ZONWON DP25 Precision Automated Liquid Handler (0.1% Accuracy)

Overview

The ZONWON DP25 Precision Automated Liquid Handler is an engineered solution for high-reproducibility liquid dispensing and volumetric preparation in analytical, quality control, and research laboratories. Designed around a precision motor-driven syringe pump architecture, the DP25 operates on positive displacement principles—ensuring consistent delivery across viscous, volatile, corrosive, and low-surface-tension liquids without reliance on air displacement or piston seal compression alone. Its core application domain includes quantitative dilution, fixed-concentration solution preparation, serial transfer, and gravimetrically guided formulation—particularly where manual pipetting with rubber bulbs and glass graduated pipettes introduces operator-dependent variability, exposure risk, and throughput bottlenecks. The system meets foundational operational requirements for GLP-compliant environments through traceable volume control, non-contact operation, and standardized workflow execution.

Key Features

• Motorized single-channel dispensing with programmable volume selection from 1 to 25 mL (extendable to 50 mL using optional syringe cartridges)
• High-accuracy volumetric control: ±0.1% relative accuracy at full scale, validated per ISO 8655-5 guidelines for piston-type liquid handlers
• Integrated 7-inch capacitive touchscreen interface with intuitive icon-based navigation—no specialized training required
• Gravimetric integration capability: real-time RS232/USB communication with certified laboratory balances (e.g., METTLER TOLEDO, SARTORIUS, OHAUS) for automatic mass-to-volume conversion and closed-loop concentration adjustment
• Chemical-resistant fluid path constructed from PTFE-coated stainless steel, chemically inert ceramics, and fluoropolymer seals—validated for continuous use with 96% sulfuric acid, concentrated NaOH/KOH solutions, acetone, chloroform, and acetonitrile
• Programmable post-dispense dwell time and controlled final-drop management to ensure complete fluid transfer and minimize carryover
• Onboard auto-calibration routine with built-in reference weight verification mode for daily performance checks
• Modular expansion support: DP25+ variants accommodate 12-position rotating sample racks (30/50/75 mL vial compatibility) or direct balance synchronization for unattended multi-step preparation protocols

Sample Compatibility & Compliance

The DP25 is validated for handling aqueous, organic, acidic, alkaline, and mixed-phase solutions typical in polymer analysis (e.g., phenol/tetrachloroethane dissolution), pharmaceutical excipient preparation, food additive standardization, and clinical reagent formulation. Its sealed drive mechanism and non-contact dispensing eliminate aerosol generation and skin contact during operations involving hazardous substances. While not CE-marked or FDA 510(k)-cleared as a medical device, the instrument conforms to IEC 61010-1 safety standards for laboratory electrical equipment and supports audit-ready documentation practices aligned with ISO/IEC 17025 and ASTM E2915–22 for volumetric instrument qualification. Routine verification follows manufacturer-recommended intervals and may be integrated into laboratory SOPs for GLP/GMP workflows.

Software & Data Management

The embedded firmware supports user-defined method storage (up to 100 protocols), timestamped operation logs, and exportable CSV records of dispense events—including volume setpoint, actual delivered volume (if external balance feedback is enabled), date/time stamp, and operator ID. No proprietary software installation is required; configuration and diagnostics are fully accessible via the onboard UI. For labs operating under 21 CFR Part 11 compliance mandates, third-party electronic lab notebook (ELN) systems can ingest DP25-generated log files via standard USB mass storage or network file sharing—enabling secure archiving, electronic signatures, and change-control tracking when paired with validated middleware.

Applications

• Preparation of calibration standards and QC reference materials in environmental testing (e.g., EPA Method 525.3, ISO 17993)
• Automated dissolution media preparation in pharmaceutical development (USP )
• Reagent batching for ELISA, PCR master mix assembly, and immunoassay workflows
• Polymer intrinsic viscosity determination requiring precise solvent dosing into capillary viscometers
• Food allergen extraction and dilution protocols compliant with AOAC 2012.01 and EN ISO 22866
• Standard addition workflows in ICP-MS and AAS sample introduction systems

FAQ

What is the minimum dispense volume supported by the DP25?
The instrument achieves reliable delivery down to 1 mL with ≤0.1% relative error at 25 mL; performance below 1 mL is not specified and should be verified experimentally for critical applications.
Can the DP25 handle viscous solutions such as glycerol or polymer melts?
Yes—when used with appropriate syringe cartridge selection and adjusted aspiration/dispense speed profiles. Viscosity compensation is not automated but can be managed via custom program timing parameters.
Is remote control or PC integration supported?
Native Ethernet or Wi-Fi connectivity is not included; however, USB HID emulation allows basic keyboard-emulation triggering, and RS232 enables ASCII command control for integration into custom LIMS or automation frameworks.
How often does the system require recalibration?
Annual calibration is recommended; daily verification using certified weights and water density correction is advised for regulated environments.
Are disposable syringe cartridges supplied with the instrument?
Two 25 mL and two 50 mL PTFE-lined syringe cartridges are included as standard; additional cartridges are available as consumables (part numbers ZS-25P and ZS-50P).