PriboLab PriboFast EQ-EVP24 Vacuum Centrifugal Concentrator for Mycotoxin Analysis
| Brand | PriboLab |
|---|---|
| Origin | Shandong, China |
| Manufacturer Type | Authorized Distributor |
| Product Category | Domestic |
| Model | PriboFast EQ-EVP24 |
| Instrument Type | Vacuum Centrifugal Concentrator |
| Capacity | 24-position |
| Heating System | Independent Dry-Block Heater |
| Vacuum Control | Adjustable via External Vacuum Pump |
| Solvent Compatibility | Acetonitrile, Methanol, Chloroform, Ethyl Acetate, and Other Common Extraction Solvents Used in Mycotoxin Analysis |
| Compliance | Designed to Support GLP/GMP-Aligned Mycotoxin Testing Workflows |
Overview
The PriboLab PriboFast EQ-EVP24 Vacuum Centrifugal Concentrator is an engineered solution for rapid, reproducible solvent removal from biological and food safety samples—specifically optimized for multi-mycotoxin workflows including aflatoxin B₁, B₂, G₁, G₂, ochratoxin A, zearalenone, and deoxynivalenol. Operating on the principle of simultaneous centrifugal force, vacuum-assisted evaporation, and precise dry-block heating, the system enables controlled concentration under inert, closed-loop conditions without nitrogen gas. Unlike ambient-air or nitrogen blow-down methods, the EQ-EVP24 maintains sample integrity by minimizing oxidation, thermal degradation, and cross-contamination between adjacent tubes—critical when handling low-concentration mycotoxin extracts prior to HPLC-FLD, LC-MS/MS, or GC-ECD analysis.
Key Features
- 24-position rotor compatible with standard 1.5 mL and 2.0 mL microcentrifuge tubes, as well as 15 mL conical tubes (with optional adapters)
- Independent dry-block heating module with temperature range from ambient +5 °C to 80 °C, adjustable in 1 °C increments—optimized for volatile and thermolabile solvents used in immunoaffinity cleanup (e.g., methanol/water, acetonitrile/water)
- Vacuum interface designed for integration with standard laboratory vacuum pumps (recommended ultimate vacuum ≤ 5 mbar); real-time vacuum level monitoring supported via external gauge
- Centrifugal speed up to 1,800 rpm ensures stable sample retention during active evaporation—preventing bumping, splashing, or tube tipping
- Sealed chamber design eliminates inter-sample vapor migration, fulfilling requirements for parallel processing of multiple regulatory-compliant test batches
- No nitrogen dependency reduces operational cost and eliminates risks associated with high-pressure gas lines, regulator calibration, and inconsistent flow rates
Sample Compatibility & Compliance
The EQ-EVP24 supports all common extraction solvents employed in AOAC Official Method 2005.08, ISO 17372:2018, and GB 5009.22–2016 protocols for aflatoxin analysis. It accommodates samples processed through PriboFast® immunoaffinity columns (e.g., AFB₁-specific, total aflatoxin), as well as extracts derived from QuEChERS-based cleanups. The system’s closed architecture meets fundamental prerequisites for GLP-compliant laboratories conducting routine food and feed testing under CNAS accreditation (ISO/IEC 17025) and aligns with internal SOPs requiring traceability, contamination control, and minimal manual intervention. While the instrument itself does not carry CE or UL certification, its mechanical and thermal specifications conform to IEC 61010-1 safety standards for laboratory equipment.
Software & Data Management
The PriboFast EQ-EVP24 operates via manual front-panel controls—intentionally designed for robustness and ease of validation in regulated environments. No embedded firmware or proprietary software is required, eliminating cybersecurity concerns and simplifying 21 CFR Part 11 compliance when integrated into broader LIMS or ELN ecosystems. Users record operating parameters—including start/end time, set temperature, vacuum duration, and batch ID—in hard-copy or electronic lab notebooks. Optional vacuum pump controllers with analog output (0–10 V) enable logging of real-time vacuum trends using third-party DAQ systems for audit-ready process documentation.
Applications
- Final concentration of aflatoxin eluates post-immunoaffinity purification prior to HPLC-FLD quantification
- Pre-concentration of LC-MS/MS extracts to enhance signal-to-noise ratio and lower method detection limits (MDLs)
- Parallel processing of cereal, nut, spice, and dairy samples in high-throughput food safety screening labs
- Downstream preparation of reference material dilutions and calibration standards in certified reference laboratories
- Integration with PriboFast® KRC/MFU photochemical derivatization systems where solvent residue must be minimized before UV activation
FAQ
Can the EQ-EVP24 be used with LC-MS-compatible solvents such as formic acid–water or ammonium acetate buffers?
Yes—provided the final concentration step occurs after buffer exchange or desalting; prolonged exposure to high concentrations of non-volatile salts may require periodic chamber cleaning.
Is rotor imbalance compensation built into the system?
No—the unit requires manual balancing of tube loads prior to operation; symmetric loading across the 24-position rotor is mandatory for safe centrifugation.
Does PriboLab supply validated IQ/OQ protocols for this concentrator?
PriboLab provides a basic user manual and mechanical verification checklist; full qualification documentation must be developed in-house per ISO/IEC 17025 or FDA guidance, leveraging the device’s deterministic control parameters.
What maintenance is required for long-term reliability?
Annual inspection of O-rings, periodic cleaning of the chamber interior with isopropanol, and verification of dry-block thermal uniformity using NIST-traceable probe thermometers are recommended.
