IKA EasySyn 2000 Starter Benchtop Glass Reactor System

Overview

The IKA EasySyn 2000 Starter is a fully integrated, benchtop-scale glass reactor system engineered for reproducible and scalable chemical synthesis under controlled temperature, pressure, and agitation conditions. Designed around Couette-type mixing dynamics and vacuum-compatible sealed architecture, it supports both organic and aqueous reaction pathways—from exploratory lab-scale screening to pilot-stage process development. Its core configuration centers on a 2 L double-jacketed borosilicate glass 3.3 vessel (DIN 28735 compliant), enabling precise thermal management via external circulation baths while maintaining full optical access and chemical inertness. The system operates across an extended thermal envelope of –50 °C to +200 °C and achieves ultimate vacuum levels down to 3 mbar—sufficient for solvent removal, reduced-pressure distillations, moisture-sensitive reactions, and inert-atmosphere purging protocols. As a modular platform, the EasySyn 2000 Starter conforms to fundamental engineering principles of laboratory-scale process intensification: geometric scalability, mass/heat transfer optimization, and operator ergonomics.

Key Features

• DN 150 standardized flange interface with FEP-coated O-ring sealing, ensuring long-term chemical resistance against strong acids, bases, and halogenated solvents
• Ergonomic height-adjustable support frame (500 × 950 × 580 mm), accommodating diverse user anthropometrics and facilitating safe vessel loading/unloading
• Spring-loaded PTFE-lined bottom discharge valve designed to prevent mechanical stress-induced glass fracture during repeated actuation
• EUROSTAR 60 digital overhead stirrer delivering up to 60 N·cm torque with brushless motor control, integrated speed feedback, and programmable ramp profiles
• Vacuum-rated mechanical shaft seal rated for continuous operation at ≤3 mbar, eliminating lubricant contamination and supporting GLP-compliant documentation
• Multi-port reactor head with four standardized ground-glass joints (1 × NS 29/32 center port, 2 × NS 29/32 side ports, 1 × NS 14/23 auxiliary port) for flexible integration of condensers, thermometers, addition funnels, or gas inlets
• PTFE-coated helical impeller optimized for high-shear mixing in low-to-medium viscosity media, minimizing dead zones and improving reagent homogeneity

Sample Compatibility & Compliance

The EasySyn 2000 Starter is compatible with a broad spectrum of chemically aggressive reagents—including concentrated mineral acids (e.g., H₂SO₄, HNO₃), alkalis (e.g., NaOH, KOH), anhydrous solvents (THF, DMF, acetonitrile), and organometallic precursors—due to its all-glass wetted path and fluoropolymer sealing components. All glassware meets DIN ISO 3585 specifications for borosilicate glass 3.3, guaranteeing hydrolytic class HC1 resistance and thermal shock tolerance ≥100 K. The system supports compliance with ASTM E2500-13 (good practice in equipment qualification), ISO/IEC 17025:2017 (for method validation in contract labs), and FDA 21 CFR Part 11 when paired with IKA LabWorld software and audit-trail-enabled controllers. It is routinely deployed in environments requiring GMP-aligned documentation, such as API intermediate synthesis and polymerization R&D.

Software & Data Management

While the EasySyn 2000 Starter base configuration operates via standalone analog/digital controls, it is natively compatible with IKA LabWorld software suite for centralized parameter logging, remote supervision, and automated sequence execution. LabWorld enables time-stamped recording of stirring speed, jacket temperature setpoints, vacuum level (when interfaced with optional digital vacuum gauge), and external probe inputs (e.g., Pt100, RTD). All data exports in CSV or PDF format with configurable metadata fields—including operator ID, batch number, and timestamped event markers—support traceability requirements under GLP and internal QA procedures. Optional integration with IKA RTC series temperature controllers and Vacuubrand vacuum pumps allows closed-loop PID regulation and fault-condition alerting via email/SNMP.

Applications

• Batch-wise synthesis of fine chemicals and pharmaceutical intermediates under reflux, nitrogen blanket, or vacuum
• Kinetic studies requiring precise temperature ramping and real-time agitation control
• Grignard, lithiation, and hydride reductions where exclusion of atmospheric moisture/oxygen is critical
• Polycondensation and step-growth polymerizations monitored by viscosity or endpoint titration
• Crystallization screening across variable supersaturation profiles and seeding protocols
• Extraction and phase-transfer catalysis with simultaneous heating, stirring, and inert gas sparging

FAQ

Is the EasySyn 2000 Starter suitable for exothermic reactions requiring rapid cooling?
Yes—the double-jacketed 2 L vessel enables efficient heat exchange with circulating coolant (e.g., ethanol/water mixtures or silicone oil), supporting cooling rates up to 3 K/min depending on bath temperature differential and flow rate.
Can the system be upgraded to include automated dosing or pH monitoring?
Yes—via optional IKA Dosing Pump modules (e.g., DosiPump 2000) and pH/Redox electrode interfaces compatible with the LabWorld platform.
What maintenance is required for the vacuum seal and stirring mechanism?
The FEP O-ring should be inspected for compression set every 6 months; the mechanical stirrer shaft seal requires no routine lubrication and is rated for >10,000 hours of continuous vacuum operation.
Does the system meet electrical safety standards for international laboratories?
Yes—it complies with IEC 61010-1:2010, EN 61326-1:2013 (EMC), and carries CE, UKCA, and cULus marks for use in North America, EU, and APAC regions.
Are replacement vessels and custom port configurations available?
Yes—IKA offers alternative vessel volumes (500 mL, 1 L, 3 L), variants with side ports or sight glasses, and bespoke lid assemblies with additional NS or QuickFit interfaces.