Sievers 900 Laboratory Total Organic Carbon (TOC) Analyzer
| Origin | Canada |
|---|---|
| Manufacturer Type | Authorized Distributor |
| Origin Category | Imported Instrument |
| Model | Sievers 900 |
| Price Range | USD 13,500 – 40,500 (FOB) |
| Product Category | TOC Analyzers |
| Operational Age | 3–4 Years |
| Warranty | 12 Months |
Overview
The Sievers 900 Laboratory Total Organic Carbon (TOC) Analyzer is a validated, oxidation-based analytical system engineered for precise quantification of non-purgeable organic carbon (NPOC) and total carbon (TC) in aqueous samples. Utilizing high-temperature catalytic combustion (680 °C) with platinum-catalyzed oxidation and selective CO₂ detection via solid-state, non-dispersive infrared (NDIR) sensing, the instrument delivers trace-level TOC measurement across a dynamic range of 1 ppb to 50,000 ppb (as C), with sub-ppb detection capability under optimized conditions. Designed for regulated laboratory environments—including pharmaceutical QC labs, biotechnology process development, and environmental monitoring facilities—the Sievers 900 complies with core method validation requirements outlined in USP , EP 2.2.44, ASTM D7573, and ISO 8245. Its architecture supports GLP/GMP workflows through built-in audit trail functionality, electronic signature readiness, and full compliance with FDA 21 CFR Part 11 when deployed with validated software configurations.
Key Features
- Automated calibration and system suitability verification (SSV) using certified sucrose and 1,4-benzoquinone standards—fully programmable per ICH Q2(R2) guidelines
- Integrated reagent management: Onboard acid (phosphoric) and oxidant (sodium persulfate) delivery with real-time flow optimization and auto-dilution for high-concentration samples
- Compact footprint (19.2 cm wide) enabling benchtop deployment in space-constrained cleanrooms or shared analytical laboratories
- Color touchscreen interface with intuitive, icon-driven navigation—supports multi-language UI (English, German, Japanese, Chinese) and customizable method templates
- 12-month calibration stability verified per manufacturer’s performance qualification protocol; reduces frequency of recalibration without compromising data integrity
- Low-maintenance design: No external gas supply required; only two consumables (catalyst tube and NDIR sensor filter) with typical replacement intervals exceeding 12 months under routine use
Sample Compatibility & Compliance
The Sievers 900 accommodates diverse aqueous matrices—including purified water (PW), water for injection (WFI), clean steam condensate, buffer solutions, cell culture media, and environmental surface rinse samples—without manual pretreatment in most cases. Sample introduction is compatible with both syringe injection (for low-throughput verification) and automated sampling via GE Healthcare ASX-120 or equivalent third-party autosamplers supporting random-access vial positioning (up to 120 positions). All hardware and firmware revisions shipped with this unit meet current IEC 61010-1 safety standards and electromagnetic compatibility (EMC) Class B requirements for laboratory instrumentation. Documentation packages include Factory Acceptance Test (FAT) reports, IQ/OQ protocols, and full traceability to NIST-traceable reference materials.
Software & Data Management
Data acquisition and reporting are managed via Sievers Insight™ Software v4.x or higher—validated for use in regulated environments. The platform provides role-based user access control, configurable electronic signatures, and immutable audit trails recording all method changes, calibration events, and result modifications. Raw data files (.sif) are stored in vendor-neutral formats compliant with ALCOA+ principles (Attributable, Legible, Contemporaneous, Original, Accurate + Complete, Consistent, Enduring, Available). Export options include CSV, PDF, and XML for integration into LIMS or ELN systems. Backup and restore functions support daily encrypted local backups and optional network drive synchronization.
Applications
- Pharmaceutical water system monitoring per USP and EU GMP Annex 1
- Bioprocess stream analysis during upstream and downstream purification
- Environmental compliance testing for wastewater discharge permits (EPA Method 415.3)
- Validation of cleaning procedures for multi-product manufacturing equipment
- Research-grade carbon budgeting in aquatic geochemistry and wastewater treatment studies
FAQ
Is this unit supplied with full documentation for regulatory audits?
Yes—each refurbished Sievers 900 includes complete as-shipped documentation: calibration certificates, maintenance logs, software validation summary, and a Certificate of Conformance referencing ASTM E2500-22 for refurbished instrument qualification.
What level of technical support is included post-purchase?
All units include 12 months of remote application support, firmware updates, and priority escalation for critical operational issues. On-site service contracts are available upon request.
Can the instrument be integrated into an existing LIMS environment?
Yes—via standard OPC UA or TCP/IP communication protocols; custom API integrations are supported through documented REST endpoints in Insight™ Software.
Are spare parts and consumables readily available?
All OEM consumables—including catalyst tubes (P/N 7000-1202), NDIR filters (P/N 7000-1203), and reagent kits—are stocked and ship globally within 48 hours.
