TimePower TP350 Portable Dissolved Oxygen Analyzer
| Brand | TimePower |
|---|---|
| Model | TP350 |
| Origin | Beijing, China |
| Manufacturer Type | Direct Manufacturer |
| Origin Category | Domestic (China) |
| Measurement Principle | Clark-type Membrane Electrode (Galvanic) |
| Display | 128×64 LCD, Chinese Interface |
| Measurement Ranges | 0.0–100 µg/L, 100–1000 µg/L, 1.00–20.00 mg/L (auto-ranging) |
| Resolution | 0.1 µg/L (0–100 µg/L), 1.0 µg/L (100–1000 µg/L), 0.01 mg/L (1.00–20.00 mg/L) |
| Accuracy | ±1.0% FS |
| Repeatability | ≤1% |
| Response Time (T90) | <5 min at 25 °C |
| Temperature Compensation Range | 0–60.0 °C |
| Sample Temperature Range | 5–45 °C |
| Ambient Operating Conditions | 5–45 °C, ≤90% RH (non-condensing) |
| Electrode Type | Galvanic DO sensor with Pt cathode and Pb/Al anode, PTFE/PE hydrophobic membrane |
| Built-in Temp Sensor | Pt1000 |
| Power Supply | AC 85–265 V, 45–65 Hz |
| Power Consumption | ≤1 W |
| Dimensions | 285 × 60 × 255 mm |
| Weight | 2.28 kg |
| IP Rating | IP65 |
| Battery Life | Up to 8 hours continuous operation (internal rechargeable battery) |
| Data Storage | Cyclic memory with >10-year data retention after power loss |
| A/D Converter | 24-bit |
| Circuit Architecture | High-integration SMT design with embedded MCU |
Overview
The TimePower TP350 Portable Dissolved Oxygen Analyzer is a field-deployable, galvanic-type electrochemical instrument engineered for high-precision, real-time measurement of dissolved oxygen (DO) in aqueous solutions across trace (µg/L) to low-mg/L concentration ranges. It operates on the Clark electrode principle: molecular oxygen diffuses through a gas-permeable hydrophobic membrane—composed of polytetrafluoroethylene (PTFE) and polyethylene—into an internal electrolyte chamber housing a platinum cathode and lead or aluminum anode. The resulting diffusion-limited current is linearly proportional to the partial pressure of dissolved O₂ at equilibrium, enabling quantitative determination under controlled temperature conditions. Designed for laboratory verification, process monitoring, and field-based environmental or industrial water quality assessment, the TP350 delivers stable, low-drift performance without external polarization voltage—eliminating the need for potentiostatic circuitry and reducing maintenance overhead. Its integrated Pt1000 temperature sensor enables automatic thermal compensation per ISO 5814 and ASTM D888 standards, ensuring metrological traceability across variable ambient and sample conditions.
Key Features
- Triple-range auto-switching detection: 0.0–100 µg/L, 100–1000 µg/L, and 1.00–20.00 mg/L—optimized for ultratrace boiler feedwater, pharmaceutical rinse validation, and municipal effluent compliance.
- Galvanic sensor architecture with imported PTFE/PE composite membrane: T₉₀ response 12 months typical membrane service life under routine calibration).
- 24-bit high-resolution analog-to-digital conversion ensures minimal quantization error and supports repeatable sub-ppb-level discrimination in critical low-oxygen applications.
- Embedded microcontroller platform with ultra-low-power consumption (≤1 W nominal), enabling 8-hour continuous field operation on a single charge—ideal for unattended spot checks or mobile QA/QC workflows.
- IP65-rated enclosure with ergonomic handheld form factor (285 × 60 × 255 mm, 2.28 kg): resistant to dust ingress and low-pressure water jets—suitable for outdoor sampling, wastewater lift stations, and clean utility corridors.
- Non-volatile cyclic memory retains ≥10 years of timestamped measurement records post-power loss; data export via USB or optional RS485 interface supports audit-ready documentation per FDA 21 CFR Part 11 requirements.
Sample Compatibility & Compliance
The TP350 is validated for use with deionized water, boiler feedwater, condensate, ultrapure water (UPW), cooling tower makeup, activated sludge effluents, and pharmaceutical-grade purified water (PW/WFI). It complies with key international methodologies including ISO 5814 (electrochemical determination of dissolved oxygen), ASTM D888 (measuring DO in water), and USP (dissolved oxygen in purified water). The galvanic cell design eliminates zero-current drift associated with polarographic sensors, enhancing long-term stability in GMP-regulated environments where GLP-compliant calibration logs and instrument qualification (IQ/OQ) are mandatory. Membrane replacement and electrolyte refilling follow documented SOPs aligned with manufacturer-recommended intervals—ensuring consistent adherence to method-defined uncertainty budgets.
Software & Data Management
The analyzer features an intuitive Chinese-language menu system rendered on a 128×64 monochrome LCD, eliminating language barriers for domestic technical staff while maintaining full compatibility with international data infrastructure. All measurements are automatically time-stamped and stored with user-configurable logging intervals. Internal memory implements circular overwrite logic—preserving the most recent 10,000+ readings without manual intervention. Data retrieval is supported via direct USB connection to standard PCs; exported CSV files include DO concentration, temperature, date/time stamp, and sensor status flags (e.g., “membrane aging alert”, “low battery”). Optional PC software provides trend visualization, statistical summaries (mean, SD, %RSD), and report generation compliant with ISO/IEC 17025 documentation requirements.
Applications
- Power generation: Monitoring dissolved oxygen in boiler feedwater and condensate systems to prevent oxidative corrosion per ASME PTC 19.11 and EPRI guidelines.
- Pharmaceutical manufacturing: Verifying DO levels in purified water distribution loops and WFI storage tanks during commissioning and routine surveillance.
- Microelectronics: Controlling oxygen contamination in UPW lines feeding photolithography tools and etch processes.
- Environmental monitoring: Field assessment of hypoxic zones in rivers, lakes, and estuaries—supporting EPA Method 360.1 and EU WFD reporting.
- Food & beverage: Validating deaeration efficiency in carbonated beverage fillers and sterile process water systems.
- Academic research: Teaching electrochemical sensor fundamentals and conducting kinetic studies of oxygen mass transfer in bioreactors.
FAQ
What calibration protocols does the TP350 support?
The instrument supports two-point calibration using air-saturated water (100% saturation) and zero-oxygen solution (sodium sulfite or nitrogen-purged water), following ISO 5814 Annex B procedures.
Is the sensor compatible with flowing stream measurements?
Yes—when mounted in the supplied flow-through cell (inlet-bottom, outlet-top configuration), it maintains laminar flow and minimizes boundary layer effects; hard-tube connections are recommended for sub-10 µg/L measurements to prevent atmospheric O₂ permeation.
How often must the membrane and electrolyte be replaced?
Under typical use (daily measurements, 5–40 °C), membrane replacement is advised every 6–12 months; electrolyte refill is required every 3–6 months or after membrane change—always followed by 12–24 hour polarization and recalibration.
Does the TP350 meet regulatory requirements for electronic records?
Yes—its non-volatile memory, tamper-evident timestamps, and structured data export format satisfy foundational elements of FDA 21 CFR Part 11 for electronic records and signatures in regulated industries.
Can the unit operate continuously in humid outdoor environments?
With its IP65 rating and condensation-resistant design, the TP350 is rated for sustained operation in ambient humidity up to 90% RH at 5–45 °C—provided no direct rainfall exposure or submersion occurs.


