Shimadzu QP2010 Used Gas Chromatography-Mass Spectrometry (GC-MS) System
| Brand | Shimadzu |
|---|---|
| Origin | Japan |
| Manufacturer Type | Authorized Distributor |
| Origin Category | Imported |
| Model | QP2010 |
| Instrument Type | Triple Quadrupole Mass Spectrometer |
| GC Type | Conventional GC-MS |
| Mass Range | 1–1000 m/z |
| Resolution | 1000–2000 (unit mass resolution) |
| Sensitivity | >300:1 (S/N, full-scan, 1 pg octafluoronaphthalene) |
| Scan Speed | 150,000 u/s |
Overview
The Shimadzu QP2010 is a high-performance, used gas chromatography-mass spectrometry (GC-MS) system engineered for routine and trace-level organic compound identification and quantification in regulated and research laboratories. As a triple quadrupole (QqQ) mass spectrometer coupled with the GC-2010 gas chromatograph, it operates on tandem mass spectrometry (MS/MS) principles—enabling selective reaction monitoring (SRM), multiple reaction monitoring (MRM), and enhanced specificity in complex matrices. The system employs electron ionization (EI) and optional chemical ionization (CI) sources, delivering robust spectral reproducibility and high mass accuracy across its 1–1000 m/z range. Its design emphasizes analytical reliability under sustained operation, with hardware optimized for long-term stability in QC, environmental testing, food safety, and forensic applications.
Key Features
- Triple quadrupole architecture for high-selectivity MS/MS analysis, supporting SRM/MRM workflows with low background interference
- GC-2010 capillary gas chromatograph featuring rapid oven cooling (≤3.5 min from 300 °C to 50 °C), AFT (Advanced Flow Technology) for precise carrier gas control, and integrated backflush capability to minimize column contamination and extend maintenance intervals
- High-sensitivity detection: >300:1 signal-to-noise ratio (S/N) in full-scan mode using 1 pg of octafluoronaphthalene (OFN), validated per ASTM D5845 and ICH Q2(R2) guidelines
- Scan speed up to 150,000 u/s enables comprehensive peak capture across narrow chromatographic peaks, critical for fast-GC and multi-analyte screening
- Resolution of 1000–2000 (measured at 5% valley between adjacent masses) ensures reliable isotopic pattern recognition and interference-free quantitation
- Modular configuration includes AOC-20i autosampler with 100-position AOC-20s sample tray, split/splitless capillary inlet, and dedicated EI source with filament auto-tuning
Sample Compatibility & Compliance
The QP2010 accommodates volatile and semi-volatile organic compounds—including pesticides, PAHs, PCBs, residual solvents, and pharmaceutical impurities—across liquid, solid, and gaseous sample types following appropriate extraction (e.g., SPE, LLE, headspace) and derivatization protocols. It supports compliance with ISO/IEC 17025:2017 method validation requirements and aligns with data integrity expectations outlined in FDA 21 CFR Part 11 when deployed with Shimadzu’s LabSolutions GCMS software configured for audit trail, electronic signatures, and user access controls. System suitability testing (SST) parameters—including retention time stability (±0.02 min), peak area RSD (<3%), and mass calibration drift (<0.1 u over 24 h)—are routinely verified per USP and EP 2.2.48.
Software & Data Management
LabSolutions GCMS ver. 5.x provides full instrument control, real-time data acquisition, library search (NIST, Wiley, custom libraries), and quantitative report generation. The software supports GLP/GMP-compliant workflows through configurable user roles, secure audit trails, and raw data encryption. All acquisition methods, processing parameters, and calibration files are stored with metadata timestamps and operator IDs. Raw data (.qgd format) is non-proprietary and exportable to ASCII or mzML for third-party reprocessing. Optional add-ons include AutoSIM for targeted quantitation and Method Scouting for automated parameter optimization.
Applications
- Environmental analysis: Quantification of EPA Method 8270 analytes (SVOCs) and 8082 (PCBs) in soil, water, and air samples
- Food safety: Multi-residue pesticide screening per EU SANTE/11813/2021 guidelines
- Pharmaceutical QC: Residual solvent testing (ICH Q3C), genotoxic impurity verification, and extractables/leachables profiling
- Forensic toxicology: Confirmation of controlled substances and metabolites in biological matrices (urine, blood)
- Polymer additive analysis: Identification of plasticizers, antioxidants, and flame retardants via thermal desorption-GC/MS
FAQ
Is the QP2010 compliant with 21 CFR Part 11 for regulated environments?
Yes—when operated with LabSolutions GCMS v5.x under validated configurations including electronic signatures, audit trail logging, and role-based access control.
What maintenance documentation is included with this used system?
Full service history, last calibration certificate (mass axis, sensitivity, resolution), and OEM preventive maintenance logs are provided upon request.
Can the system be upgraded to support GC×GC or API sources?
No—the QP2010 platform is not compatible with comprehensive two-dimensional GC or atmospheric pressure ionization interfaces; it is strictly configured for EI/CI with capillary GC coupling.
What is the typical uptime and mean time between failures (MTBF) for a refurbished QP2010?
Refurbished units undergo 72-hour operational burn-in and component-level replacement (filaments, detector dynodes, vacuum pumps); MTBF exceeds 1,200 hours under standard operating conditions.
Does the system include original Shimadzu installation qualification (IQ) and operational qualification (OQ) protocols?
Yes—standard IQ/OQ templates aligned with ISO/IEC 17025 and ASTM E2500-07 are supplied; site-specific execution requires qualified field service engineer support.
