Zhengxin EPF-200ml Gas-Connected Synthesis Reactor

Overview

The Zhengxin EPF-200ml Gas-Connected Synthesis Reactor is a precision-engineered, micro-scale batch reactor designed for controlled gas-phase reactions under elevated pressure and temperature. Based on the Couette-type sealed vessel architecture, it employs a threaded 304 stainless steel housing with a chemically inert PTFE (polytetrafluoroethylene) liner—ensuring compatibility with corrosive reagents, strong acids/bases, and reactive gaseous species such as H₂, O₂, CO, NH₃, or Cl₂. The reactor integrates standardized gas handling interfaces—including inlet/outlet needle valves, vacuum/exhaust ports, and pressure monitoring—enabling safe, repeatable operation in inert, reducing, or oxidizing atmospheres. Its modular design supports both static and dynamic gas exchange protocols, making it suitable for catalytic hydrogenation, hydrothermal synthesis, gas-solid heterogeneous catalysis, and solvent-free oxidative transformations. All mechanical seals conform to ISO 2852 and ASME B16.20 specifications for sanitary and high-integrity fluid connections.

Key Features

• Robust 304 stainless steel main body with electropolished interior surface finish (Ra ≤ 0.4 µm) for enhanced corrosion resistance and cleanability
• Standard PTFE liner rated for continuous use up to 240 °C; optional PPL (perfluoroalkoxy alkane) liner available for extended thermal stability up to 280 °C
• Dual-ferrule compression fittings (1/4″ or 1/8″) on all gas ports—compatible with standard Swagelok® and Parker A-LOK® tubing systems
• Integrated stainless steel Bourdon-tube pressure gauge (0–10 MPa range, Class 1.6 accuracy) with front-mounted dial for real-time process monitoring
• 316L stainless steel thermowell accommodating standard K-type or Pt100 RTD probes, enabling direct immersion temperature measurement within the reaction zone
• Pressure-rated rupture disc safety system (set point adjustable per application, default 6 MPa) compliant with PED 2014/68/EU requirements
• Quick-release threaded closure mechanism enabling tool-free disassembly and liner replacement in under 90 seconds
• Optional accessories include stainless steel sampling valve, magnetic stirrer coupling port, and jacketed heating/cooling interface

Sample Compatibility & Compliance

The EPF-200ml reactor accommodates liquid volumes from 30 mL to 135 mL (recommended fill ratio: 30–65% of liner capacity) to ensure adequate headspace for gas expansion and safe pressure development. It is validated for use with organic solvents (e.g., DMF, THF, ethanol), aqueous electrolytes, supercritical CO₂ mixtures, and halogenated reagents. All wetted components meet USP Class VI biocompatibility standards and comply with FDA 21 CFR Part 11 requirements when paired with audit-trail-enabled data acquisition software. The reactor design adheres to ISO 14001 environmental management principles and supports GLP/GMP-aligned documentation workflows through traceable calibration records and material certification (EN 10204 3.1).

Software & Data Management

While the base unit operates manually, it is fully compatible with third-party process control systems via analog 4–20 mA pressure and temperature signal outputs. When integrated with Zhengxin’s optional ZxControl™ LabHub interface (sold separately), users gain access to time-stamped logging, alarm thresholds, automated pressure ramping profiles, and electronic signature support aligned with 21 CFR Part 11 Annex 11 guidelines. Raw sensor data exports to CSV or Excel formats for statistical analysis in JMP, Minitab, or Python-based chemometrics pipelines.

Applications

• Catalytic hydrogenation of unsaturated organic compounds under controlled H₂ partial pressure
• Hydrothermal synthesis of metal–organic frameworks (MOFs) and nanocrystalline oxides
• Gas-phase photochemical reactions using quartz-lined variants (custom order)
• Accelerated aging studies of battery electrolytes under CO₂ or O₂ atmosphere
• High-pressure enzymatic reactions requiring strict anaerobic conditions
• Teaching laboratories: demonstration of Le Chatelier’s principle, equilibrium constants (K_p), and Arrhenius kinetics

FAQ

What is the maximum recommended fill volume for the EPF-200ml reactor?

The optimal working volume is 60–135 mL (30–65% of total liner capacity) to maintain sufficient vapor space and prevent over-pressurization during exothermic or gas-evolving reactions.

Can the PTFE liner be replaced in situ without specialized tools?

Yes—the liner is retained solely by mechanical interference fit and can be removed and reinstalled manually after loosening the main cap ring; no adhesives or fasteners are used.

Is the reactor suitable for vacuum distillation applications?

It supports vacuum levels down to 0.1 kPa (absolute) and is routinely used for degassing, solvent removal, and low-pressure crystallization—provided condensation traps and cold finger adapters are externally configured.

Does the pressure relief device require recalibration or periodic replacement?

Rupture discs are single-use, non-resettable safety elements; each disc carries a certified burst tolerance (±3% at 23 °C) and must be replaced after activation or every 12 months under active service per ISO 4126-2.

Are CE or UL certifications available for this model?

The EPF series carries CE marking under the Machinery Directive 2006/42/EC and PED 2014/68/EU; UL listing is available upon request for North American distribution channels with additional testing protocol execution.