Thermo Fisher Trace DSQ Single Quadrupole Gas Chromatography-Mass Spectrometer (Used Unit)

Overview

The Thermo Fisher Trace DSQ is a benchtop single quadrupole gas chromatography–mass spectrometry (GC–MS) system engineered for robust routine analysis in regulated and research laboratories. Based on electron ionization (EI) and chemical ionization (CI) source technologies, the Trace DSQ employs a high-transmission molybdenum quadrupole mass filter with a curved pre-quadrupole to suppress neutral particle background and enhance signal-to-noise ratio. Its vacuum architecture integrates selectable turbo-molecular pump configurations (70 L/s, 250 L/s, or dual 200 L/s), ensuring stable high-vacuum conditions essential for consistent ion transmission and long-term detector stability. Designed as a fully integrated platform, the Trace DSQ couples with the Thermo Trace GC—capable of seven-ramp, eight-setpoint temperature programming and heating rates from 0.1 to 120 °C/min—to deliver precise retention time reproducibility and method transferability across diverse sample matrices.

Key Features

• Single quadrupole mass analyzer with molybdenum rods and integrated curved pre-quadrupole for improved mass filtering efficiency and reduced chemical noise
• Dual-mode ion source supporting both EI and CI operation; CI reaction gas flow controlled electronically for rapid polarity switching without venting
• Hot-swap CI ion source cartridge enables source exchange during active acquisition—minimizing instrument downtime
• Optional direct insertion probe (DIP) for thermally labile or non-volatile compounds, with programmable three-step temperature ramping up to 450 °C
• Mass range of 1–1050 amu and mass stability of ≤0.1 amu over 12 hours—validated per ASTM E1510 and ISO/IEC 17025 traceable protocols
• Refurbishment includes full vacuum integrity testing, electron multiplier gain calibration, quadrupole tuning verification, and GC inlet/column oven performance validation

Sample Compatibility & Compliance

The Trace DSQ supports broad-spectrum volatile and semi-volatile organic compound (VOC/SVOC) analysis—including pesticides, PAHs, PCBs, residual solvents, flavor/aroma volatiles, and environmental contaminants—in compliance with EPA Methods 502.2, 524.2, 8270, and 8321B. Its EI/CI flexibility allows structural confirmation via molecular ion detection (CI) and fragmentation pattern generation (EI), meeting USP , ICH Q2(R2), and GLP audit requirements. All refurbished units undergo documentation per ISO 9001:2015 quality procedures, including as-found/as-left test reports, preventive maintenance logs, and 6-month hardware warranty coverage. No software license transfer is included; users must procure current Thermo Xcalibur™ licensing separately.

Software & Data Management

Data acquisition and processing are performed using Thermo Xcalibur™ software (versions compatible with Windows 7/10, 64-bit). The system supports audit-trail-enabled workflows compliant with FDA 21 CFR Part 11 when deployed with appropriate IT infrastructure and electronic signature configuration. Raw data files (.RAW) are fully compatible with third-party spectral libraries (NIST, Wiley) and open-format conversion tools (e.g., MSConvert). Batch processing, automated calibration curve generation, peak integration with customizable baselines, and report templates meet routine QC/QA reporting needs. Instrument control modules include real-time GC oven and MS source parameter monitoring, with configurable alarm thresholds for vacuum level, filament emission current, and detector voltage.

Applications

The Trace DSQ serves as a validated platform for environmental testing laboratories performing soil, water, and air extract analysis; pharmaceutical QC labs conducting residual solvent testing per ICH Q3C; food safety labs screening for mycotoxins and pesticide residues; and forensic toxicology units analyzing drugs of abuse in biological matrices. Its sensitivity (1 pg octafluoronaphthalene, S/N ≥ 50:1 in full-scan mode) and mass accuracy support identification-level confidence under ISO/IEC 17025 accreditation. The system is routinely employed in method development for complex matrix extractions requiring selective ion monitoring (SIM) or targeted scan modes—particularly where cost-effective, reliable single-quadrupole performance is prioritized over high-resolution mass spectrometry capabilities.

FAQ

Is this unit eligible for extended service contracts beyond the 6-month warranty?
Yes—qualified buyers may purchase Thermo Fisher-certified extended maintenance agreements covering parts, labor, and remote diagnostics support.
Does the refurbishment include replacement of consumables such as filaments, gaskets, and column ferrules?
All critical consumables are replaced during refurbishment, including dual filaments, source gaskets, ion gauge sensors, and transfer line O-rings.
Can the Trace DSQ be upgraded to support modern data systems like Chromeleon or Empower?
No—the Trace DSQ communicates exclusively via Thermo Xcalibur™; it does not support Waters Empower or Thermo Chromeleon drivers.
What documentation accompanies the instrument upon delivery?
Each unit ships with a Certificate of Refurbishment, full calibration report, vacuum leak test record, GC–MS system performance verification data, and OEM user manuals in English.
Is installation and on-site qualification included in the quoted price?
Installation, site preparation guidance, and basic operational qualification (OQ) support are provided remotely; on-site IQ/OQ services are available at additional cost.