Shimadzu LC-2030 Plus Integrated HPLC System (Refurbished)
| Brand | Shimadzu |
|---|---|
| Origin | Japan |
| Model | LC-2030 Plus |
| Flow Rate Range | 0.0001–10 mL/min |
| Maximum Pressure | 44 MPa |
| Autosampler Capacity | 216 positions (1.5 mL vials) |
| Injection Volume Range | 0.1–100 µL |
| Column Oven Temperature Range | (Ambient −10) to 85 °C |
| UV-Vis Detection Wavelength Range | 190–700 nm |
| Data Acquisition Rate | 100 Hz |
| Warranty | 1 year |
Overview
The Shimadzu LC-2030 Plus Integrated HPLC System (Refurbished) is a fully integrated, benchtop high-performance liquid chromatography platform engineered for precision, reliability, and operational efficiency in regulated and research laboratory environments. Designed and manufactured in Japan, the LC-2030 Plus employs a modular yet compact architecture that integrates pump, autosampler, column oven, and photodiode array (PDA) or UV-Vis detector into a single, space-optimized unit—eliminating inter-unit tubing delays and minimizing system dwell volume. Its core measurement principle relies on gradient or isocratic elution coupled with real-time UV-Vis absorbance detection across 190–700 nm, enabling quantitative and qualitative analysis of small-molecule pharmaceuticals, natural products, polymers, environmental contaminants, and food additives. The system supports both reversed-phase and normal-phase separations, with robust pressure tolerance up to 44 MPa (6380 psi), facilitating use with sub-2-µm particle columns for high-resolution UHPLC-grade separations without requiring external high-pressure hardware.
Key Features
- Integrated design reduces system volume and gradient delay, improving retention time reproducibility and method transfer fidelity.
- Ultra-low flow precision: 0.0001 mL/min minimum step resolution supports nano- and micro-flow applications with high accuracy and pulse-free delivery.
- 216-position autosampler with 1.5 mL vial capacity and programmable injection volumes from 0.1 to 100 µL—enabling unattended batch analysis with low carryover (<0.005%) and temperature-controlled sample tray (4–40 °C optional).
- Column oven with precise thermal control from (ambient −10) to 85 °C ensures retention time stability across ambient fluctuations and supports method robustness validation per ICH Q5A and Q2(R2).
- UV-Vis detector featuring 100 Hz data acquisition rate and spectral bandwidth ≤1.2 nm delivers high-fidelity peak shape capture and baseline stability—critical for co-elution resolution and peak purity assessment.
- Refurbishment protocol includes full mechanical inspection, pump seal replacement, detector lamp calibration, autosampler syringe cleaning and verification, and firmware update to latest stable release (LCsolution Lite v2.0 or later).
Sample Compatibility & Compliance
The LC-2030 Plus accommodates standard 4.6 mm × 150 mm analytical columns as well as narrow-bore (2.1 mm ID) and capillary formats. It is compatible with aqueous, organic, and mixed mobile phases including acetonitrile, methanol, water, buffers (e.g., ammonium formate, phosphate), and ion-pairing reagents. All fluidic pathways are constructed from inert stainless steel and PEEK—ensuring compatibility with pH 1.5–10.5 mobile phases and minimizing metal-catalyzed degradation. The system meets essential requirements for GLP and GMP environments: audit trail functionality (via LCsolution Lite software), electronic signature support (21 CFR Part 11 compliant configuration available upon request), and traceable calibration records. It aligns with ASTM D7097 (hydrocarbon analysis), USP (chromatography), and ISO/IEC 17025:2017 method validation frameworks.
Software & Data Management
Controlled via Shimadzu’s LCsolution Lite software (Windows 10/11 compatible), the LC-2030 Plus provides intuitive instrument setup, sequence definition, real-time monitoring, and post-run processing—including peak integration, library search (NIST-compatible), purity angle calculation, and custom report generation. Raw data is stored in proprietary .lcd format with embedded metadata (instrument ID, operator, timestamp, method parameters). Export options include CSV, PDF, and AIA/ANDI-compliant formats for LIMS integration. Data integrity safeguards include automatic backup, user-level access control (administrator/operator/visitor roles), and tamper-evident file hashing. Optional upgrade to LabSolutions IR allows multi-instrument network management and centralized archive server deployment.
Applications
- Pharmaceutical QC: Assay, related substances, and dissolution testing per USP monographs.
- Biopharmaceutical characterization: Peptide mapping, residual solvent analysis, and excipient quantification.
- Environmental labs: PAHs, PCBs, pesticides, and endocrine disruptors in water and soil extracts.
- Food & beverage: Preservatives (sorbic/benzoic acid), sweeteners (aspartame, sucralose), mycotoxins (aflatoxin B1), and vitamin profiling.
- Academic research: Natural product isolation tracking, reaction monitoring, and polymer molecular weight distribution (GPC mode with appropriate columns).
FAQ
Is this unit factory-refurbished or third-party refurbished?
This LC-2030 Plus system undergoes a certified refurbishment process performed by Shimadzu-authorized service technicians in accordance with OEM technical bulletins—covering full functional testing, optical alignment, pressure leak verification, and chromatographic performance qualification using caffeine/uracil test mixtures.
What documentation accompanies the system?
Each unit ships with a Certificate of Refurbishment, detailed service log, calibration report (pump flow accuracy, detector linearity, wavelength accuracy), and one-year limited warranty covering parts and labor.
Can the system be validated for GMP use?
Yes—IQ/OQ documentation templates are provided, and PQ protocols can be developed in collaboration with the buyer’s QA team. Full 21 CFR Part 11 compliance requires optional software licensing and network configuration.
Are spare parts and consumables readily available?
All critical spares—including pump seals, autosampler rotors, flow cells, and deuterium/tungsten lamps—are stocked globally through Shimadzu’s distribution network and supported by 72-hour air freight logistics.
Does the system support method transfer from older Shimadzu platforms?
Yes—LCsolution Lite maintains backward compatibility with methods created on LC-2010HT, LC-20AT, and Prominence systems; retention time shifts are typically <0.2% RSD when using identical column and mobile phase conditions.
