across the surface of heated liquid samples—the N-EVAP accelerates evaporation while minimizing analyte degradation, oxidation, and cross-contamination. Unlike vacuum-based concentrators, this system maintains atmospheric pressure and avoids foaming or bumping, making it especially suitable for thermally labile compounds, volatile organics, and multi-analyte workflows common in LC-MS, GC-MS, environmental residue analysis, and clinical toxicology. All N-EVAP models are manufactured in the United States under strict ISO-compliant quality control protocols and comply with general laboratory safety standards including UL 61010-1 and IEC 61000-6-3 for electromagnetic compatibility.
Key Features
- Modular design available in five standard configurations: 6-, 12-, 24-, 34-, and 45-position formats—each optimized for footprint efficiency and ergonomic access within fume hoods.
- Rotating circular sample support allows full frontal access to all tubes without repositioning; each position is laser-engraved with numeric identification for traceable sample tracking.
- Individually adjustable gas delivery needles (stainless steel, 19-gauge, 4″ standard; optional 6″ or PTFE-coated variants) maintain precise height alignment over tube rims—critical for consistent gas shear force and minimal splashing.
- Dual-mode heating options: water bath (ambient to 90 °C, ±2 °C uniformity for smaller units; ±0.5 °C for larger digital-controlled units) or dry-block variants with aluminum bead thermal mass (0–130 °C, optional DA accessory).
- Independent needle valve control at every position enables method-specific flow tuning—essential for heterogeneous sample sets containing solvents with varying volatility and surface tension.
- Gas distribution manifold rated for 30–150 psig inlet pressure, delivering regulated output (0–30 psig) via integrated pressure regulators and calibrated rotameters (0–10 / 20 / 30 L/min range depending on model).
- All wetted and structural components constructed from electropolished 304 stainless steel; optional RT acid-resistant coating (epoxy-polyester hybrid) available for use with HCl, HF, or perchloric acid vapors.
Sample Compatibility & Compliance
The N-EVAP accommodates a broad range of container geometries—including round-bottom test tubes (10–29 mm OD), conical centrifuge tubes, scintillation vials, and culture tubes—with optional adapters supporting diameters up to 75 mm. Liquid volumes per vessel range from 1 mL to 50 mL, ensuring compatibility with micro-scale extractions and preparative workflows alike. The system meets general requirements for Good Laboratory Practice (GLP) environments: temperature stability is documented per ASTM E2208, gas flow calibration adheres to ISO 5167 principles, and mechanical construction supports routine cleaning validation per USP . While not inherently 21 CFR Part 11 compliant, the N-EVAP integrates seamlessly with validated LIMS and electronic lab notebook (ELN) platforms when paired with external data loggers or programmable controllers.
Software & Data Management
The N-EVAP operates as a standalone analog/digital hybrid instrument. Base models feature mechanical thermostats and manual flow control; higher-capacity units (34- and 45-position) incorporate digital PID temperature controllers with LED display, setpoint memory, and over-temperature cutoff (hardware-based thermal limiter). No proprietary software is required for operation. However, third-party data acquisition systems (e.g., LabVIEW, MATLAB, or PLC-based SCADA) can interface via 4–20 mA or 0–10 V analog outputs (available upon request). Audit trails for temperature and gas pressure are maintained manually per SOP or digitally when connected to compliant environmental monitoring systems—supporting regulatory inspections in pharmaceutical QC, food safety labs, and EPA-certified testing facilities.
Applications
- Residue analysis: pesticide screening in soil/water (EPA Methods 508, 525), veterinary drug residues in milk (AOAC 2012.01), and mycotoxin cleanup prior to HPLC.
- Pharmaceutical development: API purification intermediates, dissolution sample prep, and residual solvent removal per ICH Q3C guidelines.
- Clinical toxicology: urine drug screening extracts, forensic blood alcohol derivatization, and steroid metabolite isolation.
- Environmental monitoring: PAHs and PCBs concentration from large-volume water extractions (SW-846 Method 3510C), and dioxin/furan cleanup prior to HRGC-HRMS.
- Food & beverage: flavor compound isolation, fatty acid methyl ester (FAME) concentration for GC-FID, and heavy metal digestate volume reduction.
FAQ
Can the N-EVAP be used with gases other than nitrogen?
Yes—compressed air, argon, or helium may be substituted depending on analyte sensitivity; however, nitrogen remains preferred for its inertness, cost-efficiency, and compatibility with most organic solvents.
Is the water bath removable for cleaning or maintenance?
All water bath inserts are fully detachable and designed for rapid draining and wipe-down; stainless steel construction resists scaling and facilitates ISO-standard cleaning validation.
What safety features prevent overheating or gas overpressure?
Each unit includes dual redundant safeguards: a mechanical high-limit thermostat (cut-off at 100 °C) and a pressure-relief valve integrated into the gas manifold (set at 35 psig). Dry-block versions also include GFCI-certified power cords.
How is calibration verified during routine use?
Temperature uniformity is verified using NIST-traceable PT100 probes placed at multiple radial and axial locations; gas flow is validated annually with a primary-standard bubble meter or mass flow calibrator per ISO/IEC 17025 requirements.
Are replacement parts such as needles and O-rings available separately?
Yes—Organomation supplies OEM-certified consumables including stainless steel needles (P/N 100-001), PTFE-coated variants (P/N 100-002), silicone O-rings (P/N 200-005), and calibrated flow meters (P/N 300-012), all stocked for global distribution.
