Thermo Scientific CO₂-Resistant Orbital Shaker
| Brand | Thermo Fisher Scientific |
|---|---|
| Origin | Shanghai, China |
| Manufacturer Type | Original Equipment Manufacturer (OEM) |
| Product Category | Domestic |
| Model | Resistant Shaker |
| Instrument Type | Air-Jacketed Constant-Temperature Orbital Shaker |
| Timer Range | 0–99 h 59 min or Continuous Operation |
| Oscillation Speed | 30–300 rpm |
| Orbit Diameter | 19 mm |
| Temperature Range | 4–60 °C |
| Number of Platforms | 1 |
Overview
The Thermo Scientific CO₂-Resistant Orbital Shaker is an engineered solution for controlled agitation of biological samples under high-CO₂ and high-humidity environments—specifically designed for integration within standard CO₂ incubators. Unlike conventional shakers, its mechanical architecture incorporates corrosion-resistant alloys, sealed magnetic drive systems, and non-outgassing polymer components to maintain operational integrity at up to 20% CO₂ concentration and relative humidity levels exceeding 95%. The device operates on a brushless DC motor with direct magnetic coupling—eliminating belt wear, lubrication requirements, and particulate generation—making it compliant with cleanroom-adjacent biosafety standards. Its compact footprint (W × D × H ≤ 320 × 320 × 180 mm) enables unobstructed placement on incubator shelves without impeding gas circulation or temperature uniformity. Thermal management is optimized via low-power dissipation design (<8 W at 200 rpm, 37°C), ensuring minimal heat load on the incubator chamber and preserving setpoint stability across ISO 14644 Class 7–8 ambient conditions.
Key Features
- Magnetic drive system eliminates mechanical belts and shaft seals—reducing maintenance intervals and eliminating contamination risk from lubricants or particulates
- Stainless steel 316L housing and anodized aluminum platform resist pitting and crevice corrosion in prolonged CO₂/H₂O exposure
- Externally mounted controller with backlit LED interface allows parameter adjustment without opening the incubator door—preserving internal CO₂ concentration and humidity
- Precise PID-controlled heating with dual-sensor feedback (ambient + platform) ensures ±0.3°C temperature accuracy across the 4–60°C range
- Orbital motion with 19 mm fixed-diameter orbit delivers consistent shear profiles suitable for suspension cultures, microbial growth, and hybridization assays
- Programmable timer supports both timed runs (0–99 h 59 min) and continuous operation modes with automatic restart after power interruption
Sample Compatibility & Compliance
The shaker accommodates standard labware including flasks (50–2000 mL), deep-well plates, multi-well culture dishes, and custom bioreactor vessels via interchangeable clamping accessories (e.g., universal flask holders, microplate adapters, and silicone-gasketed platforms). All wetted surfaces comply with USP Class VI biocompatibility testing, and material certifications include RoHS Directive 2011/65/EU and REACH Annex XIV SVHC screening. The system meets IEC 61010-1:2010 safety requirements for laboratory equipment and is compatible with GLP-compliant workflows when used with audit-trail-enabled controllers (optional firmware upgrade available). It does not require CE marking for use inside Class II biosafety cabinets or CO₂ incubators per EN 61326-2-1:2013.
Software & Data Management
While the base model features standalone hardware control, optional RS-485 or USB-C connectivity enables integration into centralized lab automation networks. With Thermo Fisher’s optional ShakerLink™ software (v2.3+), users can schedule multi-step protocols, log real-time RPM/temperature traces, export CSV-formatted datasets with ISO 8601 timestamps, and generate PDF reports compliant with 21 CFR Part 11 requirements—including electronic signatures, user access controls, and immutable audit trails. Data retention supports ≥12 months of continuous logging at 10-second intervals on internal flash memory (8 GB).
Applications
- Mammalian cell suspension culture in CO₂-regulated environments (e.g., CHO, HEK293, hybridoma lines)
- Microbial fermentation and bioprocess development under controlled aeration and pH-buffered conditions
- Nucleic acid hybridization (Southern/Northern blotting), ELISA plate washing, and antigen-antibody incubation
- Environmental microbiology studies requiring long-term incubation at elevated CO₂ (e.g., anaerobic digestion modeling)
- Stability testing of biologics and vaccines under accelerated humidity/temperature stress protocols
FAQ
Can this shaker be operated outside a CO₂ incubator?
Yes—the CO₂ resistance is an enhancement, not a limitation. It functions identically as a general-purpose orbital shaker in ambient lab environments.
Is the external controller IP-rated for humid environments?
The controller has an IP54 rating, protecting against dust ingress and water splashes—suitable for placement on incubator exteriors or laminar flow benches.
Does the shaker support ramping or gradient temperature profiles?
No—temperature is held constant during operation. Multi-step thermal profiling requires external environmental chamber integration.
What is the maximum load capacity per platform?
2.5 kg evenly distributed; verified per ASTM E1980-22 static load testing at 300 rpm and 60°C.
Are calibration certificates traceable to NIST standards available?
Factory calibration reports (including temperature and speed verification) are provided with each unit; NIST-traceable calibration services are offered through Thermo Fisher Certified Service Centers.
