Chengmeng CM-12 Water Bath Nitrogen Evaporator

Overview

The Chengmeng CM-12 Water Bath Nitrogen Evaporator is an engineered solution for controlled, gentle solvent removal in analytical laboratories. It operates on the principle of inert gas-assisted surface evaporation: nitrogen or compressed air is delivered via adjustable stainless-steel needles positioned just above the liquid meniscus of each sample vessel, while simultaneous water bath heating maintains precise thermal energy input. This dual-mode (gas flow + conductive heating) configuration ensures reproducible concentration kinetics without thermal degradation—critical for thermolabile analytes in pesticide residue, pharmaceutical, environmental, and clinical matrices. Designed for compliance-driven workflows, the CM-12 supports method validation under ISO/IEC 17025, USP , and EPA Method 505/525 series protocols where consistent evaporation rate, positional temperature uniformity, and operator traceability are mandatory.

Key Features

• 12-position modular sample platform with engraved numeric identifiers and spring-loaded, height-adjustable tube clamps—compatible with round-bottom test tubes (Φ10–29 mm), centrifuge tubes, and conical vials (1–50 mL capacity).
• Independent vertical positioning of each gas needle (200 mm travel range) enables optimal distance-to-meniscus alignment across varying vessel heights and solvent volumes.
• Dual-gas manifold with separate N₂ and air inlets; each channel equipped with a precision SMC-branded flow control valve for individual sample-level gas regulation (0–15 L/min total, ~330 mL/min per position).
• Circular 304 stainless steel water bath (Φ260 × 150 mm) featuring PID-controlled digital thermostating (ambient +5 °C to 99 °C), ±0.5 °C stability, and ±0.1 °C display resolution—calibrated to meet ASTM E220 standards for laboratory temperature equipment.
• Integrated safety architecture: automatic dry-run shutoff, over-temperature cut-off, and fuse-protected 1000 W heating element (250 V / 8 A).
• Chemically resistant construction throughout—including SMC TUS fluoropolymer gas delivery tubing (non-leaching, halogen-free, compliant with USP Class VI biocompatibility requirements).
• Compact footprint (390 × 300 × 850 mm) optimized for fume hood integration; full assembly operates safely under negative pressure environments during volatile or toxic solvent processing.

Sample Compatibility & Compliance

The CM-12 accommodates standard analytical glassware and polypropylene consumables used in regulated QC/QA labs, including 13 × 100 mm, 16 × 150 mm, and 18 × 150 mm test tubes, as well as 15 mL and 50 mL centrifuge tubes. Its uniform thermal field (≤ ±0.5 °C deviation at 60 °C) satisfies ISO 17025 clause 6.4.3 for equipment suitability verification. The system is routinely deployed in GLP-compliant residue analysis (e.g., SANTE/11312/2021), pharmacopeial dissolution testing (USP ), and EPA-certified water testing labs—where instrument logs, temperature calibration records, and gas flow consistency must be auditable. No software-based electronic records are generated natively; however, analog timer outputs and manual log sheets fulfill basic 21 CFR Part 11 “paper-based record” equivalency when paired with lab SOPs.

Software & Data Management

The CM-12 operates via embedded hardware controls only—no proprietary software, cloud connectivity, or firmware updates are required or supported. All operational parameters (set temperature, timer duration, gas on/off status) are managed through the front-panel LCD interface with tactile buttons. Time and temperature values are retained post-power-cycle. For laboratories requiring documented traceability, users may integrate external data loggers (e.g., Omega OM-EL-USB-1) via the bath’s analog temperature output port (if available on custom-configured units) or maintain manual calibration logs per ISO/IEC 17025 Section 7.7. The absence of networked components eliminates cybersecurity risks and simplifies IQ/OQ/PQ validation for GMP-regulated facilities.

Applications

• Agrochemical Residue Analysis: Rapid concentration of QuEChERS extracts from fruits, vegetables, cereals, and plant tissues prior to GC-MS/MS or LC-MS/MS injection.
• Pharmaceutical Quality Control: Solvent exchange and final volume adjustment in herbal extract purification, dissolution media preparation, and stability-indicating assay sample prep.
• Environmental Monitoring: Pre-concentration of EPA Method 525.3 target compounds (PAHs, PCBs, organochlorines) from drinking water, wastewater, and sediment extracts.
• Clinical & Forensic Toxicology: Ethanol-free evaporation of plasma, urine, and whole blood samples containing benzodiazepines, opioids, or stimulants—minimizing analyte loss via oxidation or hydrolysis.
• Food Safety Testing: Preparation of milk, wine, juice, and edible oil samples for dioxin, furan, and mycotoxin quantification per EU Commission Regulation (EC) No 1881/2006.

FAQ

Is the CM-12 compatible with corrosive solvents such as chloroform or DCM?
Yes—the entire wetted path (bath, rack, needles, and SMC TUS tubing) is chemically inert to common organic solvents, including halogenated hydrocarbons, esters, and alcohols. Avoid prolonged exposure to strong oxidizers (e.g., concentrated nitric acid) or alkalis >pH 12.
Can I calibrate the temperature sensor myself?
The unit includes a calibrated PT100 sensor traceable to NIST standards. Users may verify accuracy using a certified reference thermometer (e.g., Fluke 1523) immersed at bath center; adjustment requires factory service.
What maintenance is required for long-term reliability?
Monthly inspection of gas fittings, cleaning of bath interior with deionized water, and visual check of tubing integrity. Replace SMC TUS tubing annually or after 500 operating hours—whichever occurs first.
Does the CM-12 support method transfer from older nitrogen evaporators?
Yes—its standardized 12-position geometry, consistent gas distribution profile, and programmable timer allow direct protocol migration from Thermo Fisher Reacti-Therm, Biotage Spe-ed, or Organomation N-EVAP systems without revalidation of evaporation efficiency.
Is there an optional data logging or remote monitoring module?
No native option exists; however, third-party USB temperature loggers with analog input capability can be connected externally for continuous bath temperature recording during unattended runs.