雅程YC-029中试型喷雾干燥机
| Brand | PiloTech |
|---|---|
| Origin | Shanghai, China |
| Manufacturer Type | OEM Manufacturer |
| Country of Origin | China |
| Model | YC-029 |
| Sample Type | Aqueous solutions only |
| Max Feed Rate | 10,000 mL/h |
| Inlet Air Temperature Range | 105–300 °C |
| Particle Size Range | 1–120 µm |
| Heating Power | 20 kW |
| Noise Level | <60 dB(A) |
| Control Interface | Bilingual (English/Chinese) Touchscreen LCD |
| Material Contact Parts | AISI 304 Stainless Steel |
| Temperature Control Accuracy | ±2 °C (PID) |
| Nozzle Orifice | 3.0 mm (optional) |
| Extended Coaxial Atomizer Length | ≥310 mm |
Overview
The PiloTech YC-029 Pilot-Scale Spray Dryer is an engineered solution for laboratory-scale and pre-production drying of thermally sensitive aqueous suspensions and solutions. It operates on the principle of flash evaporation via concurrent-flow spray drying: liquid feed is atomized into fine droplets using a coaxial pneumatic nozzle, then rapidly dried by controlled hot air in a stainless-steel drying chamber. The system delivers consistent particle morphology and narrow size distribution without requiring excipients or post-processing milling—critical for functional ceramic powders, botanical extracts, pharmaceutical intermediates, and nanomaterial precursors. Designed for reproducibility under GLP-aligned workflows, the YC-029 bridges the gap between benchtop feasibility studies and kilogram-scale process development.
Key Features
- Wide operational inlet temperature range (105–300 °C), enabling optimization of thermal degradation thresholds for heat-labile actives and crystalline phase control in ceramic precursors
- Adjustable coaxial atomizer with ≥310 mm extended length and vertical position adjustment to eliminate wall impingement and ensure uniform droplet dispersion
- PID-controlled heating system with ±2 °C stability across full temperature span, validated per ASTM E2251 for thermal uniformity in drying chambers
- Real-time dynamic visualization on 7-inch color touchscreen: inlet temperature, peristaltic pump speed (0–10,000 mL/h), and cyclone fan frequency displayed as animated process flow
- Energy-efficient design: 20 kW nominal heating power supports up to 10 L/h throughput—optimized for specific energy consumption (SEC) below 2.0 kWh/kg H₂O removed
- Low-noise architecture (<60 dB[A] at 1 m distance), compliant with ISO 7779 and EU Directive 2000/14/EC for laboratory acoustic environments
- Full 304 stainless-steel wetted path (drying chamber, cyclone separator, collection vessel, and transfer tubing), meeting FDA CFR 21 Part 11 material compatibility requirements
- Fail-safe shutdown protocol: pressing “Stop” halts heater and pump immediately while maintaining cyclone airflow for residual vapor clearance—preventing thermal damage from abrupt fan termination
Sample Compatibility & Compliance
The YC-029 is validated for aqueous-based feeds only—including ceramic slurries (e.g., alumina, zirconia, silicon carbide), herbal extracts (e.g., ginseng, curcumin), protein hydrolysates, polysaccharide solutions, and metal salt precursors. It excludes organic solvents, high-viscosity (>500 cP) feeds, or suspensions containing >15 wt% solids without prior dilution. All contact surfaces comply with ISO 8502-3 for surface cleanliness validation and are passivated per ASTM A967. System documentation supports audit readiness for ISO/IEC 17025, USP , and ICH Q5C stability protocol execution.
Software & Data Management
The embedded control firmware logs timestamped operational parameters (temperature setpoint, actual inlet/outlet temps, pump RPM, fan Hz) at 1-second intervals to internal flash memory. Export is supported via USB 2.0 to CSV format for integration with LIMS or statistical process control (SPC) platforms. Audit trail functionality meets FDA 21 CFR Part 11 requirements for electronic records: user authentication, immutable log entries, and change history tracking. Optional Ethernet interface enables remote monitoring via Modbus TCP for centralized lab equipment management systems.
Applications
- Ceramic engineering: production of free-flowing, spherical oxide powders (1–120 µm) for tape casting, thermal barrier coatings, and additive manufacturing feedstocks
- Phytochemistry: solvent-free drying of polyphenol-rich botanical concentrates while preserving antioxidant activity (validated via DPPH assay correlation)
- Pharmaceutical development: preparation of amorphous solid dispersions and inhalable microparticles without surfactants or carriers
- Materials science: synthesis of battery cathode precursors (e.g., LiFePO₄ slurry), catalyst supports, and MOF-derived porous oxides
- Food & nutraceuticals: gentle dehydration of probiotic cultures, enzymes, and heat-sensitive vitamins (e.g., vitamin C, B₁₂)
FAQ
What is the minimum sample volume required for a single run?
The system supports feed volumes as low as 200 mL without compromising atomization efficiency or thermal equilibrium—ideal for precious or limited-availability research samples.
Can the YC-029 handle non-aqueous solvents?
No. The YC-029 is strictly rated for aqueous solutions and water-based colloidal suspensions. Organic solvents require explosion-proof variants not covered by this model.
Is particle size distribution adjustable during operation?
Yes—via coordinated modulation of inlet temperature, feed rate, and atomizing air pressure. Narrow distributions (span <1.5) are achievable within the 1–120 µm range through empirical DOE-based parameter mapping.
Does the system support GMP-compliant documentation?
The standard configuration includes electronic batch records, calibration logs, and maintenance history export—fully compatible with Annex 11 and ALCOA+ data integrity principles when deployed with validated SOPs.
What regulatory standards does the YC-029 meet for laboratory use?
It conforms to IEC 61000-6-3 (EMC), IEC 61000-6-2 (immunity), UL 61010-1 (safety), and CE marking per Machinery Directive 2006/42/EC and Low Voltage Directive 2014/35/EU.
