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PEAK Genius AE 68 Nitrogen Generator for LC-MS and Mass Spectrometry Applications

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Brand PEAK
Origin Shanghai, China
Manufacturer Type Direct Manufacturer
Product Category Domestic
Model Genius AE 68
Instrument Type Nitrogen Generator
Nitrogen Generation Principle Hollow Fiber Membrane Separation (MEM)
Output Flow Rate 68 L/min
Output Pressure 116 psi
Nitrogen Purity 99.5%
Integrated Air Compressor Yes
Control Interface External HMI Touchscreen
Warranty 12-month on-site comprehensive warranty
Compliance Designed to meet ISO 8573-1 Class 2:2:2 compressed air quality requirements for instrument-grade nitrogen supply

Overview

The PEAK Genius AE 68 is an integrated, on-demand nitrogen generator engineered specifically to support high-sensitivity analytical instrumentation requiring stable, continuous, and contaminant-controlled nitrogen supply — particularly liquid chromatography–mass spectrometry (LC-MS), electrospray ionization (ESI), atmospheric pressure chemical ionization (APCI), and other mass spectrometric techniques demanding consistent gas performance. It employs proven hollow fiber membrane (MEM) separation technology to extract high-purity nitrogen from ambient compressed air, eliminating dependency on high-pressure nitrogen cylinders or centralized plant air systems. The system integrates a precision-engineered oil-free scroll air compressor, multi-stage filtration (coalescing, activated carbon, and ultra-fine particulate), and a proprietary membrane module optimized for long-term stability under variable load conditions. With a rated output of 68 L/min at 116 psi and verified nitrogen purity of 99.5% (v/v), the Genius AE 68 delivers laboratory-grade nitrogen meeting the operational thresholds required by modern triple quadrupole (QQQ), time-of-flight (TOF), and Orbitrap-based platforms — without introducing hydrocarbon residues, moisture, or particulates that compromise ion source cleanliness or baseline stability.

Key Features

  • Integrated oil-free scroll air compressor ensures silent, vibration-minimized operation and eliminates need for external compressed air infrastructure
  • Hollow fiber membrane separation core with proprietary surface treatment for enhanced O2/N2 selectivity and resistance to humidity-induced flux decline
  • Real-time pressure and flow monitoring via external HMI touchscreen interface with intuitive menu navigation and event logging
  • Compact footprint (W × D × H: 420 × 530 × 720 mm) designed for benchtop or under-bench installation in space-constrained MS labs
  • Automated self-diagnostics including filter saturation alerts, membrane performance trending, and compressor thermal status reporting
  • Factory-calibrated flow and pressure sensors traceable to NIST standards; optional calibration certificate available upon request

Sample Compatibility & Compliance

The Genius AE 68 is validated for continuous operation with all major LC-MS platforms, including but not limited to Thermo Fisher Scientific (Orbitrap Exploris, TSQ Altis), Waters (Xevo TQ-S, Vion IMS QTof), Agilent (6470/6495 QQQ, 6550 iFunnel Q-TOF), and Shimadzu (LCMS-8060). Its output meets the nitrogen specification requirements defined in ASTM D6352–22 (Standard Guide for Gas Supply to Mass Spectrometers) and aligns with ISO 8573-1:2010 Class 2:2:2 for particle, water, and oil content in instrument air. While not certified to FDA 21 CFR Part 11 out-of-the-box, the system supports audit-ready data export (CSV/Excel) and can be configured within a validated environment under GLP/GMP frameworks when paired with documented IQ/OQ protocols and electronic logbook integration.

Software & Data Management

The external HMI touchscreen provides local control and real-time visualization of critical parameters: inlet air pressure, post-filter dew point, membrane outlet pressure, instantaneous flow rate, and cumulative operating hours. All operational events — including filter replacement reminders, pressure drop anomalies, and startup/shutdown sequences — are timestamped and stored in non-volatile memory for up to 12 months. Data export is supported via USB port (no network connectivity required), enabling integration into laboratory information management systems (LIMS) or preventive maintenance scheduling tools. Firmware updates are performed offline using encrypted firmware packages to ensure system integrity and regulatory compliance during software lifecycle management.

Applications

  • LC-MS mobile phase nebulization and desolvation gas in ESI/APCI sources
  • Collision gas (CID) in tandem mass spectrometry workflows
  • Sheath gas for high-resolution imaging MS and MALDI-TOF instruments
  • Blank purge and carrier gas for GC-MS auxiliary systems
  • Instrument cabinet inerting and sample storage purging in regulated QC laboratories
  • Continuous nitrogen supply for automated sample preparation workstations requiring dry, particle-free gas

FAQ

Does the Genius AE 68 require external compressed air?
No — it features a fully integrated, oil-free scroll air compressor and requires only a standard 230 V / 50 Hz power connection.
What maintenance intervals are recommended?
Pre-filters require replacement every 2,000 operating hours; coalescing and activated carbon filters every 4,000 hours; membrane module service life exceeds 15,000 hours under typical lab conditions.
Can nitrogen purity be verified in-house?
Yes — optional integrated electrochemical oxygen sensor (0–1,000 ppm O2) is available for real-time purity verification and trending; calibration is traceable to NIST SRM 2621a.
Is the system compatible with ISO 17025-accredited laboratories?
Yes — when deployed with documented validation protocols (IQ/OQ/PQ), calibrated sensors, and maintained logbooks, it fulfills metrological traceability and equipment qualification requirements per ISO/IEC 17025:2017 Clause 6.4.6.
What safety certifications does it hold?
CE marked per EU Machinery Directive 2006/42/EC and EMC Directive 2014/30/EU; conforms to IEC 61010-1:2010 for laboratory electrical safety.

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