ShiPing SLSK-2018R Plus Dual-Zone Dual-Controlled Incubator Shaker

Overview

The ShiPing SLSK-2018R Plus Dual-Zone Dual-Controlled Incubator Shaker is an engineered platform for simultaneous, independent control of temperature and orbital agitation across two parallel working chambers. Designed for rigorous life science applications—including microbial cultivation, protein expression, enzymatic assays, hybridization protocols, and cell-based bioprocessing—the instrument integrates precision thermal regulation with low-vibration mechanical oscillation based on a single-axis parallelogram dynamic balance drive mechanism. Its dual-zone architecture enables comparative experiments under divergent thermal conditions (e.g., 25°C vs. 37°C) while maintaining identical shaking parameters—critical for kinetic studies, strain screening, or process optimization in pharmaceutical development and academic research. The system operates on the principle of forced convection air circulation combined with high-efficiency variable-frequency refrigeration, ensuring stable setpoint maintenance even at sub-ambient temperatures (down to 4°C), without evaporator frost accumulation.

Key Features

• Dual independent incubation zones with fully separate PID temperature and speed control loops—each with dedicated 7-inch true-color touchscreen interface supporting multi-user authentication and role-based access levels.
• Parallelogram-driven single-axis orbital motion system fabricated from high-strength ductile iron (ASTM A536 Grade 65-45-12), minimizing mechanical friction, wear, and acoustic emission (10,000 h MTBF).
• High-reliability refrigeration subsystem utilizing R134a eco-friendly refrigerant and inverter-driven compressors—delivering up to 30% energy reduction versus fixed-speed systems and eliminating defrost cycles under continuous operation.
• GMP-compliant interior construction: 304 stainless steel mirror-finish chamber walls with radius-rounded corners; electropolished 304 stainless steel spring plates and flask clamps (hardness: 420 HV, elasticity retention >360°); seamless welds and non-porous surfaces validated for cleanroom-compatible cleaning protocols.
• Integrated safety architecture including dual independent overtemperature cutoffs (electronic + mechanical), overspeed detection, motor current monitoring, refrigeration overload protection, and door-open auto-stop functionality.
• Comprehensive data integrity framework compliant with FDA 21 CFR Part 11 requirements: electronic audit trail, user-level permission tiers (admin/operator/visitor), parameter change logging, real-time curve visualization, and timestamped alarm history exportable via USB or Ethernet.

Sample Compatibility & Compliance

The SLSK-2018R Plus accommodates standard laboratory vessels—including Erlenmeyer flasks (25–2000 mL), test tubes, microtiter plates (via optional plate holders), and custom bioreactor bags—on two interchangeable 498 × 490 mm stainless steel platforms. Each zone supports configurable mounting options: universal bottle clamps, spring-loaded trays, enzyme-linked immunosorbent assay (ELISA) plate adapters, and adhesive mats. All wetted materials meet ISO 8573-1 purity class 4 for compressed air compatibility and comply with USP for plastic component extractables. The unit is CE-marked per EN 61000-6-2 (EMC immunity) and EN 61000-6-4 (EMC emissions), and conforms to IEC 61010-1:2010 for laboratory equipment safety. Optional IQ/OQ documentation packages support GxP validation per ASTM E2500 and Annex 11 guidelines.

Software & Data Management

Embedded firmware supports both fixed-setpoint and programmable ramp-soak profiles (up to 5 programs × 30 segments). Real-time data—including actual vs. target temperature, RPM, elapsed time, and alarm status—is displayed synchronously on the main screen and logged internally with millisecond timestamp resolution. Data export formats include CSV and PDF reports compatible with LIMS integration. Remote supervision is enabled via TCP/IP Ethernet or optional Wi-Fi module, permitting secure web-based monitoring and parameter adjustment through TLS 1.2–encrypted connections. Audit trails record all user actions—including login/logout events, parameter modifications, and manual overrides—with immutable digital signatures. Firmware updates are performed via signed .bin files verified by SHA-256 checksum prior to installation.

Applications

This incubator shaker serves as a core platform in QC microbiology labs performing sterility testing per USP , in upstream bioprocess development for recombinant protein expression in E. coli or yeast, and in environmental monitoring laboratories conducting BOD/COD assays per ISO 5815-1. It supports ISO/IEC 17025-accredited methods for bacterial growth kinetics, antimicrobial susceptibility testing (AST), and vaccine stability assessment under accelerated aging conditions. In molecular biology workflows, it enables consistent hybridization kinetics for Northern/Southern blotting and facilitates uniform mixing during chromatin immunoprecipitation (ChIP) sample preparation. Its dual-zone capability is especially valuable for DOE-based experimental designs comparing thermal effects on metabolic activity or gene expression across isogenic strains.

FAQ

Does the SLSK-2018R Plus support GLP-compliant data archiving?
Yes—full electronic audit trail, user authentication, and tamper-evident data export meet GLP requirements for raw data retention and traceability.

Can both zones operate at different temperatures and speeds simultaneously?
Yes—each zone has independent PID controllers for temperature (4–60°C) and rotational speed (30–300 rpm), with orbit amplitude fixed at Φ25 mm.

Is remote monitoring available without third-party software?
Yes—the built-in web server allows browser-based access via static IP or DHCP-assigned address; no proprietary client installation required.

What validation support is provided for regulated environments?
Factory-issued IQ/OQ protocols, calibration certificates traceable to NIST standards, and risk-based URS mapping documentation are available upon request.

Are UV sterilization cycles programmable and logged?
UV lamp activation is manually initiated but automatically logged with duration, timestamp, and operator ID in the audit trail.