YAMATO RE601 Advanced Rotary Evaporator
| Brand | YAMATO |
|---|---|
| Origin | Japan |
| Model | RE601 |
| Capacity | 1 L |
| Rotation Speed | 20–250 rpm |
| Vertical Travel | 130 mm |
| Vacuum Set Range | 0–981 hPa |
| Vacuum Measurement Range | 0–1033 hPa |
| Vacuum Resolution | 1 hPa |
| Hysteresis Setting | 1–50 hPa |
| Vapor Temperature Display Resolution | 0.1 °C or 1 °C (selectable) |
| Power Supply | AC 100–240 V, 50/60 Hz, 1.5 A (unit only) |
| Dimensions (w/d/h) | 828 × 400 × 727 mm (with Glass Assembly A) |
| Weight | ~15 kg (excluding glassware and bath) |
Overview
The YAMATO RE601 Advanced Rotary Evaporator is a precision-engineered laboratory instrument designed for efficient, reproducible solvent removal under reduced pressure. Based on the fundamental principle of rotary evaporation—where simultaneous rotation, heating, and vacuum application lower the boiling point of solvents to accelerate gentle and selective volatilization—the RE601 delivers high process control for purification, concentration, and recovery tasks in synthetic chemistry, natural product isolation, pharmaceutical development, and quality control laboratories. Its compact footprint (compatible with standard fume hood installation), wide-input universal power supply (100–240 V AC), and integrated safety architecture make it suitable for multi-user environments operating under GLP-compliant workflows.
Key Features
- DC brushless motor drive with closed-loop feedback control ensures stable rotational speed across the full range (20–250 rpm), minimizing torque fluctuation and sample splashing—even at low speeds critical for viscous or foaming solutions.
- Motorized vertical lift mechanism (130 mm travel) enables precise, repeatable positioning of the evaporation flask relative to the heating bath; automatic lift-up upon power interruption prevents thermal degradation or bumping.
- Digital vacuum regulation with real-time monitoring (0–1033 hPa range, 1 hPa resolution) and programmable hysteresis (1–50 hPa) supports robust pressure stabilization during dynamic distillation stages.
- Vapor temperature sensing with dual-resolution display (0.1 °C or 1 °C selectable) provides direct insight into vapor-phase thermal conditions—essential for optimizing separation selectivity and avoiding thermal decomposition.
- Multi-mode operation: Free-run, preset-value, timed, proportional, and proportional-timed modes offer flexibility for both routine and method-developed protocols; up to 10 user-defined methods stored per mode (excluding free-run).
- Bilingual interface (Japanese/English) and one-touch parameter recall streamline operator training and cross-regional deployment without configuration overhead.
Sample Compatibility & Compliance
The RE601 accommodates standard 1 L evaporation flasks (e.g., ISO 2781-compliant borosilicate glass assemblies A, B, or C) and integrates seamlessly with external water or oil baths (not included). Its vacuum and thermal control architecture aligns with common laboratory compliance frameworks: vacuum stability supports ASTM E2910-18 (Standard Guide for Solvent Recovery by Rotary Evaporation), while digital logging capability (when paired with compatible YAMATO bath controllers or third-party SCADA systems) facilitates audit-ready data capture per FDA 21 CFR Part 11 requirements when implemented with appropriate electronic signature and audit trail configurations. All electrical components meet IEC 61010-1 safety standards for laboratory equipment.
Software & Data Management
While the RE601 operates as a standalone instrument with embedded firmware, its digital I/O ports (RS-232 or optional analog outputs) allow integration into centralized lab automation platforms. Parameter settings—including rotation speed, vacuum setpoint, vapor temperature target, and timing profiles—are retained in non-volatile memory. When connected to a compliant bath system (e.g., YAMATO SB-1100 series), bidirectional联动 control enables synchronized shutdown or temperature hold upon vacuum deviation or motor fault—enhancing method robustness and reducing manual intervention. Data export requires external logging via serial communication; no proprietary cloud platform or vendor-hosted software is required.
Applications
- Solvent removal from reaction mixtures in organic synthesis and catalysis research.
- Concentration of heat-sensitive biomolecules (e.g., peptides, oligonucleotides) under controlled vapor temperature.
- Purification of natural extracts prior to HPLC or GC analysis.
- Recovery and recycling of high-purity solvents in QC/QA labs adhering to ISO/IEC 17025 documentation standards.
- Method transfer between R&D and pilot-scale production, leveraging consistent vacuum and rotational repeatability.
FAQ
What is the maximum recommended flask size for the RE601?
The RE601 is optimized for 1 L evaporation flasks; larger volumes may compromise rotational stability and vacuum integrity.
Does the RE601 include a heating bath?
No—the unit does not include a heating bath; it is designed for use with external water or oil baths (e.g., YAMATO SB-series or equivalent ISO-compliant models).
Can vacuum and rotation parameters be logged externally?
Yes—via RS-232 interface or analog output signals, enabling connection to data acquisition systems for GLP-aligned recordkeeping.
Is the RE601 compatible with corrosive solvents like chlorinated hydrocarbons?
When used with chemically resistant glassware (e.g., borosilicate 3.3) and appropriate vacuum pump oil/filters, it supports common organic solvents; consult YAMATO’s chemical compatibility chart for specific recommendations.
What safety certifications does the RE601 carry?
It complies with IEC 61010-1:2010 for electrical safety and meets EMC requirements per IEC 61326-1:2013; CE marking is applied for EU market conformity.
