ULUPURE UPE Benchtop Ultra-Pure Water System
| Brand | ULUPURE |
|---|---|
| Origin | Sichuan, China |
| Manufacturer Type | Direct Manufacturer |
| Product Category | Domestic |
| Model | UPE |
| Pricing | Upon Request |
| Purified Water Grade | ASTM Type I / ISO 3696 Grade 1 |
| Resistivity | 18.2 MΩ·cm @ 25 °C |
| Heavy Metals & Soluble Silica | ≤0.1 ppb |
| Particles (>0.1 µm) | ≤1 particle/mL |
| Microbial Count | ≤1 CFU/mL |
| RNase | <0.5 pg/mL |
| DNase | <5 pg/mL |
| TOC (with optional dual-wavelength UV) | <10 ppb |
| Endotoxin (with optional 3000 Da UF) | <0.001 EU/mL |
| RO Feed Water Requirement | TDS < 200 ppm, Pressure 0.10–0.40 MPa, Temp 5–45 °C |
| Production Rate | 10 or 20 L/h |
| Flow Rate | 1.0–1.5 L/min |
| Dimensions (W×D×H) | 375 × 505 × 615 mm |
| Weight | ~35 kg |
| Power Supply | AC 220 V, 50 Hz (200–410 W) |
Overview
The ULUPURE UPE Benchtop Ultra-Pure Water System is an integrated, compact laboratory water purification platform engineered for precision applications requiring consistent Type I ultrapure water per ASTM D1193, ISO 3696, CLSI, USP, EP, and GB/T standards. It employs a multi-stage purification architecture combining dual-stage reverse osmosis (RO), continuous electrodeionization (EDI), ultraviolet photo-oxidation (254 nm and optional 185/254 nm), 0.2 µm terminal microfiltration, and proprietary double-layer medical-grade polyethylene (PE) storage with sterile venting. Unlike conventional single-pass systems, the UPE integrates intelligent recirculation with real-time conductivity and resistivity monitoring at four critical points—RO permeate, RO dispensing port, EDI output, and final UP outlet—ensuring trace-level contaminant control across the entire distribution loop. Its design prioritizes operational reliability in regulated environments, supporting GLP-compliant workflows through audit-ready data logging and configurable alarm thresholds.
Key Features
- Four-point real-time water quality monitoring: RO feed, RO product, EDI effluent, and final UP outlet—each with independent conductivity/resistivity sensors calibrated to NIST-traceable standards.
- Intelligent multi-path recirculation loop with automatic超标 discharge (excess conductivity purge), minimizing microbial regrowth and maintaining end-point stability within ±0.1 MΩ·cm over extended operation.
- ULUPURE patented double-layer sterile PE water tank (ZL201610787560.5), equipped with hydrophobic 0.2 µm vent filter and integrated dispensing faucet—designed to prevent airborne contamination during storage and retrieval.
- 4.3-inch capacitive touchscreen interface with intuitive icon-driven navigation, multilingual support (English, Chinese, Spanish), and password-protected administrator mode for parameter lockout.
- USB-based data export functionality: stores timestamped records of volume dispensed, resistivity trends, system alarms, maintenance alerts, and cartridge usage history—compatible with CSV import into LIMS or QA documentation systems.
- Modular consumables architecture: RO membranes, EDI stacks, UV lamps, and MF cartridges are field-replaceable without tools; service intervals calculated dynamically based on feed water TDS and cumulative throughput.
Sample Compatibility & Compliance
The UPE system delivers water meeting or exceeding specifications for critical analytical and life science applications including HPLC, LC-MS, ICP-MS, AAS, IC, PCR, qRT-PCR, cell culture (including stem and primary cells), IVF, electrophoresis, and monoclonal antibody purification. Its final water output complies with ISO 3696:1995 Class 1, ASTM D1193-20 Type I, USP Purified Water and Water for Injection (WFI) criteria when paired with optional 3000 Da ultrafiltration and dual-wavelength UV. The system supports 21 CFR Part 11 readiness via optional electronic signature modules and audit trail configuration. All wetted materials—including tubing, tanks, and fittings—are USP Class VI-certified and extractables-tested per ISO 10993-12. Full compliance documentation (DQ/IQ/OQ templates, material certificates, calibration reports) is provided upon request.
Software & Data Management
The embedded firmware enables full-cycle water quality traceability. Each dispense event logs volume, time, temperature, resistivity, and user ID (if enabled). Historical data—spanning up to 12 months—is stored internally and exportable via USB flash drive in timestamped, comma-delimited format. Optional Ethernet/Wi-Fi connectivity (add-on module) allows remote status monitoring, predictive maintenance alerts, and integration with enterprise asset management (EAM) platforms. Calibration logs, sensor drift compensation values, and consumable lifetime counters are retained independently and cannot be overwritten—supporting internal audits and regulatory inspections under GLP, GMP, and CAP requirements.
Applications
The UPE system serves as a primary water source for high-sensitivity instrumentation where background interference must be minimized: trace-metal analysis (ICP-MS), low-TOC organic solvent preparation (HPLC mobile phase), nuclease-free molecular biology workflows (CRISPR editing, RNA-seq library prep), endotoxin-sensitive applications (monoclonal antibody formulation, vaccine development), and long-term mammalian cell culture requiring stable osmolality and ion balance. Its modular upgrade path—including 185/254 nm UV, 3000 Da UF, and TOC analyzers—enables adaptation to evolving method requirements without system replacement.
FAQ
What is the minimum feed water quality required for optimal UPE performance?
Feed water must have TDS < 200 ppm, pressure between 0.10–0.40 MPa, and temperature between 5–45 °C. Below 5 °C, RO flux declines significantly; below 0 °C, membrane integrity may be compromised.
Can the UPE meet USP Water for Injection (WFI) specifications?
Out-of-the-box, it meets USP Purified Water standards. With optional 3000 Da ultrafiltration and dual-wavelength UV, endotoxin levels drop to <0.001 EU/mL and TOC to <10 ppb—aligning with WFI purity benchmarks for non-sterile pharmaceutical use.
How often do consumables require replacement?
RO membrane life depends on feed TDS and daily usage; typical interval is 12–24 months. EDI stacks last 3–5 years under standard conditions. UV lamps are rated for 9,000 hours; MF cartridges are replaced every 6–12 months based on particle load.
Is the system compatible with third-party water distribution loops?
Yes—the UP outlet features a standardized 1/4″ compression fitting and pressure-regulated flow control. Integration with external loops requires validation of backpressure, flow dynamics, and microbial control per ISO 22196 and ASTM E2149.
Does the UPE support electronic record retention for FDA audits?
All logged data—including calibration events, alarm history, and user actions—is stored with immutable timestamps and user attribution. Optional 21 CFR Part 11 compliance packages include role-based access control, digital signatures, and encrypted audit trails.
