Pribolab® LFR-FD Lateral Flow Fluorescence Quantitative Reader
| Brand | Pribolab |
|---|---|
| Origin | Shandong, China |
| Manufacturer Type | Authorized Distributor |
| Regional Classification | Domestic (China) |
| Model | LFR-FD |
| Pricing | Available Upon Request |
Overview
The Pribolab® LFR-FD Lateral Flow Fluorescence Quantitative Reader is an optical benchtop instrument engineered for precise, rapid quantification of analytes captured on lateral flow immunoassay (LFIA) strips labeled with fluorescent nanobeads—typically europium chelate–doped microspheres or quantum dot–conjugated antibodies. Operating on the principle of time-resolved fluorescence (TRF) or steady-state fluorescence detection, the LFR-FD excites labeled test and control lines at defined wavelengths (e.g., 365 nm UV or 470 nm blue LED), captures emitted fluorescence intensity using a high-sensitivity photodiode or CMOS sensor, and converts signal amplitude into concentration values via pre-calibrated standard curves. Designed for routine use in food safety laboratories, veterinary diagnostic centers, environmental monitoring units, and regulatory testing facilities, the system delivers objective, operator-independent results—eliminating subjective visual interpretation while maintaining the speed and simplicity inherent to lateral flow technology.
Key Features
- Optimized optical path with dual-wavelength excitation and narrow-band emission filtering to minimize background interference and enhance signal-to-noise ratio
- Automated strip positioning and scanning alignment ensuring consistent measurement geometry across batches
- Integrated thermal stabilization module to maintain detector sensitivity under ambient temperature fluctuations (15–30 °C operating range)
- Onboard calibration verification using reference strips traceable to internal Pribolab® QC standards
- Touchscreen interface with guided workflow navigation, supporting multilingual UI (English, Spanish, Portuguese, Arabic)
- USB and Ethernet connectivity for data export, remote firmware updates, and integration with LIMS environments
Sample Compatibility & Compliance
The LFR-FD reader is validated exclusively for use with Pribolab®-manufactured lateral flow test cassettes bearing the EQ-LFR 6090 series designation—including assays for mycotoxins (aflatoxin B1, ochratoxin A, fumonisins), veterinary drug residues (tetracyclines, sulfonamides, β-lactams), pathogen antigens (Salmonella, Listeria monocytogenes), and environmental contaminants (microcystin-LR, biotin). All compatible assays are developed and verified per ISO/IEC 17025:2017 requirements for testing laboratories. The instrument supports GLP-compliant operation through configurable user access levels, electronic signature capability, and audit-trail-enabled result logging aligned with FDA 21 CFR Part 11 principles. While not certified as IVD medical devices, selected assay kits meet EU Regulation (EU) 2019/1873 for feed and food contaminant screening.
Software & Data Management
The embedded firmware v3.2.x provides real-time curve fitting using four-parameter logistic (4PL) regression against stored calibration profiles. Raw fluorescence intensities (in arbitrary units), interpolated concentrations (ng/g or µg/kg), and pass/fail status relative to action limits are exported in CSV and PDF formats. Optional Pribolab® LabLink™ desktop software enables centralized database management, cross-instrument trend analysis, and automated report generation compliant with ISO/IEC 17025 documentation requirements. Audit logs record every measurement event—including timestamp, operator ID, strip lot number, calibration status, and environmental sensor readings (ambient temperature/humidity)—retained for ≥12 months unless manually purged.
Applications
- Quantitative screening of aflatoxin M1 in raw milk and dairy products per AOAC Official Method 2019.05
- Multi-residue detection of tetracycline antibiotics in swine liver tissue extracts following EN 14382:2022 extraction protocols
- Field-deployable monitoring of microcystin-LR in surface water samples prior to drinking water treatment
- Batch release testing of animal feed for deoxynivalenol (DON) at levels between 0.1–5.0 mg/kg
- Confirmatory support for ELISA-positive samples in veterinary surveillance programs targeting avian influenza nucleoprotein antigen
FAQ
Is the LFR-FD reader compatible with lateral flow strips from other manufacturers?
No. Optical calibration, strip geometry recognition, and assay-specific algorithms are optimized exclusively for Pribolab® EQ-LFR 6090-series cassettes.
Does the instrument require daily recalibration?
A full calibration check is recommended before each analytical session using the supplied verification strip; no daily recalibration is required if ambient conditions remain stable and the device undergoes weekly performance verification.
Can measurement data be integrated into an existing LIMS?
Yes—via CSV export or optional API-enabled LabLink™ server integration supporting HL7 and ASTM E1384 message formats.
What is the minimum detectable fluorescence signal?
System detection limit is instrument-dependent and defined per assay; typical lower limits of quantification (LLOQ) range from 0.05 to 0.5 ng/mL or equivalent mass-per-strip, as specified in individual kit IFUs.
Is remote technical support available for firmware troubleshooting?
Pribolab® offers secure remote diagnostics via TeamViewer QuickSupport (activated with customer consent) and maintains regional service hubs in Shanghai, Rotterdam, and Chicago for hardware-level intervention.
