Xiangyi H1650-W Benchtop Microcentrifuge

Overview

The Xiangyi H1650-W Benchtop Microcentrifuge is an engineered high-speed centrifugation system designed for routine and precision separation tasks in molecular biology, clinical diagnostics, and microbiology laboratories. Utilizing a brushless DC motor architecture, it delivers stable rotational dynamics with minimal thermal drift and zero carbon dust generation—critical for maintaining sample integrity and instrument longevity. Its operational principle relies on radial acceleration to sediment particles based on mass, density, and shape under controlled gravitational forces (RCF), enabling efficient pelleting of bacterial cells, subcellular organelles, nucleic acids, and protein complexes. With a maximum RCF of 18,360 × g and top speed of 16,500 rpm, the H1650-W meets the performance requirements for standard microcentrifugation protocols including DNA extraction, PCR setup, and cell lysate clarification—without requiring floor-standing infrastructure.

Key Features

• Triple-layer safety system: independent electronic lid lock, overspeed detection, and real-time error monitoring to prevent rotor imbalance or mechanical failure
• Intuitive 4.3-inch capacitive touch display with English-language UI for parameter entry, run status visualization, and error code diagnostics
• Brushless DC motor ensuring low maintenance, extended service life (>20,000 h MTBF), and consistent torque delivery across speed ranges
• Thermally optimized aluminum rotor chamber with passive airflow design, limiting temperature rise to <5 °C above ambient during 15-min continuous operation at max speed
• Seven interchangeable fixed-angle rotors certified for ISO 13485-compliant manufacturing, supporting applications from 0.2 mL PCR strip processing to 5 mL tube centrifugation
• Compliance with IEC 61010-1:2010 safety standards for laboratory electrical equipment, including protection against electric shock, mechanical hazards, and abnormal heat generation

Sample Compatibility & Compliance

The H1650-W accommodates a broad spectrum of microvolume sample containers—including 0.2 mL PCR strips (rotor No.5), 0.5 mL microtubes (rotor No.2), 1.5/2.2 mL Eppendorf-style tubes (rotor No.1), and capillary tubes for hematocrit or serum separation (rotors No.6 & No.7). All rotors are balanced to ISO 21501-4 specifications and undergo dynamic balancing verification prior to shipment. While not explicitly validated for GMP environments, the device supports GLP-aligned documentation practices through timestamped run logs and user-accessible rotor usage counters. It is compatible with common sterilization methods including 70% ethanol wipe-down and UV-C exposure (254 nm, 30 min)—provided rotors are removed and dried prior to irradiation.

Software & Data Management

The H1650-W operates as a standalone instrument without proprietary software dependency. All operational parameters—including speed, time, RCF, and rotor ID—are stored in non-volatile memory and recalled upon power-up. The touch interface retains up to 10 user-defined protocols with editable names and default values. Though no PC connectivity is provided, the system generates ASCII-formatted run reports viewable on-screen post-run, including start/stop timestamps, actual vs. set RCF, and anomaly flags (e.g., “Lid Open Detected”, “Overtemp Warning”). For audit-trail compliance in regulated labs, external data loggers may be interfaced via RS-232 (optional module, order separately) to capture serial output in CSV format suitable for FDA 21 CFR Part 11–aligned review workflows.

Applications

• Routine pelleting of Escherichia coli, Bacillus subtilis, and yeast cultures prior to lysis or genomic DNA isolation
• Clarification of cell lysates and supernatant harvesting in recombinant protein expression workflows
• Concentration of viral particles or exosomes from conditioned media using 5 mL conical tubes
• High-throughput preparation of PCR master mixes with 0.2 mL strip rotors, minimizing cross-contamination risk
• Hematocrit determination and plasma separation from capillary blood samples using calibrated capillary rotors
• Pre-analytical processing in clinical pathology labs for serum/plasma separation prior to ELISA or immunoassay testing

FAQ

What rotor configurations are included with the base H1650-W unit?
The base configuration includes rotor No.1 (12 × 1.5/2.2 mL) only. Additional rotors (No.2–No.7) are available as optional accessories and must be ordered separately with corresponding part numbers.
Is the H1650-W compliant with ISO 15189 or CLIA requirements?
While the instrument meets general electrical safety (IEC 61010-1) and mechanical stability standards, formal ISO 15189 or CLIA validation requires site-specific installation qualification (IQ), operational qualification (OQ), and performance verification per local SOPs—not provided by default.
Can this centrifuge be used for radioactive or biohazardous samples?
Yes—when equipped with sealed rotors and operated inside a certified biosafety cabinet. Users must verify rotor material compatibility (aluminum alloy 6061-T6) with specific chemical agents and adhere to institutional radiation safety protocols for shielding and decontamination.
Does the timer support countdown pause/resume functionality?
No—the timer runs continuously once initiated. Interrupting a run requires manual stop; restart necessitates re-entry of all parameters.
What is the recommended calibration interval for speed and RCF accuracy?
Xiangyi recommends annual verification using a traceable tachometer and RCF calculator per ISO/IEC 17025 guidelines. Calibration certificates are issued by authorized service centers upon request.