Savillex PFA Laboratory Ware Set

Overview

Savillex PFA Laboratory Ware represents a benchmark in high-purity, chemically inert sample preparation infrastructure for trace-metal analysis, ultra-trace environmental testing, and regulated pharmaceutical and semiconductor R&D workflows. Constructed from perfluoroalkoxy alkane (PFA), a fully fluorinated thermoplastic polymer, these vessels leverage the molecular stability of carbon–fluorine bonds to deliver exceptional resistance to thermal degradation, mechanical stress cracking, and aggressive chemical attack—including hot concentrated hydrofluoric acid (HF), aqua regia, and boiling nitric, sulfuric, and hydrochloric acids. Unlike glass or standard polypropylene alternatives, PFA exhibits near-zero leachable metal content (typically <10 pg/g for Na, K, Ca, Fe, Cr, Ni, Zn, Cu, and Pb), meeting stringent purity requirements defined in ASTM D4327, ISO 17294-2, and USP . Operating continuously at temperatures from –200 °C to +260 °C, Savillex PFA ware maintains dimensional stability and burst pressure integrity under elevated thermal and vacuum conditions—enabling safe use in hotplate digestion, microwave-assisted acid digestion (MWD), and cleanroom-grade solvent storage.

Key Features

• Ultra-low elemental background: Certified trace-metal-free performance with documented ICP-MS validation reports available upon request
• Thermal resilience: Stable mechanical properties up to 260 °C; compatible with programmable heating blocks, oven drying, and steam sterilization (autoclave-safe at 121 °C/15 psi)
• Stress-crack resistance: Engineered for repeated flexing, sealing, and pressurized cycling—critical for reusable digestion vessels and transfer systems
• Optical clarity & non-wetting surface: Enables visual monitoring of reactions and minimizes sample retention during quantitative transfer
• USP Class VI and FDA-compliant formulation: Meets biocompatibility and food-contact safety standards for regulated applications
• Electrostatic dissipation: Inherently static-dissipative behavior reduces particle adhesion in low-humidity clean environments

Sample Compatibility & Compliance

Savillex PFA laboratory ware is routinely employed in EPA Method 3050B, 3051A, and 3052 digestion protocols; ISO/IEC 17025-accredited environmental labs; and GLP-compliant pharmaceutical stability studies. All items are manufactured in an ISO 9001-certified facility in Minnesota, USA, and undergo batch-specific lot testing for extractables (per USP ) and particulate contamination (per ISO 8573-1 Class 3). Each vessel is individually inspected for wall thickness uniformity, seam integrity, and absence of microfissures using high-resolution digital microscopy. Documentation packages include Certificate of Conformance, Material Safety Data Sheet (MSDS), and optional ISO/IEC 17025-accredited test reports for elemental impurities.

Software & Data Management

While PFA ware itself is passive hardware, Savillex provides integrated digital traceability tools for laboratory asset management. Each product line carries laser-etched alphanumeric lot codes readable by standard barcode scanners, enabling seamless integration with LIMS platforms (e.g., LabWare LIMS, Thermo Fisher SampleManager) and electronic lab notebooks (ELNs) such as Benchling or LabArchives. Optional serialized labeling supports 21 CFR Part 11-compliant audit trails for GMP-regulated environments, including user-defined metadata fields for digestion protocol version, operator ID, and calibration history linkage.

Applications

• Trace-metal analysis (ICP-MS, ICP-OES): Acid digestion of geological, biological, and airborne particulate samples
• High-purity reagent storage: Long-term containment of HF, HNO₃/HF mixtures, and ultra-pure water (UPW) for semiconductor wet processing
• Reference material preparation: Certified reference material (CRM) homogenization and sub-sampling in cleanrooms (ISO Class 5–7)
• Pharmaceutical extractables & leachables (E&L) studies: Simulated extraction under ICH Q5C conditions
• Nanomaterial dispersion and stabilization: Low-surface-energy environment prevents aggregation during sonication and centrifugation
• Radiochemistry: Handling of alpha-emitting isotopes (e.g., Am-241, Pu-239) where minimal background interference is mandatory

FAQ

Are Savillex PFA vessels suitable for microwave-assisted digestion?
Yes—Savillex PFA digestion vessels are validated for use in closed-vessel microwave systems operating up to 300 °C and 100 bar, provided pressure relief mechanisms are in place per manufacturer guidelines.
Can PFA ware be reused after aggressive acid cleaning?
Yes—when cleaned via ASTM D2670-recommended procedures (e.g., sequential rinses with 1% HNO₃, UPW, and acetone), PFA demonstrates >500-cycle durability without measurable elemental leaching or structural fatigue.
Do you provide custom PFA fabrication services?
Savillex offers OEM design consultation and limited-run custom molding for specialized geometries, ports, and fittings—subject to minimum order quantities and NDA execution.
Is PFA compatible with organic solvents like THF or chloroform?
PFA exhibits excellent resistance to most organic solvents at room temperature; however, prolonged exposure to aromatic hydrocarbons (e.g., benzene, toluene) above 100 °C may cause slight swelling and should be avoided.
How does PFA compare to FEP and ETFE in analytical applications?
PFA offers superior thermal stability and lower extractables than FEP; it also provides higher continuous-use temperature and better creep resistance than ETFE—making it the preferred choice for high-temperature digestion and long-duration storage.