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| Brand | Thermo Fisher |
|---|---|
| Origin | USA |
| Manufacturer Type | Authorized Distributor |
| Origin Category | Imported |
| Model | Q Exactive HF-X Hybrid Quadrupole-Orbitrap |
| Instrument Type | Orbitrap-Based LC-MS/MS |
| Application Scope | Universal (Proteomics, Metabolomics, Biopharma, Small Molecule Analysis) |
| Max Resolving Power | 240,000 (FWHM) at m/z 200 |
| Scan Speed | Up to 40 Hz (MS/MS) |
| Ionization Compatibility | Electrospray (ESI), Atmospheric Pressure Chemical Ionization (APCI), optional Nano-ESI |
| Acquisition Modes | Data-Dependent Acquisition (DDA), Data-Independent Acquisition (DIA), Parallel Reaction Monitoring (PRM), Intact Protein Mode, High Mass Range (HMR) Mode |
| Software Platform | Thermo Scientific™ Compound Discoverer™, Proteome Discoverer™, and xCalibur™ v4.5+ with FDA 21 CFR Part 11 compliance support |
| Brand | Agilent Technologies |
|---|---|
| Origin | Canada |
| Model | 6550A |
| Instrument Type | Quadrupole-Time-of-Flight (Q-TOF) |
| Mass Range | 100–10,000 m/z |
| Sensitivity | 4500:1 (S/N, 1 pg injected) |
| Resolution | 45,000 (FWHM at m/z 922) |
| Mass Accuracy | ≤1 ppm (internal calibration) |
| Acquisition Rate | Up to 50 spectra/sec |
| Dynamic Range | >5 orders of magnitude (within single spectrum) |
| Brand | SCIEX |
|---|---|
| Origin | USA |
| Model | AB SCIEX 5500 QTRAP |
| Instrument Type | Triple Quadrupole (QqQ) with Linear Ion Trap Capability |
| Mass Range | 5–1250 m/z |
| Sensitivity | 50 fg reserpine (ESI positive mode) |
| Resolution | 0.7 amu |
| Scan Speed | ≥12,000 amu/s |
| Mass Stability | ≤±0.1 Da/24 h |
| Polarity Switching Time | ≤50 ms |
| Max LC Pressure | 15,000 psi |
| Column Temperature Range | 5–65 °C |
| Signal-to-Noise Ratio (S/N) | >500:1 |
| Brand | Thermo Fisher |
|---|---|
| Origin | Canada |
| Manufacturer Type | Authorized Distributor |
| Origin Category | Imported |
| Model | Orbitrap Fusion |
| Instrument Type | Orbitrap-based Hybrid Mass Spectrometer |
| Application Scope | Universal |
| Mass Range | 100–6000 m/z |
| Sensitivity | S/N ≥ 100:1 (50 fg/µL reserpine) |
| Resolution | Up to 500,000 (at m/z 200, FWHM) |
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