Analytik Jena Cybi-FeliX Universal Automated Liquid Handling Workstation
| Brand | Analytik Jena |
|---|---|
| Origin | Germany |
| Model | Cybi-FeliX |
| Dimensions | 650 × 450 mm |
| Working Volume Range | 0.5–1000 µL |
| Plate Positions | 12 |
| Liquid Handling Technology | CHOICE™ Precision Air Displacement with CyBi®-TipTray Sealed Tip Exchange |
| Software Interface | Graphical, Script-Free Protocol Builder |
| Compliance | Designed for GLP/GMP environments |
Overview
The Analytik Jena Cybi-FeliX Universal Automated Liquid Handling Workstation is an integrated, benchtop liquid handling platform engineered for precision, flexibility, and space efficiency in modern life science and analytical laboratories. Built upon CyBio’s proprietary CHOICE™ (Controlled High-precision Operation with Integrated Cartridge Exchange) air-displacement technology, the Cybi-FeliX delivers consistent volumetric accuracy across an exceptionally wide dynamic range—0.5 µL to 1000 µL—using a single, interchangeable pipetting head. Unlike conventional multi-head or fixed-range systems, this architecture eliminates manual tip head swaps during protocol execution, reducing both operational complexity and risk of cross-contamination. The workstation operates on a rigid, vibration-damped aluminum frame and integrates real-time pressure monitoring and automatic tip seal verification via CyBi®-TipTray—a patented, gas-tight tip exchange mechanism that ensures reproducible aspiration and dispense performance across all volumes and liquid classes (aqueous, viscous, volatile, or low-retention). Its compact footprint (650 × 450 mm) accommodates 12 standardized deck positions, enabling simultaneous use of microplates (96-, 384-, and 1536-well), tube racks, reservoirs, and ancillary modules without spatial compromise.
Key Features
- Single-head, ultra-wide volume range (0.5–1000 µL) enabled by CHOICE™ cartridge-based actuation and adaptive piston calibration
- Automated liquid handling adapter switching—no physical head replacement required for mode transitions (single-channel, row-wise, column-wise, or full-plate dispensing)
- CyBi®-TipTray system: fully automated, sealed-tip loading/unloading with integrated vacuum-assisted tip ejection and real-time seal integrity check
- 12-position programmable deck with modular mounting rails compatible with ANSI/SLAS-standard labware and third-party accessories
- High-precision Z-axis control (±0.05 mm repeatability) and optimized liquid-level sensing for accurate bottom-touch and surface-following operations
- Onboard barcode reader (optional) for sample tracking and full traceability within LIMS-integrated workflows
Sample Compatibility & Compliance
The Cybi-FeliX handles diverse liquid types—including aqueous buffers, glycerol-containing solutions (up to 50% v/v), DMSO-based compounds, and low-surface-tension solvents—without requiring hardware reconfiguration. Its air-displacement architecture incorporates temperature-compensated piston calibration and humidity-adaptive evaporation correction algorithms. From a regulatory perspective, the system is architected to support compliance with ISO/IEC 17025, CLIA, and GxP frameworks. Software features include role-based user authentication, electronic signatures, immutable audit trails, and protocol version control—all aligned with FDA 21 CFR Part 11 and EU Annex 11 requirements. Instrument qualification documentation (IQ/OQ/PQ templates) and calibration certificates are provided per Analytik Jena’s quality management system (ISO 9001 certified).
Software & Data Management
The Cybi-FeliX is operated via CyBi-Script™, a visual, drag-and-drop protocol development environment with no coding prerequisite. Users construct workflows using intuitive icons representing liquid transfer, mixing, serial dilution, plate replication, and conditional logic steps. All protocols are stored with metadata (operator ID, timestamp, instrument serial number, calibration status) and exportable in CSV, XML, or PDF formats. The software supports direct integration with major laboratory information management systems (LIMS) and electronic lab notebooks (ELN) through standard APIs (RESTful HTTP and OPC UA). Raw log files—including pressure transients, motor encoder counts, and tip seal validation results—are retained for forensic analysis during method validation or deviation investigations.
Applications
- High-throughput assay setup (ELISA, qPCR, cell-based assays)
- Serial dilution series generation with ≤2% CV at 1 µL and ≤0.5% CV at ≥100 µL
- Compound library reformatting (e.g., 384-to-1536-well plate transfers)
- Automated nucleic acid normalization and library preparation for NGS workflows
- QC sample preparation for HPLC, LC-MS, and ICP-MS analysis
- Cell culture media supplementation and bioprocess intermediate sampling
FAQ
Does the Cybi-FeliX require regular recalibration of its pipetting head?
Yes—Analytik Jena recommends quarterly volumetric verification using gravimetric methods per ISO 8655-6, with full calibration every 12 months or after mechanical maintenance.
Can the system be integrated into a robotic arm–based automation suite?
Yes—the Cybi-FeliX features RS-232, Ethernet, and digital I/O interfaces for synchronization with third-party robotic platforms and conveyor systems.
Is tip reuse supported for cost-sensitive applications?
No—CyBi®-TipTray is designed exclusively for single-use, sterile, filtered tips to maintain assay integrity and comply with ISO 5840 and USP endotoxin testing standards.
What level of technical support is available outside the EU?
Analytik Jena provides global service coverage through authorized partners, including remote diagnostics, on-site engineering support, and scheduled preventive maintenance contracts.
