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Agilent Certified Refurbished 1100 Series Liquid Chromatograph

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Brand Agilent Technologies
Origin USA
Manufacturer Type Original Equipment Manufacturer (OEM)
Origin Category Imported Instrument
Model 1100
Warranty 1 Year
Product Category Chromatography System
Instrument Type Liquid Chromatograph
Refurbishment Standard Agilent Certified Refurbished

Overview

The Agilent Certified Refurbished 1100 Series Liquid Chromatograph is a fully validated, factory-reconditioned high-performance liquid chromatography (HPLC) system originally introduced by Agilent Technologies in 1995. As one of the most widely deployed HPLC platforms globally—with over 50,000 units in active operation across pharmaceutical, academic, clinical, and industrial laboratories—the 1100 Series exemplifies robust architecture, proven separation performance, and long-term operational stability. This certified refurbished unit undergoes comprehensive restoration at Agilent’s authorized refurbishment centers under the same engineering oversight responsible for original design and manufacturing. Each instrument is restored to meet original factory specifications for hydraulic integrity, gradient accuracy, dwell volume consistency, detector linearity (UV-Vis), and pump pulsation control—ensuring metrological equivalence to new-system baseline performance. The system supports isocratic and gradient elution, column oven temperature regulation, autosampler precision injection, and dual-wavelength UV detection, making it suitable for routine quality control (QC), method validation, stability-indicating assays, and preparative-scale fraction collection.

Key Features

  • Factory-certified refurbishment performed exclusively by Agilent-trained engineers using OEM diagnostic tools and calibration standards.
  • Complete mechanical, electrical, and functional verification including pressure testing, flow accuracy assessment (±1% RSD), gradient composition verification, and detector wavelength calibration (±1 nm).
  • New housing, front panel interface, power supply unit, and firmware pre-loaded with latest compatible software revision (e.g., ChemStation Rev. A.10.x or later).
  • Full compatibility with Agilent’s current-generation consumables—including G1312B quaternary pumps, G1313A autosamplers, G1316A column ovens, and G1314B UV-Vis detectors—as well as legacy modules from the 1100/1200 platform family.
  • One-year limited warranty covering parts and labor, aligned with Agilent’s standard new-instrument warranty terms and service response SLAs.
  • Eligibility for Agilent Service Agreements (including Preventive Maintenance, Extended Warranty, and 24/7 remote diagnostics support) and full access to Agilent’s global spare parts logistics network.

Sample Compatibility & Compliance

The Agilent 1100 Series accommodates a broad range of sample matrices—including small-molecule APIs, peptides, oligonucleotides, natural product extracts, and environmental contaminants—when paired with appropriate reversed-phase, HILIC, ion-exchange, or size-exclusion columns (2.1–4.6 mm ID, 30–250 mm length). It complies with critical regulatory expectations for analytical instrumentation used in GLP and GMP environments: data integrity features include audit-trail-enabled software (when operated with compliant ChemStation configurations), electronic signature support per FDA 21 CFR Part 11 (with appropriate system setup), and traceable calibration records generated during refurbishment. All refurbished units ship with documented IQ/OQ protocols executed per Agilent’s internal qualification framework, aligning with ISO/IEC 17025 principles and supporting user-defined PQ execution.

Software & Data Management

Operates natively with Agilent ChemStation for LC and LC/MS systems (versions A.08.x through A.10.x), offering validated sequence control, peak integration, calibration curve generation, and report export in PDF, CSV, and XML formats. Data files (.D folders) maintain full backward compatibility with newer OpenLab CDS versions via migration utilities. Audit trails record all method edits, sequence modifications, and result reprocessing events with timestamps and operator IDs. Raw data storage adheres to ALCOA+ principles when deployed on secure, backed-up network drives; optional integration with Agilent’s OpenLab ECM enables role-based access control and automated backup scheduling.

Applications

  • Routine pharmaceutical QC testing (assay, related substances, dissolution) per USP , EP 2.2.46, and JP 6.01 methodologies.
  • Method development and transfer for stability studies under ICH Q1–Q5 guidelines.
  • Academic and contract research applications requiring reproducible retention time precision (<0.1% RSD) and peak area repeatability (<1.0% RSD).
  • Environmental analysis of pesticides, PAHs, and pharmaceutical residues in water and soil extracts.
  • Food safety testing for mycotoxins, preservatives, and synthetic dyes using validated AOAC or EN methods.

FAQ

What does “Agilent Certified Refurbished” mean?

It signifies that the instrument has been inspected, repaired, recalibrated, and performance-verified by Agilent’s own engineers using original components and factory test procedures—meeting the same functional and reliability criteria applied to new 1100 Series systems.
Is the refurbished 1100 compatible with modern Agilent software and accessories?

Yes. Firmware is updated to the latest supported revision, and hardware interfaces remain fully compatible with current ChemStation releases and all Agilent-branded columns, guard cartridges, and system modules designed for the 1100/1200 platform.
Does the one-year warranty cover on-site service?

Warranty includes parts, labor, and travel for on-site repair where covered under Agilent’s regional service coverage map; response times follow standard SLAs defined in the service agreement.
Can this system be upgraded to support advanced detection or automation?

Yes. The 1100 chassis supports modular expansion including diode array detection (G1315B), fluorescence detection (G1321A), and integration with Agilent’s 600-series fraction collectors or robotic sample handling systems—subject to interface compatibility and power requirements.
Are IQ/OQ documents provided with the instrument?

Each unit ships with a Certificate of Refurbishment and a completed Factory OQ report; site-specific IQ documentation templates and execution support are available through Agilent Professional Services upon request.

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