Organomation N-VEAP-45 Nitrogen Evaporator

Overview

The Organomation N-VEAP-45 Nitrogen Evaporator is a precision-engineered, benchtop solvent evaporation system designed for high-throughput, reproducible concentration of analytical samples under inert nitrogen atmosphere. It operates on the principle of controlled gas-phase solvent removal: nitrogen gas—delivered via individually adjustable, stainless-steel吹气针 (gas delivery needles)—is directed tangentially across the surface of heated liquid samples, accelerating solvent volatilization while minimizing oxidation, foaming, and cross-contamination. Unlike open-air drying or vacuum centrifugation, the N-VEAP-45 employs a thermostatically regulated water bath to provide uniform, gentle thermal energy transfer—critical for thermolabile analytes such as steroids, pesticides, pharmaceutical metabolites, and clinical biomarkers. Its modular architecture supports seamless integration into GLP-compliant workflows in regulated laboratories, where trace-level recovery, inter-batch consistency, and audit-ready operation are mandatory.

Key Features

• 45-position sample capacity with independent, rotatable sample block—enabling ergonomic front-access loading and unloading without repositioning the instrument.
• Programmable water bath heating system (0–99 °C) with ±0.5 °C temperature stability and digital PID control, ensuring minimal thermal gradient across all positions.
• Dual-stage gas regulation: inlet pressure acceptance from 30–150 psig; fine-tuned output control (0–30 psig) via calibrated needle valves integrated into each gas channel.
• Low-consumption nitrogen delivery: 330 mL/min per sample at optimal flow, reducing operational cost and cylinder replacement frequency without compromising evaporation efficiency.
• Laboratory-grade construction—including borosilicate glass-compatible sample holders, PTFE-sealed gas manifolds, and corrosion-resistant stainless-steel chassis—ensuring compatibility with chlorinated solvents, acetonitrile, methanol, ethyl acetate, and other common extraction media.
• Modular design accommodates optional dry-block heater upgrades and interchangeable sample blocks for tubes (10–30 mm OD), conical vials, centrifuge tubes, and culture tubes.

Sample Compatibility & Compliance

The N-VEAP-45 supports a broad range of sample containers—including 10–30 mm outer-diameter test tubes, 15 mL and 50 mL centrifuge tubes, 125 mL Erlenmeyer flasks, and 250 mL round-bottom flasks—without adapter modification. Its inert gas environment complies with ASTM D5866-21 (for pesticide residue analysis), EPA Method 525.3 (drinking water contaminants), and USP residual solvent testing requirements. All electronic controls meet IEC 61010-1 safety standards for laboratory equipment. The unit is compatible with 21 CFR Part 11–enabled LIMS environments when paired with validated third-party data logging software, supporting full traceability of temperature setpoints, run duration, and gas pressure logs for GMP/GLP audits.

Software & Data Management

While the N-VEAP-45 operates as a stand-alone analog-controlled system, its temperature and gas parameters are fully monitorable and recordable via external digital interfaces. Optional RS-232 or USB-to-serial adapters enable real-time acquisition of bath temperature and elapsed time into compliant data acquisition platforms (e.g., LabArchives, Empower, or custom Python-based scripts). All hardware components—including the analog temperature controller, mechanical pressure gauges, and calibrated flow meters—are designed for long-term calibration stability, with annual verification recommended per ISO/IEC 17025:2017 Clause 6.5. Calibration certificates are available upon request for metrological traceability to NIST standards.

Applications

• Residue analysis: Multi-residue pesticide screening in fruits, vegetables, cereals, and plant tissues per AOAC 2007.01 and EN 15662.
• Environmental monitoring: Concentration of PAHs, PCBs, dioxins, and chlorinated hydrocarbons from drinking water, groundwater, and wastewater matrices (EPA 8270, 8082).
• Pharmaceutical QC: Residual solvent removal prior to HPLC/GC-MS analysis of APIs, herbal extracts, and finished dosage forms.
• Clinical toxicology: Preparation of serum, plasma, urine, and whole blood samples for LC-MS/MS quantification of drugs of abuse, endogenous hormones, and therapeutic drug monitoring panels.
• Food safety: Detection of mycotoxins (aflatoxin B1, ochratoxin A), veterinary drug residues, and process contaminants (e.g., furan, acrylamide) in milk, wine, and liquid beverages.

FAQ

Is the N-VEAP-45 compatible with organic solvents such as hexane, chloroform, and acetone?

Yes—the entire fluid path, including gas manifolds, needle valves, and sample support hardware, is constructed from chemically resistant materials (316 stainless steel, PTFE, borosilicate glass) rated for continuous exposure to common organic solvents.
Can the unit be operated without nitrogen gas supply?

No. Nitrogen (or another inert gas) is essential for both solvent displacement and oxidation prevention. Compressed air is not recommended due to moisture and oxygen content.
What maintenance is required for long-term reliability?

Monthly inspection of O-rings and needle valve seats; biannual cleaning of water bath chamber and descaling if used with tap water; annual verification of temperature sensor accuracy using a NIST-traceable thermometer.
Does the N-VEAP-45 meet FDA or ISO regulatory requirements for use in quality control labs?

The instrument itself is not “certified” but is engineered and documented to support compliance with ISO 17025, FDA 21 CFR Part 11 (when integrated with compliant software), and GMP Annex 11 requirements for equipment qualification (IQ/OQ/PQ protocols available upon request).
Is dry-block heating available as an alternative to water bath?

Yes—Organomation offers an optional dry-heating module (N-VEAP-DH45) with identical footprint and control interface, providing faster ramp rates and eliminating water management concerns.