PreFluid SD300-PF25 High-Precision Dispensing Peristaltic Pump

Overview

The PreFluid SD300-PF25 is a high-precision dispensing peristaltic pump engineered for repeatable, low-pulse fluid transfer in regulated laboratory and small-scale production environments. Based on the principle of positive displacement via sequential compression of elastomeric tubing by rotating rollers, the SD300-PF25 delivers stable flow profiles across its full operational speed range (0.1–300 rpm), minimizing pulsation through dual staggered roller geometry and optimized cam profile design. Its brushless DC motor ensures thermal stability, silent operation (<45 dB(A) at 1 m), and long-term reliability without carbon brush wear or lubrication requirements. The unit complies with IEC 61000-6-3 (EMC emission) and IEC 61000-6-2 (immunity) standards, and its IP65-rated metal enclosure—formed from powder-coated stainless steel—provides protection against dust ingress and low-pressure water jets, making it suitable for cleanroom-adjacent workflows and wet-lab settings.

Key Features

• Stainless steel pump head with smooth, crevice-free surfaces compliant with ISO 14644-1 Class 7 surface roughness requirements for easy cleaning and reduced microbial retention.
• Dual staggered roller architecture ensures continuous occlusion overlap, reducing flow pulsation amplitude to ≤±1.2% CV (measured at 100 rpm with PharMed® BPT tubing, 4.8 × 2.4 mm ID/OD).
• Lever-actuated vertical pump head assembly enables single-hand tubing replacement without tools—critical for rapid changeover between batches or reagent lines.
• Integrated pre-friction system applies controlled preload before full occlusion, extending tubing service life by up to 40% compared to conventional designs (tested per ASTM D412 tensile fatigue protocol).
• Backlit LCD interface displays real-time speed, direction, elapsed time, and cumulative volume; supports user-defined dispense volume presets with auto-stop functionality.
• RS485 serial interface (Modbus RTU protocol) enables integration into SCADA systems, LIMS, or programmable logic controllers for audit-trail-capable process automation.

Sample Compatibility & Compliance

The SD300-PF25 is compatible with standard peristaltic tubing materials including silicone (e.g., Norprene® LFT), thermoplastic elastomers (e.g., PharMed® BPT), and fluoropolymer-lined options (e.g., Masterflex® C-Flex®). Tubing selection must conform to USP Class VI biocompatibility and FDA 21 CFR 177.2600 extractables specifications where used in diagnostic reagent or parenteral filling applications. The pump itself does not hold regulatory certification (e.g., ISO 13485, CE medical device), but its mechanical design and control architecture support validation under GLP/GMP frameworks—including IQ/OQ protocols—and aligns with Annex 11 (EU GMP) data integrity expectations when paired with validated software layers.

Software & Data Management

While the SD300-PF25 operates as a standalone instrument, its Modbus RTU interface permits bidirectional communication with host systems capable of logging timestamps, setpoints, actual speed, and dispense volume. When integrated into a 21 CFR Part 11-compliant environment, external software can enforce electronic signatures, audit trails, and role-based access control for all parameter changes. No proprietary PC software is bundled; however, open Modbus register maps (available in technical documentation) facilitate custom scripting in Python, LabVIEW, or MATLAB for automated calibration verification and statistical process control (SPC) charting.

Applications

• Precise volumetric dispensing of aqueous solutions in diagnostic kit manufacturing (e.g., ELISA reagents, lateral flow assay buffers).
• Low-shear transfer of heat-sensitive biologics during lyophilized drug product fill-finish simulation studies.
• Automated media preparation in microbiology labs requiring consistent inoculum volumes (e.g., 0.1–5 mL aliquots into microtiter plates).
• Calibration fluid delivery in analytical instrument sample introduction modules (e.g., ICP-MS, HPLC autosamplers).
• Controlled reagent addition in benchtop bioreactors where pulse-free flow prevents foam generation or shear-induced protein denaturation.

FAQ

What tubing sizes are supported with the PF25 pump head?
The PF25 pump head accommodates four standard inner diameter configurations: 1.6 mm, 2.4 mm, 3.1 mm, and 4.8 mm—each with fixed 2.4 mm wall thickness. Flow per revolution ranges from 0.45 mL (1.6 × 2.4 mm) to 2.7 mL (4.8 × 2.4 mm), as verified per ISO 8536-4 gravimetric test methodology.
Can the SD300-PF25 be used in sterile processing environments?
The pump itself is not sterilizable, but its IP65-rated housing and stainless-steel wetted surfaces allow placement outside Grade A/B cleanrooms with tubing routed through pass-through ports. Terminal sterilization of tubing (e.g., gamma irradiation of PharMed® BPT) is recommended for aseptic applications.
Is speed calibration traceable to NIST standards?
The internal tachometer is factory-calibrated using a laser Doppler velocimeter referenced to NIST-traceable rotational standards. Calibration certificates (including uncertainty budgets) are available upon request for metrological validation.
Does the pump support programmable multi-step dispensing sequences?
No built-in sequence programming is provided; however, multi-step logic (e.g., prime → dispense → rinse → pause) can be implemented externally via Modbus commands issued from a PLC or PC-based controller.
What is the maximum backpressure rating for the PF25 head at 300 rpm?
At full speed and with 4.8 × 2.4 mm tubing, the PF25 head maintains flow stability up to 0.25 bar (3.6 psi) backpressure, as measured per ISO 5800:2019 dynamic pressure testing protocol.