Metash C6080R Floor-Standing High-Speed Refrigerated Centrifuge

Overview

The Metash C6080R is a floor-standing, high-speed refrigerated centrifuge engineered for precision separation of biological, clinical, and industrial samples under controlled thermal conditions. Designed around the principles of rotor dynamics and thermally stabilized sedimentation, it delivers consistent RCF (relative centrifugal force) performance up to 28,978 × g at 18,000 rpm—enabling efficient pelleting of subcellular organelles, viruses, macromolecular complexes, and particulate suspensions. Its robust architecture supports continuous operation over extended durations, with integrated thermal management ensuring stable chamber temperatures from −20 °C to +40 °C. The unit complies with IEC 61010-1 (Safety Requirements for Electrical Equipment for Measurement, Control, and Laboratory Use) and incorporates mechanical and electronic safety redundancies aligned with GLP-compliant laboratory workflows.

Key Features

• Brushless AC frequency-converter motor delivering high starting torque, low acoustic emission (≤58 dB[A]), and extended service life without carbon brush wear or commutator maintenance
• Dual-stage door interlock system combining electromagnetic feedback verification and mechanical latching—ensuring rotor containment during operation per ISO 13485 design controls
• Automatic rotor recognition via embedded RFID tags, eliminating manual input errors and enforcing speed/RCF limits specific to each certified rotor configuration
• Intelligent imbalance detection with real-time vibration monitoring; automatic shutdown triggered upon deviation exceeding ISO 21501-4 threshold limits
• Three-phase active cooling using R-134a refrigerant and 360° circumferential airflow distribution—achieving uniform temperature gradients across the entire rotor cavity
• Programmable deceleration profiles (10 selectable ramps), including “free deceleration” mode to prevent resuspension of delicate pellets such as mitochondrial fractions or cryoprecipitated proteins
• Integrated pre-cooling function with audible and visual completion alerts—reducing time-to-run latency between sample loading and initiation of separation

Sample Compatibility & Compliance

The C6080R accommodates standard horizontal rotors supporting up to four 250 mL conical tubes (e.g., polypropylene or polycarbonate), compatible with common biosafety level 2 (BSL-2) sample containers. It accepts all Metash-certified swinging-bucket rotors—including those validated for blood bag processing, cell culture harvest, and nucleic acid purification workflows. All rotor assemblies undergo dynamic balancing per ISO 1940-1 G2.5 grade certification and are traceable to individual serial numbers. The instrument meets CE marking requirements under the EU Machinery Directive 2006/42/EC and Electromagnetic Compatibility Directive 2014/30/EU. Optional audit trail logging supports 21 CFR Part 11 compliance when paired with Metash LabManager™ software (sold separately).

Software & Data Management

A 5.7-inch color LCD interface provides intuitive navigation through setup menus, real-time parameter display (speed, RCF, time remaining, chamber temperature, acceleration/deceleration stage), and diagnostic status codes. Thirty user-defined protocols can be saved with full parameter recall—including temperature setpoint, run duration, acceleration/deceleration ramp selection, and auto-restart behavior after power interruption. Time-to-speed countdown timer initiates timing only after target rpm is achieved—critical for reproducible kinetic studies. Exportable run logs (CSV format) include timestamped metadata: operator ID, rotor ID, cycle count, thermal deviation history, and safety event flags—facilitating internal QA review and external regulatory audits.

Applications

• Clinical diagnostics: Separation of serum/plasma from whole blood at standardized g-forces for ELISA, coagulation assays, and therapeutic drug monitoring
• Biopharmaceutical development: Harvesting mammalian cell cultures (CHO, HEK293) and clarifying monoclonal antibody supernatants prior to chromatography
• Academic research: Isolation of exosomes, microvesicles, and ribonucleoprotein complexes via differential ultracentrifugation protocols
• Food & beverage QC: Determination of fat content in milk homogenates and detection of adulterants in plant-based emulsions
• Environmental testing: Concentration of microbial cells or microplastics from large-volume water samples (up to 1 L total per run)

FAQ

What rotor types are compatible with the C6080R?
The C6080R supports all Metash-certified horizontal rotors rated for ≤18,000 rpm and ≤28,978 × g, including 4×250 mL, 6×100 mL, and 8×50 mL configurations. Each rotor includes an embedded RFID tag for automatic identification and safety-enforced parameter binding.
Does the C6080R meet FDA or ISO standards for regulated environments?
Yes—the unit conforms to ISO 13485:2016 design controls, IEC 61010-1 safety standards, and CE directives. When used with optional audit-trail-enabled software, it supports data integrity requirements outlined in FDA 21 CFR Part 11 and EU Annex 11.
Can the centrifuge maintain −20 °C during prolonged runs?
Yes—its dual-circuit R-134a refrigeration system and insulated chamber wall construction ensure sustained temperature stability within ±1 °C across 99-minute continuous operation at maximum load.
Is remote monitoring or network integration available?
Local Ethernet connectivity is supported for firmware updates and log export. Full SCADA or LIS integration requires third-party middleware; Metash provides documented API endpoints for custom integration projects.
How often does the refrigeration system require maintenance?
Under normal usage (≤8 hrs/day, ambient ≤30 °C), compressor service intervals exceed 10,000 operating hours. Annual inspection of condenser coils and refrigerant pressure calibration is recommended per manufacturer guidelines.