Beifen Sanpu WHY-2A Refrigerated Water Bath Orbital Shaker
| Brand | Beifen Sanpu |
|---|---|
| Origin | Hebei, China |
| Manufacturer Type | Direct Manufacturer |
| Product Category | Domestic |
| Model | WHY-2A |
| Instrument Type | Refrigerated Water Bath Orbital Shaker |
| Timer Range | 0–120 min |
| Oscillation Frequency | 0–300 rpm (adjustable) |
| Oscillation Amplitude | 20 mm |
| Temperature Control Range | 0–100 °C (with active refrigeration) |
| Platform Quantity | 1 |
Overview
The Beifen Sanpu WHY-2A Refrigerated Water Bath Orbital Shaker is an engineered solution for precise temperature-controlled agitation of samples in aqueous or buffer-based environments. Designed specifically for solid-state compound handling—including dissolution testing, solubility profiling, crystallization studies, and stability assessment—the instrument integrates orbital shaking mechanics with a dual-mode (heating/cooling) water bath system. Its operation relies on a robust motor-driven eccentric drive mechanism that delivers smooth, uniform orbital motion (20 mm diameter), minimizing sample splashing while ensuring homogeneous thermal and mechanical energy transfer across vials, tubes, and multi-well plates. Unlike ambient-air shakers, the water bath design provides superior thermal uniformity (±0.3 °C typical at 37 °C) and dampens mechanical vibration transmission to adjacent equipment—critical in shared lab environments. The integrated refrigeration module enables sub-ambient operation down to 0 °C, supporting cold-sensitive enzymatic assays, protein refolding protocols, and low-temperature extraction workflows without external chillers.
Key Features
- Refrigerated water bath system with independent heating and cooling circuits, enabling stable setpoints from 0 °C to 100 °C
- Adjustable orbital speed range: 0–300 rpm with digital feedback control for repeatable rotational consistency
- Single-platform configuration with stainless steel tray (300 × 250 mm usable area) compatible with standard Erlenmeyer flasks (up to 2 L), centrifuge tubes, and microtiter plates
- Digital LED interface with real-time display of setpoint temperature, actual bath temperature, and current oscillation speed
- Precision timer (0–120 minutes) with auto-shutdown function; continuous operation mode also supported via manual override
- Over-temperature and dry-run protection safeguards both sample integrity and unit longevity
- Low-noise brushless DC motor and reinforced bearing assembly ensure >20,000 hours MTBF under routine laboratory use
Sample Compatibility & Compliance
The WHY-2A accommodates a broad spectrum of sample formats used in pharmaceutical development, analytical chemistry, and molecular biology—including but not limited to sealed glass vials, polypropylene centrifuge tubes (15–50 mL), screw-cap culture bottles, and deep-well microplates. Its water-immersed platform eliminates air-gap thermal resistance, making it especially suitable for temperature-sensitive solid-phase reactions where kinetic control is essential (e.g., polymorph screening per ICH Q1A(R3)). The unit conforms to general electrical safety requirements per GB 4793.1–2018 (equivalent to IEC 61010-1), and its construction materials meet ISO 10993-5 biocompatibility criteria for indirect contact with pharmaceutical intermediates. While not certified for GMP manufacturing environments out-of-the-box, the instrument supports GLP-compliant documentation when paired with external audit-trail-capable data loggers.
Software & Data Management
The WHY-2A operates as a standalone benchtop device with no embedded software stack or network connectivity. All operational parameters are controlled locally via front-panel buttons and displayed in real time. For laboratories requiring electronic records, analog output (0–5 V) for temperature and RPM signals is available upon request (optional accessory port), enabling integration with third-party data acquisition systems compliant with FDA 21 CFR Part 11—provided user-defined validation protocols are implemented. No proprietary firmware or cloud services are involved, eliminating cybersecurity concerns associated with connected instruments. Calibration certificates traceable to NIM (National Institute of Metrology, China) can be supplied separately for metrological verification.
Applications
- Solubility and dissolution rate determination of APIs and excipients per USP <711>
- Stability-indicating studies under ICH Q1A–Q1E conditions (e.g., 40 °C/75% RH simulated via controlled bath + humidity chamber)
- Extraction optimization for natural products using solvent-saturated aqueous phases
- Hydration kinetics of amorphous solid dispersions and co-crystals
- Preparation of uniformly dispersed nanoparticle suspensions prior to DLS or TEM analysis
- Antibody-antigen binding equilibration in ELISA plate wash steps requiring gentle agitation
FAQ
Does the WHY-2A support programming multiple temperature-speed profiles?
No. It features single-setpoint operation only. Multi-step protocols require manual adjustment or external controller integration.
Can the unit maintain 4 °C continuously for overnight incubations?
Yes—its refrigeration system is rated for sustained operation at 4 °C with ambient lab temperatures ≤25 °C and proper ventilation.
Is the water bath depth sufficient for submerging 50-mL conical tubes?
With standard fill level (12 cm bath depth), 50-mL tubes up to 12 cm tall may be partially submerged; full immersion requires optional elevated platform or custom rack.
What maintenance is required for long-term reliability?
Biannual descaling with 10% acetic acid solution (if using tap water) and annual inspection of refrigerant lines and seal integrity are recommended.
Is CE or UL certification available?
Not by default; however, units can be factory-modified to meet CE marking requirements (EN 61010-1, EN 61326-1) with additional lead time and documentation fees.
