Yoyilab LRH-300F Biochemical Incubator

Overview

The Yoyilab LRH-300F Biochemical Incubator is a precision-engineered, dual-mode (heating and refrigeration) environmental chamber designed for stable, long-term cultivation and preservation of microorganisms—including bacteria, yeasts, molds, and fungi—under controlled thermal conditions. Built upon a robust compressor-based cooling system combined with PID-regulated resistive heating, the unit delivers bidirectional temperature control across a broad operational range of 0–65°C. Its thermally optimized double-door structure, mirror-finish stainless-steel interior, and precisely calibrated airflow distribution ensure high spatial uniformity (±1.5°C at 25°C) and minimal thermal disturbance during observation or sample access. The incubator complies with fundamental design principles outlined in ISO 13408-1 (aseptic processing environments) and supports GLP-aligned workflows through traceable temperature logging and parameter retention functions.

Key Features

• Microprocessor-controlled PID temperature regulation with 0.1°C resolution and adaptive tuning for minimized overshoot and rapid stabilization
• Compressor-driven refrigeration system with eco-friendly R134a refrigerant (non-ozone-depleting, F-series designation)
• Double-glazed, insulated observation door with low-emissivity coating to reduce heat transfer and maintain internal stability during visual monitoring
• Electro-polished 304 stainless-steel interior chamber with radius-corner geometry for seamless cleaning and microbial contamination control
• Adjustable stainless-steel shelving (standard configuration: 3 shelves), load-rated for uniform weight distribution up to 15 kg per shelf
• Intelligent power-loss recovery: automatically restores pre-interruption setpoints and runtime upon power resumption; retains all user-defined parameters in non-volatile memory
• Over-temperature deviation alarm with independent hardware cutoff circuitry (fail-safe thermal limiter) meeting IEC 61000-4-2 immunity requirements
• 5.7-inch TFT LCD interface supporting multi-parameter real-time display: setpoint, actual chamber temperature, elapsed time, remaining hold duration, and alarm status

Sample Compatibility & Compliance

The LRH-300F accommodates standard microbiological containers including Petri dishes (up to 150 mm diameter), culture flasks (up to 2 L), test tubes (in rack configurations), and multi-well plates. Its chamber geometry (interior W×D×H: 580 × 540 × 950 mm) permits flexible stacking and orientation of stacked trays without impeding convective air circulation. The unit is validated for use in BOD5 incubation per ASTM D5210 and EPA Method 405.1, and meets ambient operating constraints specified in USP for stability-indicating equipment used in pharmaceutical microbiology. All electrical components conform to CE marking directives (2014/30/EU EMC, 2014/35/EU LVD), and the enclosure satisfies IP20 ingress protection per IEC 60529.

Software & Data Management

While the base LRH-300F operates via embedded firmware, optional RS485 communication (Modbus RTU protocol) enables integration into centralized lab monitoring systems. When paired with the optional data acquisition software package (sold separately), users gain access to time-stamped temperature logs compliant with FDA 21 CFR Part 11 requirements—including electronic signatures, audit trails, and immutable record export (CSV/Excel). Optional embedded thermal printer provides hard-copy verification of calibration events and daily operational checks. Firmware supports configurable alarm thresholds, scheduled start/stop cycles (1–9999 min), and password-protected parameter editing to enforce SOP adherence.

Applications

• Biochemical oxygen demand (BOD) testing in environmental water quality laboratories
• Microbial enumeration and isolation in public health and food safety testing labs
• Fungal sporulation studies and mycotoxin production assays under defined thermal regimes
• Short-term storage of clinical isolates and reference strains prior to subculturing or cryopreservation
• Plant tissue culture initiation and callus maintenance where precise ambient temperature modulation is required
• Stability assessment of diagnostic reagents and enzyme-based assay kits across accelerated aging profiles

FAQ

What is the maximum ambient temperature at which the LRH-300F maintains full cooling capacity?

The unit is rated for continuous operation in ambient environments between +5°C and +30°C. At 30°C ambient and 4°C setpoint, compressor duty cycle increases but full specification compliance is maintained.
Does the incubator support programmable temperature ramps or multi-step profiles?

The standard configuration features single-setpoint control with timer hold function. Multi-segment programming requires the optional external controller (part #LRH-PC1000), sold separately.
Is validation documentation (IQ/OQ/PQ protocols) available for GMP environments?

Yoyilab provides generic OQ templates aligned with ISO/IEC 17025; site-specific PQ execution and certification must be performed by qualified third-party metrology providers.
Can the interior shelves be removed for decontamination or large-volume vessel placement?

Yes—shelves are fully detachable and compatible with autoclaving (up to 121°C, 2 bar); load-bearing posts remain fixed to maintain structural integrity.
What safety certifications does the LRH-300F carry for international shipment?

The unit carries CE marking (EMC & LVD), RoHS 2011/65/EU compliance, and factory-issued Declaration of Conformity. UL/cUL listing is not included but can be pursued via authorized North American certification bodies upon request.