Raykol Vitae 60 Automated Liquid Handling Workstation

Overview

The Raykol Vitae 60 Automated Liquid Handling Workstation is an engineered solution for precision liquid transfer in resource-constrained or space-limited laboratory environments—including mobile testing vehicles, field-deployable containment units (e.g., biosafety-equipped mobile labs), and compact core facilities. Built upon a modular air-displacement pipetting architecture, the system delivers traceable, reproducible volumetric delivery across a broad dynamic range (1–1000 µL), supporting both low-volume nucleic acid handling and higher-volume reagent preparation tasks. Its design emphasizes operational robustness, compliance-ready functionality, and seamless integration into standardized molecular workflows—particularly those governed by ISO/IEC 17025, CLIA, or CAP-accredited diagnostic protocols.

Key Features

• Modular 6-position deck layout: Accommodates tubes (0.2 mL to 50 mL), reservoirs, PCR strips, 96-well and 384-well plates (flat, skirted, or low-profile), and deep-well plates—configurable via user-defined deck maps and physical adapter inserts.
• Dual-range air-displacement pipetting: Equipped with interchangeable 4- or 8-channel pipetting modules; supports single-channel aspiration/dispensing for serial dilution or plate reformatting, as well as multi-channel bulk transfer.
• High-precision volumetric performance: Certified accuracy (CV ≤ 0.5% at 200–1000 µL) aligns with ISO 8655-2 requirements for air-displacement pipettes; full calibration traceability supported via onboard gravimetric verification routines.
• Expandable functional modules: Optional temperature-controlled deck (4–45 °C), orbital shaking (200–1200 rpm), and barcode scanning modules enable unattended workflow extension without hardware redesign.
• Open consumables ecosystem: Compatible with third-party tips (including filtered and low-retention variants), tubes, and microplates—reducing long-term operational cost and eliminating vendor lock-in.

Sample Compatibility & Compliance

The Vitae 60 supports direct interfacing with common laboratory consumables from major global suppliers (e.g., Eppendorf, Thermo Fisher Scientific, Corning, Greiner Bio-One). Its pipetting geometry accommodates ANSI/SLAS-compliant footprint dimensions and maintains Z-height tolerances required for robotic arm compatibility. All liquid handling operations adhere to Good Laboratory Practice (GLP) and Good Manufacturing Practice (GMP) documentation standards: audit trails record operator ID, timestamp, protocol version, tip usage, and error logs; electronic signatures comply with FDA 21 CFR Part 11 requirements when deployed with validated software configurations.

Software & Data Management

The workstation runs Raykol’s proprietary VitaeControl™ software—a Windows-based, drag-and-drop interface enabling rapid protocol development without scripting. Each step—whether single-aspiration-multi-dispense, column-wise transfer, or random well selection—is parameterized independently (aspiration/dispense speed, tip immersion depth, pre-wet cycles, post-aspiration blowout volume). Protocols are exportable as XML files for version control and cross-platform validation. Integrated data export supports CSV, Excel, and LIMS-compatible formats (ASTM E1384, HL7 v2.x). Software updates include cryptographic integrity checks and rollback capability for regulatory continuity.

Applications

• Pathogen detection workflows: SARS-CoV-2 RT-qPCR master mix setup, multiplex viral panel assembly, and extraction-to-amplification bridging in high-throughput screening environments.
• Nucleic acid quantification and normalization: cDNA library prep, gDNA shearing QC, and qPCR standard curve generation with inter-run coefficient-of-variation <1.2%.
• Functional genomics: CRISPR guide RNA complex assembly, siRNA transfection plate formatting, and ChIP-seq library indexing.
• Clinical assay development: ELISA plate coating, calibrator dilution series, and immunoassay validation sample preparation under ISO 15189 conditions.
• Biopharmaceutical QC: Reference standard dilution, potency assay plate setup, and stability-indicating method transfers.

FAQ

Does the Vitae 60 support GLP/GMP-compliant operation?
Yes—when configured with audit trail logging enabled, electronic signature authentication, and protocol version control, it meets core ALCOA+ data integrity principles and supports 21 CFR Part 11 compliance.
Can the system handle viscous or volatile liquids?
It supports DMSO, glycerol (up to 40% v/v), and ethanol-based solutions using optimized aspiration/dispense parameters and low-retention tips; however, non-aqueous solvents require dedicated tip conditioning protocols.
Is remote monitoring or troubleshooting available?
The workstation includes Ethernet and optional Wi-Fi connectivity; remote desktop access (via TLS-secured VNC) and real-time status dashboards are supported through Raykol’s cloud-enabled ServiceLink™ platform.
What maintenance intervals are recommended?
Daily tip ejection verification, weekly gravimetric accuracy check (per ISO 8655-6), and biannual mechanical calibration of Z-axis positioning and pipette motor torque—documented in the included Maintenance Logbook template.
How is software validation handled for regulated environments?
Raykol provides IQ/OQ documentation packages, including test scripts, acceptance criteria, and evidence of boundary condition verification; PQ support is delivered in collaboration with certified third-party validation partners.