TDL-5M Desktop High-Capacity Refrigerated Centrifuge
| Key | Origin: Shanghai, China |
|---|---|
| Manufacturer Type | Authorized Distributor |
| Max Speed | 5000 rpm |
| Max RCF | 4390 × g |
| Temperature Range | −20 °C to +40 °C |
| Timer | 0–99 min |
| Dimensions (L×W×H) | 460 × 550 × 400 mm |
| Weight | 75 kg |
| Power Supply | AC 220 V, 50 Hz, 15 A |
| Certifications | ISO 9001:2000, Hunan Medical Device Production Filing No. 20030027, Registration Nos. Xiang Chang Yao Guan Xie (Zhun) Zi 2003 No. 1410036–1410039 |
Overview
The TDL-5M Desktop High-Capacity Refrigerated Centrifuge is an engineered solution for routine and high-throughput separation tasks in clinical laboratories, pharmaceutical quality control, and academic research settings. Designed around a brushless DC motor drive system and microprocessor-based control architecture, it delivers precise rotational speed regulation, consistent thermal management, and reproducible centrifugal force application across variable sample loads. Its refrigeration system maintains chamber temperature between −20 °C and +40 °C, enabling temperature-sensitive separations—including plasma fractionation, cell pellet recovery, and enzyme stability assays—without thermal degradation. Unlike ultra-high-speed instruments, the TDL-5M operates within the low-speed centrifugation range (up to 5000 rpm), making it optimal for applications requiring gentle sedimentation of large-volume or delicate biological suspensions, such as whole blood processing, tissue homogenate clarification, and microbial culture harvesting.
Key Features
- Microprocessor-controlled operation with digital LED display for real-time monitoring of speed (rpm), RCF (×g), time remaining, and chamber temperature.
- Brushless DC motor ensures maintenance-free operation, reduced electromagnetic interference, and extended service life under continuous duty cycles.
- Electronic safety door lock with interlock mechanism prevents accidental lid opening during rotation; automatic rotor deceleration upon lid detection.
- Nine-step programmable acceleration/deceleration profiles (0–9) allow optimization of pelleting integrity for fragile samples—e.g., avoiding resuspension of mononuclear cells or disruption of protein complexes.
- Automatic RCF calculation and setting function: input rotor radius and desired g-force; system computes and applies corresponding rpm—critical for method transfer compliance per ISO/IEC 17025 and CLIA requirements.
- Comprehensive safety suite includes overspeed protection, overtemperature cutoff, imbalance detection, and motor overload monitoring—all logged with timestamped event records for GLP/GMP traceability.
Sample Compatibility & Compliance
The TDL-5M supports dual horizontal rotor configurations optimized for volumetric flexibility and regulatory alignment. Rotor 1 accommodates four 100 mL tubes at 5000 rpm (4390 × g), suitable for large-scale serum/plasma preparation compliant with CLSI GP44-A4 guidelines. Rotor 2 offers multi-format compatibility: eight 50 mL conical tubes, twenty-four 15 mL centrifuge tubes, or seventy-two 7 mL sample vials—all operating at 4000 rpm (2810 × g). All rotors are balanced per ISO 15195:2018 for analytical centrifuge calibration standards. The instrument meets ISO 9001:2000 quality management system requirements and carries medical device registration certificates issued by the Hunan Provincial Medical Devices Administration (Registration Nos. 2003-1410036 through 1410039), confirming conformity with China’s Class II medical device regulations for in vitro diagnostic sample preparation equipment.
Software & Data Management
While the TDL-5M operates via embedded firmware without external PC connectivity, its internal memory stores up to 10 user-defined protocols with full parameter logging—including setpoints, actual run values, error codes, and runtime duration. Event logs support audit-ready documentation for FDA 21 CFR Part 11–aligned environments when paired with laboratory information management systems (LIMS) via manual export. Timestamped safety alerts (e.g., “Overtemp Alert – 2024-05-12 14:22:08”) satisfy basic GLP record-keeping requirements for QC laboratories performing routine hematology or biobanking workflows.
Applications
- Clinical diagnostics: Separation of serum, plasma, and buffy coat from whole blood specimens (per CAP-accredited protocols).
- Pharmaceutical manufacturing: Clarification of fermentation broths, purification intermediate handling, and stability study sample preparation per ICH Q5C.
- Academic research: Isolation of mitochondria, nuclei, and extracellular vesicles from cultured mammalian cells using differential centrifugation steps.
- Food & beverage testing: Fat separation in milk homogenates, sediment analysis in juice concentrates, and pathogen concentration from liquid food matrices.
- Veterinary labs: Processing of equine synovial fluid, bovine colostrum, and avian blood samples requiring controlled thermal conditions.
FAQ
What is the maximum relative centrifugal force (RCF) achievable with the TDL-5M?
The instrument achieves a maximum RCF of 4390 × g using Rotor 1 (100 mL × 4) at 5000 rpm.
Does the TDL-5M comply with international quality standards for regulated laboratories?
Yes—it holds ISO 9001:2000 certification and is registered as a Class II medical device in China, supporting validation activities under ISO/IEC 17025 and GxP frameworks.
Can the centrifuge maintain sub-zero temperatures during extended runs?
Yes—the compressor-based cooling system sustains −20 °C throughout the full 99-minute timer range, verified per IEC 61010-2-020 thermal stability testing.
Is rotor imbalance detection automated?
Yes—vibration sensors continuously monitor load symmetry; the system halts operation and displays an error code if imbalance exceeds 5 mm displacement threshold.
Are replacement rotors and adapters available through authorized channels?
Yes—original-equipment manufacturer (OEM) rotors, tube adapters, and calibration certificates are supplied exclusively through certified distributors to ensure mechanical integrity and regulatory continuity.
