SurgiVet V6004 Small Animal Multiparameter Patient Monitor
| Brand | Harvard Apparatus |
|---|---|
| Origin | USA |
| Manufacturer Type | Authorized Distributor |
| Import Status | Imported |
| Model | V6004 |
| Pricing | Available Upon Request |
Overview
The SurgiVet V6004 Small Animal Multiparameter Patient Monitor is a clinical-grade, non-invasive physiological monitoring system engineered for real-time, high-fidelity assessment of hemodynamic and respiratory parameters in laboratory rodents, rabbits, ferrets, and other small mammals weighing 20 g to 5 kg. Designed around oscillometric and photoplethysmographic principles, the V6004 delivers continuous, artifact-resistant measurements of systolic, diastolic, and mean arterial pressure (SAP, DAP, MAP), central venous pressure (CVP), peripheral capillary oxygen saturation (SpO₂), and pulse rate. Its architecture integrates calibrated pressure transducer inputs, dual-wavelength red/infrared LED photodetectors, and adaptive signal filtering algorithms optimized for low-perfusion, high-heart-rate physiological conditions typical of murine and lagomorph models. The device complies with IEC 60601-1 (3rd ed.) safety standards for medical electrical equipment and meets essential performance criteria outlined in ISO 80601-2-56 for patient monitors used in research settings.
Key Features
- Non-invasive oscillometric blood pressure measurement with automated cuff inflation/deflation cycles and dynamic pressure range adaptation (0–300 mmHg)
- Dual-wavelength (660 nm / 940 nm) SpO₂ sensing with motion-tolerant algorithm and perfusion index (PI) output
- Real-time pulse waveform display with beat-to-beat interval analysis and arrhythmia flagging
- Configurable CVP monitoring via external pressure transducer input (0–100 mmHg range, ±1 mmHg accuracy)
- Modular design supporting optional add-ons including temperature probe interface (thermistor-based, -20°C to +50°C) and ECG lead set (bipolar limb leads)
- Backlit graphical LCD with adjustable contrast, capable of simultaneous 4-parameter numeric display and trend waveform overlay
- Internal rechargeable battery providing ≥4 hours of continuous operation; AC adapter included
Sample Compatibility & Compliance
The V6004 is validated for use across common preclinical species including C57BL/6 and BALB/c mice, Sprague-Dawley and Wistar rats, New Zealand White rabbits, and guinea pigs. Cuff sizes (XS, S, M) are selected based on limb or tail circumference per AALAC-recommended guidelines. All pressure sensors are traceably calibrated against NIST-traceable deadweight testers annually. The system supports GLP-compliant data acquisition when paired with optional timestamped analog output (0–5 V DC) and adheres to FDA 21 CFR Part 11 requirements for electronic records when used with validated third-party data logging software. It is not intended for human use and carries appropriate labeling per 21 CFR §801.109.
Software & Data Management
While the V6004 operates as a standalone monitor, its analog outputs (pressure, SpO₂, pulse) enable integration into existing data acquisition platforms such as LabChart (ADInstruments), PowerLab systems, or custom MATLAB/Python-based acquisition scripts. Optional RS-232 serial interface allows ASCII-formatted parameter streaming at 1 Hz resolution for long-term protocol logging. All displayed values include built-in statistical reporting (min/max/mean over user-defined intervals) and automatic alarm thresholds (configurable high/low limits with visual and audible alerts). Audit trails for parameter changes and alarm events are retained in volatile memory for up to 72 hours.
Applications
- Cardiovascular pharmacology studies assessing acute hemodynamic responses to vasoactive agents
- Anesthesia monitoring during surgical procedures under isoflurane, ketamine/xylazine, or pentobarbital regimens
- Respiratory challenge models (e.g., hypoxia, LPS-induced inflammation) requiring concurrent SpO₂ and BP tracking
- Toxicology endpoints involving circulatory stability assessment post-dose administration
- Longitudinal recovery monitoring following implantation of telemetry devices or vascular catheters
- Training platform for veterinary and biomedical graduate students in rodent physiology techniques
FAQ
Is the V6004 compatible with telemetry systems?
Yes — its analog outputs can be synchronized with implanted telemetry receivers (e.g., Data Sciences International DSI TA-F10 or HD-S10) for hybrid wired/wireless monitoring configurations.
Does it support pediatric or neonatal rodent monitoring?
The XS cuff and high-sensitivity SpO₂ algorithm are validated down to 20 g body weight; however, MAP accuracy below 15 g is not clinically established.
Can pressure calibration be performed in-house?
No — recalibration requires factory service using NIST-traceable reference standards; field verification is supported via zero-balance and pressure step-check routines.
What is the warranty coverage?
Harvard Apparatus provides a 2-year limited warranty covering parts and labor for defects in materials and workmanship under normal laboratory use.
Is FDA clearance required for use in academic research?
No — the V6004 is classified as a research-use-only (RUO) device outside the scope of FDA 510(k) clearance when deployed exclusively in non-clinical animal studies.
