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Thermo Fisher Scientific Electron Microscopy

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BrandThermo Fisher Scientific
OriginCzech Republic
Manufacturer TypeOriginal Equipment Manufacturer (OEM)
Origin CategoryImported Instrument
ModelKrios G4 Cryo-TEM
Price RangeUSD 5.2–5.8 million (estimated FOB)
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BrandThermo Fisher Scientific
OriginNetherlands
ManufacturerThermo Fisher Scientific
Import StatusImported
ModelQuattro
ConfigurationFloor-standing (Conventional High-Performance SEM)
Electron SourceCold Field Emission Gun (CFEG)
Vacuum ModesHigh Vacuum / Low Vacuum / Environmental SEM (ESEM™)
Detector CompatibilityIn-lens SE, Solid-state BSE, STEM-in-SEM, Cathodoluminescence (CL), EDS (up to 3 detectors), EBSD, WDS
StageMotorized 5-axis eucentric stage with ±105° tilt
Temperature Range (In-situ)–165°C to 1400°C (with optional cryo/thermal stages)
Software PlatformThermo Scientific™ Avizo™-integrated SmartSEM™ with Python-based AutoScript API
ComplianceDesigned for GLP/GMP environments
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BrandThermo Fisher Scientific
OriginImported
Manufacturer TypeOriginal Equipment Manufacturer (OEM)
ModelAquilos 2 Cryo-FIB
Price RangeUSD 1.3–2.0 million (FOB)
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BrandThermo Fisher
OriginGuangdong, China
Manufacturer TypeOEM Manufacturer
Regional ClassificationDomestic (China)
ModelApreo ChemiSEM
QuotationUpon Request
Instrument Form FactorFloor-Standing
Electron Source TypeThermal Field-Emission Gun (TFEG)
Microscope ClassUltra-High-Resolution Field-Emission SEM
Secondary Electron Resolution0.7 nm @ 30 kV
Magnification Range29× to 200,000×
Accelerating Voltage Range200 V – 30 kV
Backscattered Electron Resolution0.8 nm @ 1 kV
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BrandThermo Fisher
OriginNetherlands
Manufacturer TypeOriginal Equipment Manufacturer (OEM)
Origin CategoryImported
ModelAxia ChemiSEM
Instrument TypeFloor-Standing Conventional SEM
Electron SourceTungsten Filament
Secondary Electron Resolution3 nm @ 30 kV, 8 nm @ 3 kV
Accelerating Voltage0.2–30 kV
Backscattered Electron Imaging CapabilityIntegrated
Elemental Analysis IntegrationOn-platform EDS (Energy-Dispersive X-ray Spectroscopy)
Sample Weight CapacityUp to 10 kg
Automation LevelFully Automated Beam Alignment, Smart User Guidance, Undo Functionality
ComplianceDesigned for GLP/GMP environments with audit-trail-ready software architecture
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BrandThermo Fisher Scientific
ModelIliad
TypeSpherical Aberration-Corrected Scanning/Transmission Electron Microscope (S/TEM)
Integrated SpectroscopyDual-mode EELS (including XEELS™ up to 30 keV) and Energy-Filtered Imaging
DetectorsZebra EELS Detector, NanoPulser Electrostatic Beam Blanking (1 MHz, ≤10 ns pulse width), Optional Dual-X/Super-X/Ultra-X EDX
SoftwareVelox™ (S/TEM, EDX, EELS acquisition & analysis), Autoscript™ TEM (Python-based automation, AI-integrated workflow control)
ComplianceDesigned for GLP/GMP-aligned labs
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BrandThermo Scientific
OriginNetherlands
ModelArctis
Ion SourcesXe⁺, O⁺, Ar⁺
Sample CapacityUp to 12 cryo-grids (TomoGrids/AutoGrids)
Integrated iFLMYes
Vacuum SystemUltra-high vacuum cryo-chamber
Cooling ArchitectureDual-stage cryo-shielding with braided cryo-sleeve
ComplianceDesigned for GLP/GMP-aligned cryo-EM workflows, compatible with FDA 21 CFR Part 11–ready software environments
Biocontainment OptionHigh-temperature decontamination mode for BSL-3 labs
Stage Tilt Range±90° (180° total) CompuStage™
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BrandThermo Fisher
OriginNetherlands
Manufacturer TypeOriginal Equipment Manufacturer (OEM)
Origin CategoryImported
ModelSpectra S/TEM
Price RangeUSD 4.2–4.9 million (approx.)
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BrandThermo Fisher Scientific
OriginImported
Manufacturer TypeOriginal Equipment Manufacturer (OEM)
ModelVolumescope 2
Instrument TypeFloor-standing SEM
Electron SourceCold Field Emission Gun (CFEG)
Accelerating Voltage1.0–30 kV
Vacuum ModesHigh Vacuum (HiVac) and Low Vacuum (LoVac) with VSDBS detector
Z-axis Optical Sectioning ResolutionUp to 10 nm
Sample HandlingAutomated ultramicrotome integration for seamless transition between conventional SEM and SBFI/AT workflows
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BrandThermo Fisher Scientific
OriginImported (Netherlands/USA manufacturing site)
Manufacturer TypeOriginal Equipment Manufacturer (OEM)
ModelTalos L120C TEM
Price RangeUSD 1.9–2.5 million (FOB)
Accelerating Voltage120 kV
Camera System4k × 4k Ceta CMOS (16 MP), optional SmartCam™ digital search/overview camera
Vacuum SystemFully automated dual-stage turbomolecular pumping with rapid lock recovery (<60 s after air exposure)
AutomationAuto-gun alignment, auto-focus, auto-stigmator, EPU-integrated cryo-TEM workflow
Software PlatformThermo Scientific TEM Imaging & Analysis (TIA) v5.x with GLP-compliant audit trail and 21 CFR Part 11-ready user management
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BrandThermo Fisher Scientific
OriginImported (Netherlands/USA manufacturing site)
Manufacturer TypeOriginal Equipment Manufacturer (OEM)
ModelTalos F200C TEM
Accelerating Voltage Range20–200 kV
DetectorIntegrated 1600 × 1600 CMOS Direct Detection Camera
Lens ConfigurationConstant-Power C-Twin Objective Lens
Optional StagePiezo-Driven High-Stability Specimen Stage
ComplianceDesigned for GLP/GMP-compliant labs
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BrandThermo Fisher Scientific
OriginCzech Republic
Manufacturer TypeOriginal Equipment Manufacturer (OEM)
Origin CategoryImported
ModelTalos F200X
Price RangeUSD 2.1–2.8 million (FOB)
Accelerating Voltage200 kV
Magnification Range50× to 1,500,000×
Point Resolution≤0.12 nm (TEM), ≤0.16 nm (STEM)
EDS DetectorSuper-X G3 with 4 silicon drift detectors
CameraCeta 16M CMOS, 16-megapixel, 4k × 4k, 25 fps at full resolution
StagePiezo-driven high-precision motorized stage with sub-nanometer stability
Optional In Situ CapabilitiesHeating, cooling, electrical biasing, and gas/liquid environmental holders
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BrandThermo Fisher Scientific
OriginGuangdong, China
Manufacturer TypeOriginal Equipment Manufacturer (OEM)
Regional ClassificationDomestic Production
ModelApreo
Instrument TypeFloor-Model High-Performance SEM
Electron Gun TypeCold Field Emission (CFEG)
Microscope ClassUltra-High-Resolution Field-Emission SEM
Secondary Electron Resolution1.0 nm at 1 kV (in-lens detection, no beam deceleration or monochromator)
Accelerating Voltage Range200 V – 30 kV
Backscattered Electron Resolution≤1.5 nm at 30 kV (T1 in-lens BSE detector)
Chamber ConfigurationTriple EDS/WDS port capability
Vacuum SystemDual-mode (High Vacuum & Variable Pressure up to 500 Pa)
Software PlatformxT User Interface with SmartSCAN™, Drift Compensation Frame Integration (DCFI), and Charge Filtering Algorithms
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BrandThermo Fisher Scientific
OriginCzech Republic
Manufacturer TypeOriginal Equipment Manufacturer (OEM)
Origin CategoryImported Instrument
ModelHelios 5 Laser PFIB
Price RangeUSD 920,000 – 1,315,000
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BrandThermo Scientific
OriginNetherlands
ModelGlacios 2
Accelerating Voltage200 kV
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BrandThermo Scientific
OriginNetherlands
ModelSelectris / Selectris X
Price RangeUSD 65,000 – 130,000
CompatibilityKrios™ and Glacios™ Cryo-TEM Platforms
Detector IntegrationFully Compatible with Falcon™ 4 Direct Electron Detector
Energy Slit Width<10 eV (Zero-Loss Filtering)
Application FocusCryo-EM Single-Particle Analysis (SPA) and Cryo-Electron Tomography (Cryo-ET)
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BrandThermo Fisher Scientific
OriginCzech Republic
Manufacturer TypeOriginal Equipment Manufacturer (OEM)
Origin CategoryImported
ModelScios
Price RangeUSD 920,000 – 1,315,000 (based on EUR/USD exchange and typical landed cost for high-end FIB-SEM systems)
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BrandThermo Fisher Scientific
OriginCzech Republic
Manufacturer TypeOriginal Equipment Manufacturer (OEM)
Origin CategoryImported
ModelHelios NanoLab DualBeam™
Price RangeUSD 1.3M – 1.9M
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BrandThermo Fisher
OriginImported (Non-China)
Manufacturer TypeOriginal Equipment Manufacturer (OEM)
Electron Gun TypeCold Field Emission
ModelPrisma E SEM
Vacuum ModesHigh Vacuum, Low Vacuum, Environmental SEM (ESEM) Mode
Sample Chamber CapacityUp to 18 samples per load
Detector FlexibilityMultiple detector options including SE, BSE, EDS, and optional STEM-in-SEM
Software IntegrationColorSEM real-time elemental mapping, image navigation, customizable UI with Undo/Redo functionality
ComplianceDesigned for GLP/GMP environments
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BrandThermo Fisher Scientific
OriginCzech Republic
Manufacturer TypeOriginal Equipment Manufacturer (OEM)
Origin CategoryImported
ModelVerios XHR
Instrument TypeFloor-standing / Conventional High-Performance SEM
Electron SourceCold Field Emission Gun (CFEG)
Accelerating Voltage Range1–30 kV
Secondary Electron Resolution<0.7 nm at 1 kV, <0.4 nm at 30 kV (as specified in Thermo Fisher technical documentation)
Backscattered Electron Resolution<1.5 nm at 30 kV
Sample Chamber DimensionsØ340 mm × H280 mm
Maximum Sample Size200 mm wafer or 100 mm × 100 mm × 50 mm bulk specimen
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BrandThermo Scientific
OriginNetherlands
Manufacturer TypeAuthorized Distributor
Origin CategoryImported
ModelTundra
Accelerating VoltageFixed 100 kV
Maximum Magnification650,000×
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