ANYAN Integrated Nitrogen Generator Series – Membrane-Based On-Site N₂ Supply System
| Brand | ANYAN |
|---|---|
| Origin | Zhejiang, China |
| Manufacturer Type | Authorized Distributor |
| Instrument Type | On-Site Nitrogen Generator |
| Nitrogen Generation Principle | Polymeric Membrane Separation |
| Output Flow Rate | 1–60 L/min (model-dependent) |
| Output Pressure | 0–0.6 MPa |
| Nitrogen Purity | 99.0%–99.999% (v/v) |
| Dew Point | −45 °C |
| Filtration Stages | Triple-Stage (particulate < 0.01 µm |
| Compressor Integrated | Yes (acoustically suspended) |
| Power Supply | 220 V / 50 Hz or 380 V / 50 Hz |
| Total Power Consumption | 450–3800 W (model-dependent) |
| Dimensions (L×W×H) | 500×330×710 mm to 400×300×1300 mm |
Overview
The ANYAN Integrated Nitrogen Generator Series is an on-site, membrane-based nitrogen supply system engineered for continuous, reliable operation in analytical laboratories, QC/QA environments, and industrial process support applications. Unlike cryogenic air separation or pressure swing adsorption (PSA) systems, this generator employs asymmetric polymeric hollow-fiber membranes—optimized for selective permeation of oxygen, CO₂, water vapor, and other fast-permeating gases—leaving nitrogen and inert components enriched on the retentate side. The process requires no consumables beyond compressed air feed, operates without chemical regeneration cycles, and delivers stable output across variable demand profiles. All models integrate a high-efficiency, low-noise scroll compressor with vibration-dampened mounting and acoustic enclosure—eliminating the need for external air compressors and minimizing facility integration complexity. The system is designed for ambient air intake within controlled laboratory environments, with inlet filtration preventing particulate and hydrocarbon contamination that could compromise membrane integrity or downstream instrument performance.
Key Features
- Integrated air compression system with acoustic suspension design—reduces operational noise to ≤55 dB(A) at 1 m distance
- Triple-stage pre-filtration: coalescing filter (0.01 µm), activated carbon adsorber (hydrocarbon removal), and desiccant dryer—ensuring inlet air quality compliant with ISO 8573-1 Class 2:2:2
- High-selectivity polymeric membrane modules with Korean-sourced CMS-compatible support layers—optimized for long-term stability under continuous load
- Dual independent pressure regulation: upstream (feed air) and downstream (N₂ delivery)—enabling precise control over purity/flow trade-offs
- Real-time digital purity display (electrochemical O₂ sensor-based, range 0–1000 ppm O₂ equivalent) with ±0.1% accuracy and automatic temperature/pressure compensation
- Onboard dew point monitoring (−45 °C typical) verified per ISO 8573-3:2010 methodology using chilled-mirror hygrometry
- Modular chassis architecture supporting field-upgradable flow capacity (1–60 L/min) via standardized membrane cartridge replacement
Sample Compatibility & Compliance
This nitrogen generator is compatible with gas chromatography (GC), liquid chromatography–mass spectrometry (LC-MS), elemental analyzers, glove boxes, and inert atmosphere reactors requiring ≥99.0% N₂ purity. It meets critical operational requirements for regulated environments: airflow stability complies with ASTM D6352–20 (standard test method for gaseous nitrogen purity verification); electrical safety conforms to IEC 61010-1:2010; and electromagnetic compatibility satisfies EN 61326-1:2013 (industrial environment class). While not certified to FDA 21 CFR Part 11 out-of-the-box, the system supports audit-ready data logging when paired with validated third-party software enabling electronic signature, user access control, and change history tracking—facilitating GLP/GMP alignment in pharmaceutical and clinical labs.
Software & Data Management
The generator includes embedded firmware with RS-485 Modbus RTU interface for integration into centralized lab infrastructure management platforms (e.g., LabVantage, Thermo Fisher SampleManager). Real-time parameters—including outlet pressure, flow rate, O₂ residual, dew point, compressor runtime, and filter service intervals—are logged locally with 30-day circular memory. Optional Ethernet/Wi-Fi gateway enables remote monitoring via web dashboard or SNMP traps. All logged events include UTC timestamping and are exportable as CSV files compliant with ISO/IEC 17025 documentation traceability standards. No proprietary cloud dependency: raw data remains fully accessible and exportable without vendor lock-in.
Applications
- Carrier and purge gas for GC-FID, GC-TCD, and GC-ECD systems—eliminating cylinder logistics and ensuring consistent baseline stability
- Collision/reaction gas for triple-quadrupole and Q-TOF mass spectrometers in LC-MS/MS workflows
- Inert blanketing during sample preparation, solvent evaporation, and reagent storage
- Zero-air generation support (when coupled with catalytic oxidation units) for ambient air monitoring calibrations
- Process gas for plasma etching, sputtering, and thin-film deposition R&D setups requiring moderate-purity N₂
FAQ
What is the recommended inlet air quality for optimal membrane life?
Ambient air must be filtered to ISO 8573-1 Class 2:2:2 (≤0.1 µm particles, ≤0.1 mg/m³ oil aerosol, ≤0.1 ppm oil vapor) prior to entering the generator. Laboratory air containing volatile organic compounds (e.g., from GC septum bleed or HPLC mobile phase evaporation) should be avoided; dedicated outdoor air intake or ducted cleanroom air is advised.
Can this generator supply nitrogen for ECD detectors?
Yes—provided the integrated triple-stage filtration and optional post-generator deoxygenation tube (e.g., copper catalyst at 350 °C) are used to reduce residual O₂ to <1 ppm and moisture to <−70 °C dew point, meeting ASTM D6352–20 specifications for electron capture detection.
Is the system suitable for LC-MS applications requiring >30 L/min flow?
The AYAN-60L model delivers up to 60 L/min at 99.5% purity; however, for high-flow LC-MS applications demanding >99.999% N₂ (e.g., high-resolution Orbitrap systems), supplemental purification (e.g., PSA polishing stage) or hybrid liquid nitrogen backup remains advisable per manufacturer recommendations.
How often do the filters and membranes require replacement?
Pre-filters are rated for 6,000 hours of operation under ISO-compliant inlet air; membrane modules maintain ≥95% initial performance for ≥15,000 hours when operated within specified pressure/temperature limits. Replacement intervals are tracked automatically and signaled via front-panel alert.
Does the generator comply with electrical safety standards for laboratory use?
Yes—it is constructed and tested per IEC 61010-1:2010 for measurement, control, and laboratory equipment, including protection against electric shock, mechanical hazards, and abnormal heat generation under continuous duty.






