DLAB RE100-Pro Rotary Evaporator

Overview

The DLAB RE100-Pro Rotary Evaporator is an engineered solution for efficient, reproducible solvent removal and concentration of heat-sensitive samples under reduced pressure. Based on the fundamental principle of rotary evaporation—where simultaneous rotation, heating, and vacuum application lower the boiling point of solvents while maximizing surface area for vaporization—the RE100-Pro delivers robust performance in synthetic chemistry, natural product isolation, pharmaceutical development, and quality control laboratories. Its 5 L evaporation capacity supports medium-scale batch processing, while the dual-purpose water/oil heating bath enables precise thermal management across a broad operational range (ambient to 180 °C). The system integrates a microprocessor-controlled heating module with ±1 °C temperature stability, ensuring consistent thermal input critical for method transfer and regulatory compliance.

Key Features

• Brushless DC motor drive ensures quiet, maintenance-free operation with stable speed control from 20 to 280 rpm—optimized for both viscous and low-viscosity solutions.
• Electric vertical lift mechanism with 150 mm stroke includes programmable endpoint detection and automatic safety lift: upon power interruption, the motor raises the evaporation flask above the heating bath to prevent thermal shock or glass fracture.
• Patented condenser assembly (Patent No. CN201120513505.X) featuring 1500 cm² effective cooling surface area, designed for high-efficiency vapor condensation and superior solvent recovery rates—even with low-boiling or volatile solvents such as diethyl ether, dichloromethane, or ethyl acetate.
• Double-layer modified PTFE sealing gasket combined with spring-loaded compression ensures leak-tight integrity across wide temperature and vacuum ranges; resistant to corrosion from organic solvents, acids, and bases.
• Detachable control panel with large backlit LCD simultaneously displays real-time values for temperature, rotation speed, and timer—enabling intuitive local operation and flexible benchtop configuration.
• Integrated USB port allows direct connection to a host PC for remote instrument control, automated data logging of temperature and speed profiles, and integration into laboratory information management systems (LIMS).

Sample Compatibility & Compliance

The RE100-Pro accommodates standard ISO/KIMAX-compatible glassware, including 5 L round-bottom flasks, vertical condensers, and vapor-tight receiving flasks. Its design adheres to general safety requirements outlined in IEC 61010-1 for electrical equipment used in laboratory environments. While not certified to specific GMP or GLP hardware standards, the instrument supports compliant workflows through traceable parameter recording (via USB), stable thermal and rotational performance, and repeatable vacuum-assisted evaporation cycles—making it suitable for method development, stability studies, and preparative applications aligned with ASTM E2656 and ISO 17025–recommended practices.

Software & Data Management

No proprietary software is bundled; however, the USB interface provides native CDC/ACM serial communication, enabling interoperability with common scripting environments (e.g., Python via PySerial) or third-party data acquisition platforms. Logged parameters—including setpoints and actual readings for temperature (°C) and rotational speed (rpm)—are timestamped and exportable in CSV format. This facilitates audit-ready documentation, deviation investigation, and alignment with FDA 21 CFR Part 11 principles when deployed within validated computerized systems governed by organizational SOPs.

Applications

• Concentration of crude extracts in phytochemistry and nutraceutical R&D
• Solvent exchange during peptide synthesis and oligonucleotide purification
• Removal of reaction solvents post-catalytic hydrogenation or Grignard coupling
• Preparative-scale isolation of active pharmaceutical ingredients (APIs) prior to crystallization
• High-boiling-point solvent recovery (e.g., DMF, DMSO, NMP) using oil-bath heating up to 180 °C
• Parallel evaporation support when integrated with multi-position manifolds and vacuum controllers

FAQ

What is the maximum recommended vacuum level for routine operation?
The RE100-Pro achieves an ultimate vacuum of 12 mbar; for optimal condensation efficiency and bumping prevention, we recommend operating between 10–50 mbar depending on solvent volatility and bath temperature.
Can the heating bath accommodate both water and silicone oil?
Yes—the 5 L bath is chemically inert and thermally stable for use with water (≤100 °C) or high-temperature silicone oils (up to 180 °C), with automatic overheat protection engaged above 200 °C.
Is the USB interface compatible with Windows, macOS, and Linux?
Yes—the device enumerates as a standard CDC ACM serial device; no drivers are required on modern OS versions (Windows 10+, macOS 12+, recent Linux kernels).
Does the system include vacuum control or require an external pump?
The RE100-Pro does not include vacuum regulation; it requires connection to an external diaphragm or rotary vane pump with appropriate solvent trap and pressure sensor for closed-loop vacuum control.
What glassware accessories are standardized for this model?
It accepts ISO-standard 29/32 and 35/20 ground joints; compatible components include 5 L evaporation flasks, 500 mL receiving flasks, vertical condensers, and vapor-tight adapters—all available separately under DLAB part numbers.