LeadFluid TYD01-01 (V3) Benchtop Syringe Pump

Overview

The LeadFluid TYD01-01 (V3) is a precision-engineered benchtop syringe pump designed for demanding laboratory applications requiring accurate, repeatable, and programmable fluid delivery at micro- to milliliter-scale flow rates. Based on linear stepper motor-driven lead screw actuation, the pump converts rotational motion into precise axial displacement of the syringe plunger—enabling volumetric control governed by syringe geometry, step resolution, and motor timing. Its architecture adheres to fundamental principles of positive displacement pumping, where flow rate is determined by plunger velocity and cross-sectional area of the syringe barrel. This deterministic relationship ensures high reproducibility across extended operation cycles, making the TYD01-01 (V3) suitable for applications including microfluidics, analytical sample introduction, electrophysiology perfusion, chromatography mobile phase delivery, and controlled reagent dosing in reaction kinetics studies.

Key Features

• 5-inch high-resolution color LCD touchscreen with intuitive graphical interface, supporting multi-point capacitive touch and responsive menu navigation
• Single-syringe mounting configuration compatible with standard plastic or glass syringes ranging from 10 µL to 60 mL capacity
• High-strength aerospace-grade ball bearings replace conventional bronze bushings in the lead screw assembly—reducing mechanical hysteresis, extending service life, and maintaining long-term positional fidelity
• Robust electromagnetic interference (EMI) shielding enabling stable operation in environments with high-voltage electrostatic fields (e.g., near electrospray ionization sources or plasma generators)
• Five programmable operating modes: Infuse Only, Withdraw Only, Infuse/Withdraw, Continuous Infuse, and Continuous Withdraw—each configurable with ramp profiles, pause intervals, and cycle counts
• Integrated hardware-level safety features including syringe stall detection, occlusion pressure monitoring (via motor current signature analysis), and automatic stop on error condition
• Front-panel key lock and silent-key mode to prevent unintended parameter changes during unattended runs

Sample Compatibility & Compliance

The TYD01-01 (V3) supports all Luer-lock and Luer-slip syringes conforming to ISO 8536-4 and ISO 594 standards. It accommodates both disposable polypropylene syringes and borosilicate glass syringes with metal or PTFE-tipped plungers. While not certified for use in GMP manufacturing environments, the device meets CE marking requirements for laboratory equipment (2014/30/EU EMC Directive and 2014/35/EU LVD Directive). Its Modbus RTU implementation over RS-485 enables integration into systems compliant with FDA 21 CFR Part 11 when paired with validated host software that enforces electronic signatures, audit trails, and role-based access control.

Software & Data Management

The pump communicates via isolated RS-485 serial interface using industry-standard Modbus RTU protocol (function codes 03h, 06h, 10h), allowing seamless integration with PLCs, DAQ systems, custom LabVIEW or Python-based controllers, and SCADA platforms. Firmware supports up to 10 user-defined protocols stored internally—each containing complete parameter sets (target volume, flow rate, acceleration, dwell time, mode selection). All executed protocols are timestamped and logged in non-volatile memory. Optional PC software provides real-time flow visualization, batch export of operation logs (.csv), and firmware update capability. Audit trail functionality—including operator ID, parameter change history, and execution timestamps—is available when used with compliant third-party supervisory software.

Applications

• Controlled delivery of nanoliter-volume reagents in single-cell injection and CRISPR-Cas9 transfection workflows
• Steady infusion of calibration standards in ICP-MS and HPLC-ICP-MS hyphenated systems
• Perfusion of neuronal cultures in patch-clamp electrophysiology rigs with sub-microliter temporal resolution
• Sequential reagent addition in automated kinetic assays for enzyme characterization (e.g., Michaelis-Menten analysis)
• Delivery of viscous polymer solutions or nanoparticle suspensions in microfabrication and soft lithography setups
• Integration into custom-built chemical synthesis reactors requiring precise stoichiometric feeding under inert atmosphere

FAQ

What syringe sizes are supported?
Syringes from 10 µL to 60 mL capacity are fully supported, including common brands such as BD, Hamilton, and SGE. Custom syringe geometry can be defined manually using inner diameter and maximum stroke length.
Does the pump support bidirectional flow control?
Yes—the Infuse/Withdraw mode allows alternating direction within a single program, with independent flow rate and volume settings for each phase.
Is external triggering supported?
Yes—TTL-compatible digital inputs accept start/stop and direction signals, enabling synchronization with external events such as camera acquisition or laser pulses.
Can multiple pumps be daisy-chained via RS-485?
Yes—up to 32 units can share a single RS-485 bus using unique Modbus slave IDs; no additional hub or repeater is required.
What power input specifications does the unit require?
Universal AC input: 100–240 VAC, 50/60 Hz, with internal switching power supply delivering regulated DC to motor and logic circuits.