TimePower TP350 Portable Fluorescence-Based Dissolved Oxygen Meter
| Brand | TimePower |
|---|---|
| Model | TP350 |
| Type | Portable Dissolved Oxygen Analyzer |
| Measurement Principle | Fluorescence Quenching |
| Range | 0.0–100 µg/L, 100–1000 µg/L, 1.00–20.00 mg/L (auto-ranging) |
| Accuracy | ±1.0% FS |
| Resolution | 0.1 µg/L (0–100 µg/L), 1 µg/L (100–1000 µg/L), 0.01 mg/L (1.00–20.00 mg/L) |
| Repeatability | ≤1% |
| Detection Limit | 0 µg/L ±2 µg/L |
| Response Time (T90) | <5 min at 25°C |
| Temperature Sensor | Pt1000 |
| Temp. Measurement Range | 0.0–99.9°C |
| Temp. Compensation Range | 0.1–80.0°C |
| Sample Temp. Range | 5–80°C |
| Ambient Temp. Range | 5–45°C |
| Humidity | ≤90% RH (non-condensing) |
| Power Supply | AC 220 V ±10%, 50 Hz |
| Power Consumption | <0.5 W |
| Dimensions | 162 × 82 × 33 mm (L×W×H) |
| Weight | ~320 g |
| Display | 128×64 dot-matrix LCD, Chinese interface |
| Data Storage | Cyclic internal memory with >10-year data retention after power loss |
| Battery Life | Up to 8 hours continuous operation on full charge |
Overview
The TimePower TP350 is a portable, fluorescence-based dissolved oxygen (DO) analyzer engineered for high-precision measurement of trace-level dissolved oxygen across ultra-low (ppb) to standard (mg/L) concentration ranges. Unlike traditional electrochemical Clark-type sensors—prone to membrane fouling, electrolyte depletion, and oxygen consumption during measurement—the TP350 employs optical fluorescence quenching technology. In this method, a pulsed blue LED excites a proprietary ruthenium-based luminophore immobilized on a gas-permeable sensing film; molecular oxygen in the sample quenches the resulting red fluorescence proportionally. The phase shift or intensity decay of the emitted signal is measured with high temporal resolution, enabling drift-free, zero-consumption, and maintenance-light operation. Designed specifically for field-deployable water quality assessment, the TP350 meets the operational demands of power plant condensate monitoring, semiconductor ultrapure water (UPW) validation, pharmaceutical WFI (Water for Injection) verification, and environmental surface water surveys where sub-10 µg/L sensitivity and long-term stability are critical.
Key Features
- Triple-range auto-switching detection: 0.0–100 µg/L, 100–1000 µg/L, and 1.00–20.00 mg/L—ensuring optimal resolution across ppb- to ppm-level applications without manual range selection.
- Fluorescence sensor with imported optical membrane head: Delivers rapid T90 response (<5 min at 25°C), exceptional thermal stability (operable up to 80°C sample temperature), and resistance to chemical interference from H₂S, Cl₂, heavy metals, and chlorinated organics.
- High-fidelity signal acquisition: 24-bit analog-to-digital conversion coupled with low-noise front-end circuitry ensures metrological integrity and repeatability ≤1% under controlled conditions.
- Robust embedded architecture: Advanced SMT (surface-mount technology) PCB design, single-chip microcontroller platform, and ultra-low-power management enable 8-hour continuous field operation and >10-year non-volatile data retention—even after complete power loss.
- Intuitive human-machine interface: Chinese-language 128×64 dot-matrix LCD with context-sensitive menu navigation, real-time temperature compensation display, and on-screen calibration prompts reduce operator training burden and minimize procedural error.
Sample Compatibility & Compliance
The TP350 is validated for direct immersion measurement in aqueous matrices including boiler feedwater, turbine condensate, deionized water, purified water (PW), water for injection (WFI), and natural freshwater systems. Its non-consumptive optical principle eliminates polarization errors and flow-dependency issues common in amperometric DO probes—making it suitable for static or low-flow sampling configurations. While not pre-certified for regulatory submission, the instrument’s measurement traceability aligns with ISO 5814:2012 (Water quality — Determination of dissolved oxygen — Electrochemical probe method) and supports compliance workflows referencing ASTM D888 (Standard Test Methods for Dissolved Oxygen in Water) and USP (Total Organic Carbon) when used within validated analytical procedures. Data logging functionality satisfies basic GLP documentation requirements; audit-trail extension requires integration with compliant LIMS or third-party software per FDA 21 CFR Part 11.
Software & Data Management
The TP350 features built-in cyclic memory capable of storing up to 500 timestamped measurement records—including DO value, temperature, date/time stamp, and user-defined sample ID. Memory management is fully automatic: oldest entries are overwritten upon overflow, and all stored data remain intact for over a decade without battery backup. No proprietary PC software is bundled; however, ASCII-formatted export via optional RS232/USB adapter enables seamless import into Excel, LabChart, or ELN platforms. Firmware updates are performed offline using standardized serial protocols—no cloud dependency or vendor lock-in. For regulated environments, raw data files may be archived as immutable .csv logs with SHA-256 checksums to support retrospective review and electronic record integrity per ALCOA+ principles.
Applications
- Thermal power generation: Monitoring dissolved oxygen in high-purity condensate and feedwater circuits to prevent flow-accelerated corrosion (FAC) in carbon steel piping.
- Semiconductor manufacturing: Verifying DO levels <1 ppb in ultrapure water distribution loops prior to wafer rinsing and cleaning stages.
- Pharmaceutical production: Supporting periodic verification of WFI storage and distribution systems per EU GMP Annex 1 and USP .
- Environmental field studies: Rapid profiling of DO stratification in lakes, rivers, and estuaries—especially where low-oxygen hypolimnetic zones require sensitive detection.
- Research laboratories: Serving as a reference-grade portable tool for method development, sensor cross-validation, and teaching fundamental principles of optical oxygen sensing.
FAQ
Does the TP350 require membrane replacement or electrolyte refilling?
No. As a fluorescence-based analyzer, it contains no consumable membranes, cathodes, anodes, or liquid electrolytes—eliminating routine maintenance associated with electrochemical DO sensors.
Can the instrument be calibrated in air-saturated water?
Yes. Two-point calibration is supported: zero-point using sodium sulfite solution (0 µg/L) and span-point using air-saturated water at known temperature and barometric pressure (e.g., 8.26 mg/L at 25°C, 101.3 kPa). Calibration coefficients are stored non-volatily.
Is temperature compensation automatic?
Yes. Integrated Pt1000 sensor continuously measures sample temperature and applies Nernst-corrected compensation across the full 0.1–80.0°C range per ISO 5814 algorithms.
What is the minimum detectable oxygen concentration?
The system achieves a practical detection limit of 0 µg/L ±2 µg/L under stable lab conditions, with reliable quantification down to 0.1 µg/L in the lowest range.
Is the device suitable for seawater measurements?
It is not optimized for high-salinity applications (>35 ppt); salinity correction is not implemented. For marine use, laboratory-grade benchtop analyzers with integrated conductivity-based salinity compensation are recommended.

