WIGGENS Biocen24 High-Speed Microcentrifuge
| Brand | WIGGENS |
|---|---|
| Origin | Germany |
| Model | Biocen24 |
| Centrifuge Type | Benchtop Centrifuge |
| Speed Range | 200–15,000 rpm (10 rpm increments) |
| Max RCF | 21,380 × g (10 × g increments) |
| Speed Accuracy | ±20 rpm |
| Max Capacity | 5 mL × 18 |
| Compatible Tubes | 0.2 mL, 0.5 mL, 1.5 mL, 2 mL, 5 mL microtubes & PCR strips (8 × 4) |
| Temperature Rise at 15,000 rpm | ≤10 °C (rotor only, 60 min runtime) |
| Drive Motor | Brushless DC motor |
| Acceleration/Deceleration Time | 25 s / 25 s |
| Noise Level | ≤64 dB(A) |
| Dimensions (L×W×H) | 364 × 280 × 266 mm |
| Weight | 6 kg |
| Power Supply | AC 110–120 V, 50/60 Hz, 8 A |
| Power Consumption | 200 W |
| Safety Features | Dual interlocked lid, overspeed protection, overtemperature monitoring, imbalance detection, real-time diagnostics |
| Rotor Material | Anodized high-strength aluminum alloy |
| Autoclavable | Yes (121 °C, 20 min, 1.0 kg/cm², unlimited cycles) |
| Biocontainment | Triple high-temp silicone sealing rings |
Overview
The WIGGENS Biocen24 High-Speed Microcentrifuge is a compact, precision-engineered benchtop centrifuge designed for routine and demanding microscale separation tasks in molecular biology, clinical diagnostics, and pharmaceutical quality control laboratories. Operating on the principle of sedimentation under controlled rotational force, the Biocen24 delivers reproducible RCF (relative centrifugal force) up to 21,380 × g at its maximum speed of 15,000 rpm—sufficient for pelleting bacteria, cellular organelles, nucleic acids, and small-volume protein precipitates. Its dual-fan active cooling system employs a three-dimensional air intake architecture to maintain low rotor temperature rise (<10 °C after 60 minutes at full speed), minimizing thermal degradation of thermolabile biomolecules such as RNA, enzymes, and plasmid DNA. The instrument’s rigid chassis, brushless DC motor, and precision-machined conical rotor interface ensure mechanical stability and long-term operational consistency—even during extended runs or frequent start-stop cycles typical in high-throughput workflows.
Key Features
- Active dual-fan cooling with 3D airflow design ensures uniform heat dissipation and limits rotor temperature rise to ≤10 °C during sustained operation at 15,000 rpm.
- Real-time internal chamber temperature display provides continuous thermal monitoring—critical for preserving sample integrity in sensitive applications including RNA isolation and enzyme storage.
- Biological containment rotors feature triple high-temperature silicone sealing rings; bioseal functionality is activated only when the rotor lid is fully tightened, preventing aerosol generation and cross-contamination during high-speed spins.
- High-strength anodized aluminum rotors are certified autoclavable at 121 °C (1.0 kg/cm²) for 20 minutes—supporting GLP/GMP-compliant sterilization protocols without material fatigue or dimensional drift over unlimited cycles.
- Intuitive interface supports rpm/RCF conversion, timed runs (30 s–99 min or continuous), soft-brake deceleration, and instant spin (“pulse”) mode for quick pellet repositioning.
- Comprehensive safety architecture includes dual electromechanical lid locks, overspeed cutoff, real-time imbalance detection, overtemperature shutdown, and embedded diagnostic self-check at power-on and run completion.
Sample Compatibility & Compliance
The Biocen24 accommodates a broad range of microvolume formats via four interchangeable rotor configurations: fixed-angle rotors for 5 mL × 18, 2 mL × 24, 0.5 mL × 36, and PCR strip carriers (8 × 4). With optional adapters, it accepts standard 0.2 mL, 0.5 mL, 1.5 mL, and 2 mL microcentrifuge tubes—including low-retention and filter-based variants used in nucleic acid purification kits. All rotors meet ISO 13485 manufacturing standards and are validated per IEC 61010-1 for laboratory equipment safety. The biocontainment design aligns with CDC/NIH Biosafety Level 2 (BSL-2) operational requirements when used with sealed rotors and appropriate PPE. No external certification is required for routine use in ISO/IEC 17025-accredited testing labs, though audit-ready documentation (including calibration logs and maintenance records) is supported through optional service contracts.
Software & Data Management
While the Biocen24 operates via a standalone front-panel interface, its programmable parameters—including speed, RCF, time, acceleration/deceleration profiles, and audible alerts—are fully traceable via built-in non-volatile memory. Each run stores timestamped metadata (start time, duration, final speed, error codes) accessible through the diagnostic menu. For regulated environments, the device complies with FDA 21 CFR Part 11 principles when paired with WIGGENS’ optional CentriLog™ PC software (sold separately), which enables electronic signature capture, user-level access control, and immutable audit trails—facilitating compliance with GxP, GLP, and internal SOP requirements. All firmware updates are delivered via secure USB protocol and include version-controlled release notes.
Applications
- Molecular biology: Rapid pelleting of PCR products, restriction digests, and column-eluted DNA/RNA; post-lysis clarification of bacterial lysates.
- Clinical microbiology: Concentration of low-abundance pathogens from blood, urine, or CSF prior to culture or molecular detection.
- Protein biochemistry: Small-scale precipitation of recombinant proteins, antibody complexes, or membrane vesicles (e.g., exosomes).
- Pharmaceutical QC: Recovery of sterile-filtered drug formulations in microvials; residual solvent removal from lyophilized intermediates.
- Point-of-care settings: Integration into portable diagnostic platforms requiring rapid, low-footprint sample preparation without refrigerated centrifugation.
FAQ
Is the Biocen24 suitable for BSL-3 applications?
No—the Biocen24 is certified for BSL-2 use only. Its biocontainment rotors prevent aerosol escape under normal operating conditions but do not meet the pressure-differential or HEPA filtration requirements of BSL-3 containment.
Can I autoclave the rotor lid separately?
Yes. Both the rotor body and lid are constructed from autoclavable anodized aluminum and may be sterilized independently at 121 °C, 20 minutes, 1.0 kg/cm²—provided all sealing rings remain intact and undamaged.
Does the instrument support variable acceleration/deceleration rates?
No. The Biocen24 uses fixed 25-second ramp-up and ramp-down profiles optimized for rotor longevity and sample integrity. “Soft brake” mode is enabled by default during deceleration.
What is the minimum detectable imbalance threshold?
The integrated imbalance sensor triggers immediate shutdown if mass asymmetry exceeds 0.5 g across opposing tube positions—a sensitivity level validated per DIN EN 61000-6-3 for electromagnetic compatibility and mechanical safety.
Is remote monitoring or Ethernet connectivity available?
Not natively. Remote operation requires integration with third-party lab automation systems via dry-contact I/O (optional module). Full network connectivity is available only with CentriLog™ + USB-to-Ethernet bridge (accessory).
