RO Membrane Cartridge for MilliporeSigma IQ7005, RiOs 8 & Elix 5 Systems
| Brand | Deepflow |
|---|---|
| Origin | Shanghai, China |
| Manufacturer Type | Authorized Distributor |
| Regional Category | Domestic (China) |
| Model | CYRC60HA1 |
| Pricing | Available Upon Request |
Overview
The CYRC60HA1 RO membrane cartridge is a precision-engineered replacement component designed exclusively for integration into MilliporeSigma’s IQ7005, RiOs 8, and Elix 5 ultra-pure water systems. It operates on the principle of cross-flow reverse osmosis—applying hydraulic pressure greater than the osmotic pressure across a semi-permeable polyamide thin-film composite (TFC) membrane to reject >99% of dissolved ions, colloids, organic molecules (>100 Da), bacteria, and pyrogens from feed water. This stage serves as the primary purification barrier upstream of deionization and ultraviolet oxidation modules, ensuring consistent production of Type I+ ultrapure water (resistivity ≥18.2 MΩ·cm at 25 °C, TOC <5 ppb) compliant with ASTM D1193-20, ISO 3696:1987, and CLSI EP21-A guidelines for clinical and analytical laboratory applications.
Key Features
- Optimized dimensional and hydraulic compatibility with IQ7005, RiOs 8, and Elix 5 system housings—ensures leak-free installation and full flow-path alignment without modification.
- Polyamide TFC membrane with standardized 100 gpd (378 L/day) nominal flux at 225 psi (15.5 bar) and 25 °C feed water temperature.
- Integrated pre-filtered feed channel design minimizes fouling risk from particulates and chlorine residuals, extending service life under typical municipal tap water conditions.
- Manufactured in an ISO 9001-certified facility in Shanghai; each batch undergoes post-assembly integrity testing per ASTM F838-22 (bacterial retention validation).
- Non-sterile, non-pyrogenic packaging; compatible with standard system sanitization protocols including hot water (80–85 °C) and hydrogen peroxide cycles.
Sample Compatibility & Compliance
The CYRC60HA1 is validated for use with municipal, well, or pre-treated water sources meeting NSF/ANSI Standard 61 for potable water contact materials. It is not intended for direct seawater, high-silica (>2 ppm), or high-iron (>0.3 ppm) feed streams without upstream pretreatment. The cartridge complies with RoHS Directive 2011/65/EU and REACH Annex XVII restrictions on hazardous substances. When installed in IQ7005/RiOs 8/Elix 5 platforms operating under GLP or GMP environments, its replacement interval (typically 12–24 months, depending on feed quality and usage volume) must be recorded in system maintenance logs to satisfy FDA 21 CFR Part 11 audit requirements for traceability.
Software & Data Management
While the CYRC60HA1 itself contains no embedded electronics or firmware, its operational status is monitored indirectly via the host system’s integrated sensors: feed pressure, permeate conductivity, rejection rate calculation, and cumulative runtime counters. In IQ7005 systems equipped with MilliporeSigma’s Elix Connect software (v3.2+), membrane performance metrics—including real-time salt rejection % and predictive end-of-life alerts—are logged with time-stamped, user-auditable entries. All data exports conform to CSV and PDF formats suitable for inclusion in laboratory quality records per ISO/IEC 17025:2017 clause 7.5.2.
Applications
- HPLC and UHPLC mobile phase preparation requiring low-conductivity, low-TOC water to prevent column contamination and baseline drift.
- Cell culture media formulation where endotoxin levels must remain below 0.03 EU/mL per USP .
- Atomic absorption spectroscopy (AAS) and inductively coupled plasma mass spectrometry (ICP-MS) blank minimization for trace metal analysis.
- PCR reagent preparation and next-generation sequencing library construction demanding DNase/RNase-free water.
- Calibration of conductivity and TOC analyzers used in pharmaceutical water system qualification (IQ/OQ/PQ).
FAQ
Is the CYRC60HA1 certified by MilliporeSigma as an OEM-equivalent part?
No—it is a third-party engineered replacement distributed by Deepflow under authorized channel partnership; it meets functional and dimensional specifications but carries no MilliporeSigma branding or warranty.
Can this cartridge be used in systems other than IQ7005, RiOs 8, or Elix 5?
It is dimensionally and port-configured only for those three models; use in non-compatible systems may result in seal failure, bypass leakage, or pressure drop anomalies.
What is the recommended storage condition prior to installation?
Store unopened in original vacuum-sealed packaging at 5–30 °C, away from direct UV exposure and oxidizing agents; do not freeze.
Does the cartridge include a housing or O-rings?
No—CYRC60HA1 is the membrane element only; reuse of original system housing and factory-installed seals is required.
How is membrane performance verified after installation?
Monitor initial permeate conductivity (should be ≤5 µS/cm within 2 hours of startup) and track rejection efficiency weekly using the formula: [(Feed Conductivity − Permeate Conductivity) / Feed Conductivity] × 100%.
