GT-100 Automatic Potentiometric Titrator
| Origin | Japan |
|---|---|
| Manufacturer Type | Authorized Distributor |
| Origin Category | Imported Instrument |
| Model | GT-100 |
| Pricing | Upon Request |
Overview
The GT-100 Automatic Potentiometric Titrator is a fully integrated, benchtop electrochemical titration platform engineered for precision, reproducibility, and regulatory compliance in quality control, pharmaceutical development, and industrial chemical analysis laboratories. Based on potentiometric endpoint detection—measuring the potential difference between a reference and indicator electrode as a function of titrant volume—the GT-100 supports classical volumetric titration principles defined in ISO 8587, ASTM E2081, and USP . Its monolithic architecture combines the control unit, burette drive mechanism, and fluidic manifold into a single compact chassis, minimizing footprint while maximizing mechanical stability and reagent delivery accuracy. Designed for routine and method-critical applications, the system delivers traceable, auditable titration data without external PC dependency, making it suitable for environments operating under GLP, GMP, and ISO/IEC 17025 frameworks.
Key Features
- Integrated hardware design: All core components—including high-precision stepper-driven burettes, microprocessor-based controller, and real-time sensor interface—are housed within a single, space-efficient enclosure.
- Backlit 7-inch LCD display: Presents dynamic titration curves (E vs. V), real-time pH/potential values, delivered volume, status flags, and method progress—optimized for ergonomic viewing under laboratory lighting conditions.
- Multi-mode titration capability: Supports neutralization, redox, precipitation, photometric, conductometric, and polarographic titrations via configurable electrode inputs and algorithm selection.
- Comprehensive method library: Includes fixed-volume titration, endpoint-value detection, preset-potential titration, inflection-point detection (1st/2nd derivative), ASTM D974/D664 oil acidity methods, and start-triggered sequences.
- Expandable fluid handling: Up to 10 motorized burettes or solvent dispensers can be connected—9 for titrants, 1 dedicated for rinsing or conditioning—enabling multi-reagent protocols and automated solvent addition.
- GLP-compliant validation suite: Built-in routines for burette delivery accuracy verification (per ISO 8655-3), electrode calibration logging, system suitability testing, and performance qualification reports.
Sample Compatibility & Compliance
The GT-100 accommodates liquid, semi-solid, and dissolved solid samples across diverse matrices—including pharmaceutical actives, edible oils, petrochemical distillates, wastewater effluents, and food extracts—provided they meet standard electrochemical compatibility criteria (e.g., non-corrosive to Ag/AgCl or glass pH electrodes, minimal suspended solids). When equipped with the optional KF coulometric or volumetric water determination module (KF-100 accessory), the system complies with ASTM E203, ISO 760, and USP for moisture quantification in hygroscopic materials. All firmware operations adhere to FDA 21 CFR Part 11 requirements for electronic records and signatures when paired with validated networked data export workflows.
Software & Data Management
Data acquisition and processing occur onboard via embedded firmware; no external software installation is required for basic operation. Raw titration data—including time-stamped potential/volume pairs, method parameters, operator ID, and environmental metadata—are stored in non-volatile memory supporting up to 100 complete sample records. Each entry retains full traceability: initial electrode calibration values, burette correction factors, and manual or auto-generated pass/fail judgments. Export options include USB-host transfer of CSV-formatted datasets compatible with LIMS integration or statistical review tools (e.g., JMP, Minitab). Audit trails record all parameter modifications, method executions, and calibration events—with immutable timestamps and user authentication logs.
Applications
- Pharmaceutical QC: Assay of active ingredients (e.g., amine hydrochlorides via non-aqueous titration), excipient purity verification, and residual solvent analysis.
- Fuel and lubricant testing: Total acid number (TAN) and total base number (TBN) per ASTM D974, D664, and IP 139.
- Food & beverage: Free fatty acid content in edible oils, chloride in dairy products, and sulfur dioxide in wines.
- Environmental chemistry: Alkalinity and hardness profiling in surface waters, cyanide determination in industrial effluents.
- Materials science: Titration of catalyst precursors, polymer carboxyl content, and metal chelate stoichiometry.
FAQ
Does the GT-100 support remote operation or network connectivity?
The base configuration operates autonomously via its front-panel interface. Optional Ethernet or RS-232 modules enable remote command execution and data streaming under validated IT infrastructure.
Can the GT-100 perform thermometric or amperometric titrations?
No—it is designed exclusively for potentiometric, pH-metric, conductometric, photometric, and polarographic detection modes. Thermometric and amperometric capabilities require dedicated instrumentation.
Is method validation documentation provided with the instrument?
Yes—factory-supplied IQ/OQ protocols, metrological traceability certificates for burette calibration, and GLP-compliance checklists are included in the delivery package.
What electrode types are supported out-of-the-box?
Standard input accepts double-junction pH electrodes, redox (Pt or Ag) electrodes, ion-selective electrodes (e.g., F⁻, Cl⁻), and conductivity cells with analog voltage or current output.
How frequently must the burette delivery accuracy be verified?
Per ISO 8655-3 and internal SOPs, verification is recommended before each analytical batch or at least daily when used in regulated environments.
