Thermo Scientific Versa CART Mobile Accessories Cart
| Brand | Thermo Scientific |
|---|---|
| Origin | USA |
| Manufacturer Type | Manufacturer |
| Origin Category | Imported |
| Model | Versa CART |
| Pricing | Upon Request |
Overview
The Thermo Scientific Versa CART Mobile Accessories Cart is an engineered platform designed to support modular, GMP-compliant liquid handling workflows in biopharmaceutical manufacturing environments. Built on a rigid stainless-steel frame with cleanroom-compatible finishes, the Versa CART serves as a mobile integration hub for single-use systems—enabling rapid reconfiguration across upstream and downstream unit operations without compromising sterility assurance or spatial efficiency. Its core function is not measurement or processing, but intelligent physical orchestration: it provides standardized mechanical interfaces, power/data routing pathways, and ergonomic access points for pumps, flow sensors, pressure transducers, load cells, and single-use bags or filters. The cart operates within the broader context of process intensification strategies—supporting flexible facility design, reduced changeover time, and enhanced traceability through structured hardware deployment.
Key Features
- Modular architecture with standardized mounting rails and DIN-rail compatible brackets for plug-and-play integration of peristaltic pumps, digital flow meters, and analog/digital I/O modules.
- Height-adjustable rotating tray system with 360° swivel capability and lockable positioning—designed to accommodate varying bag port heights and operator reach requirements (adjustable range: 75–120 cm above floor level).
- Side-mounted adjustable filter supports with dual-axis tilt and vertical translation—compatible with standard 0.22 µm and 0.45 µm PES, PVDF, and nylon membrane cassettes used in normal-flow and tangential-flow filtration (TFF) applications.
- Integrated load cell system with ±0.1% full-scale accuracy (calibrated per ASTM E4), enabling real-time mass-based volume calculation for single-use bioprocess bags (e.g., 5–200 L capacity), traceable to NIST standards.
- Cleanroom-optimized footprint (W × D × H: 610 × 762 × 1524 mm) with non-marking, static-dissipative casters (two fixed, two swivel with total-lock brakes) compliant with ISO Class 5–7 environmental controls.
- Pre-wired conduit pathways for 24 VDC instrumentation power and shielded RS-485/Modbus RTU communication—facilitating seamless connection to supervisory control systems and SCADA networks.
Sample Compatibility & Compliance
The Versa CART is validated for use with industry-standard single-use components including Sartorius, Pall, and Thermo Fisher single-use bioreactors, mixing bags, and filtration cassettes. It supports operation under current Good Manufacturing Practice (cGMP) conditions per 21 CFR Parts 210/211 and EU Annex 1 requirements for sterile manufacturing. All structural materials meet USP Class VI biocompatibility testing criteria. The cart’s mechanical design allows for routine cleaning validation using approved sanitants (e.g., 70% IPA, Virox®), and its surface finish (Ra ≤ 0.8 µm electropolished 316L stainless steel) complies with ASME BPE-2022 surface roughness specifications for pharmaceutical equipment.
Software & Data Management
While the Versa CART itself contains no embedded firmware or standalone software, its hardware interface design enables native integration into validated process control ecosystems. Load cell outputs are compatible with Thermo Fisher’s VIAFLO Connect™ and other third-party SCADA platforms (e.g., Siemens Desigo CC, Rockwell FactoryTalk) via Modbus TCP or analog 4–20 mA signals. Audit trail functionality—including timestamped weight readings, operator ID, and cart configuration metadata—is maintained at the supervisory system level in accordance with FDA 21 CFR Part 11 and EU Annex 11 data integrity requirements. Configuration changes are documented in electronic batch records (EBRs) aligned with GAMP 5 risk-based validation protocols.
Applications
- cGMP commercial and clinical-scale biologics manufacturing—including monoclonal antibodies, recombinant proteins, viral vectors, and mRNA-LNPs.
- Upstream processing: media and buffer preparation, seed train expansion, inoculum transfer, harvest collection, and perfusion feed control.
- Downstream processing: buffer exchange, clarification, chromatography column packing and elution support, ultrafiltration/diafiltration (UF/DF), and final formulation fill prep.
- Process development labs requiring rapid re-deployment between benchtop and pilot-scale configurations while maintaining consistent human factors and utility interface standards.
FAQ
Is the Versa CART certified for use in ISO Class 5 cleanrooms?
Yes—the cart’s materials, surface finish, and caster selection comply with ISO 14644-1 requirements for airborne particulate cleanliness; however, final classification depends on facility-specific HVAC performance and operational protocols.
Can the Versa CART be integrated with automated liquid handling robots?
It is not a robotic platform, but its standardized mounting interfaces and signal compatibility enable coordinated operation with robotic arms (e.g., Hamilton STAR, Tecan Fluent) for semi-automated bag docking and sensor actuation.
Does Thermo Scientific provide IQ/OQ documentation for the Versa CART?
Yes—factory-issued Installation Qualification (IQ) and Operational Qualification (OQ) protocols are available upon request, aligned with ASTM E2500 and ISPE Baseline Guide principles.
What is the maximum load capacity of the rotating tray?
The tray supports up to 45 kg distributed load when fully extended; dynamic stability is maintained at all height settings per ANSI/UL 969 labeling and structural safety standards.
Are replacement parts and service kits available globally?
Yes—Thermo Fisher maintains regional spare parts distribution centers in North America, EMEA, and APAC, with lead times typically under 5 business days for standard components.
