Shanghai Yarong RE-52CS-2 Rotary Evaporator

Overview

The Shanghai Yarong RE-52CS-2 Rotary Evaporator is an entry-level yet robust benchtop system engineered for solvent removal, concentration, and gentle sample recovery under reduced pressure. It operates on the principle of vacuum-assisted rotary distillation: a rotating evaporation flask increases surface area and promotes uniform thin-film formation, while controlled heating (via external thermostatic bath) and precise vacuum regulation enable efficient, low-temperature evaporation of heat-sensitive compounds. The horizontal double-surface condenser ensures high-efficiency vapor condensation across a broad range of solvents—including water, ethanol, acetone, ethyl acetate, and chloroform—without requiring cryogenic cooling. Its design prioritizes operational stability, thermal consistency, and mechanical reproducibility, making it suitable for routine purification workflows in academic teaching labs, QC environments, and pilot-scale R&D settings.

Key Features

• Electronically adjustable rotation speed (0–120 rpm) with digital feedback control, enabling optimized film thickness and evaporation kinetics for diverse viscosities and boiling points.
• Precision temperature regulation from ambient to 99 °C, with ±1 °C accuracy maintained via PID-controlled external heating bath (e.g., Yarong B-260), minimizing thermal degradation of labile biomolecules or active pharmaceutical ingredients.
• Horizontal double-surface condenser constructed from borosilicate glass (3.3), offering extended condensation path length and superior heat exchange efficiency compared to vertical coil designs—especially critical for high-boiling-point solvents or elevated vacuum conditions.
• Standardized conical ground-glass joints (29/32 for rotating flask; 24/29 for collection flask) ensure leak-tight vacuum integrity and interchangeability with common laboratory glassware.
• Stainless steel mainframe with corrosion-resistant coating and integrated vacuum seal housing, supporting long-term reliability in humid or solvent-rich lab environments.
• Modular architecture allows seamless integration with auxiliary equipment: vacuum controllers (e.g., diaphragm pumps with oil-free operation), chiller units, and inert gas manifolds for oxygen-sensitive applications.

Sample Compatibility & Compliance

The RE-52CS-2 accommodates samples ranging from aqueous buffers and organic extracts to polymer solutions and crude reaction mixtures. Its 1 L rotating flask supports batch volumes up to 600 mL, while the 500 mL collection flask provides sufficient headspace for foaming-prone solutions. All wetted parts are fabricated from borosilicate glass (DIN ISO 3585) and PTFE-sealed joints, ensuring chemical compatibility with most common solvents per ASTM D471 and USP . While not certified for GMP manufacturing use, the system meets general laboratory safety standards (IEC 61010-1) and supports GLP-aligned documentation when paired with calibrated external baths and vacuum gauges. Routine maintenance—such as joint greasing, gasket inspection, and condenser cleaning—is fully accessible without tools.

Software & Data Management

As a manually operated analog system, the RE-52CS-2 does not include embedded software or digital data logging. However, its operational parameters (rotation speed, bath temperature, and vacuum level) are compatible with third-party monitoring systems: analog outputs from external bath controllers (e.g., B-260’s 0–10 V signal port) and vacuum transducers can be interfaced with LabVIEW, MATLAB, or SCADA platforms for trend analysis and audit trail generation. For regulated environments requiring 21 CFR Part 11 compliance, users may implement procedural controls—including logbook entries, instrument calibration records, and SOP-defined setpoint validation—to support traceability during method development or stability studies.

Applications

• Concentration of natural product extracts in phytochemistry and nutraceutical research.
• Solvent exchange and intermediate drying in synthetic organic chemistry workflows.
• Removal of low-boiling solvents prior to lyophilization or crystallization steps in API process development.
• Routine solvent recovery and reuse in fine chemical manufacturing pilot lines.
• Teaching fundamental principles of vacuum distillation, Raoult’s law, and phase equilibria in undergraduate physical chemistry laboratories.

FAQ

Is the RE-52CS-2 compatible with vacuum controllers for automated pressure ramping?
Yes—its vacuum inlet accepts standard 1/4″ hose barbs and integrates with programmable vacuum controllers (e.g., Vacuubrand VRV or KNF NP series) for stepwise pressure reduction during sensitive evaporations.
Can the condenser be upgraded to a chilled recirculating system?
The horizontal condenser accepts standard 10/12 mm coolant tubing; users may connect it to external chillers (e.g., Huber CC-K or Polyscience 4510) for sub-ambient condensation when processing high-vapor-pressure solvents.
What is the maximum recommended vacuum level for stable operation?
Optimal performance is achieved at 50–200 mbar (absolute); deeper vacuums (<20 mbar) require careful optimization of rotation speed and bath temperature to prevent bumping or motor overload.
Does Shanghai Yarong provide calibration certificates for the B-260 bath used with this system?
Calibration documentation is available upon request and follows ISO/IEC 17025-accredited procedures when performed by authorized service partners.
Are replacement flasks and seals available as spare parts?
Yes—Yarong supplies OEM-certified rotating flasks, collection flasks, PTFE stopcocks, and silicone vacuum tubing under part numbers traceable to the RE-52CS-2 service manual.