Grant V-32 Multi-Function Vortex Mixer

Overview

The Grant V-32 Multi-Function Vortex Mixer is an engineered solution for rapid, reproducible sample homogenization in molecular biology, clinical diagnostics, and pharmaceutical quality control laboratories. Designed around a high-efficiency brushless DC motor and precision-machined eccentric drive mechanism, the V-32 delivers consistent orbital motion with a 2 mm orbit diameter—optimized for efficient mixing of low-volume samples without splashing or foaming. Unlike fixed-speed vortexers, the V-32 features continuously adjustable speed control from 500 to 3000 rpm, enabling users to fine-tune agitation intensity for sensitive applications such as DNA shearing minimization, enzyme reconstitution, or suspension of lyophilized reagents. Its compact footprint and 12 V DC power architecture support safe operation in biosafety cabinets, cold rooms, and ISO-classified cleanrooms where standard AC-powered equipment may pose electrical or thermal constraints.

Key Features

• Variable-speed orbital mixing (500–3000 rpm) with tactile rotary dial and LED speed indicator for precise parameter recall
• Single-platform design accommodating heterogeneous tube configurations: up to sixteen 1.5 mL, eight 0.5 mL, and eight 0.2 mL microcentrifuge tubes simultaneously
• 2 mm orbital displacement engineered to maximize fluidic shear while minimizing aerosol generation and tube wall adhesion
• Integrated 1-minute mechanical timer with auto-shutoff; also supports continuous operation via manual hold mode
• Low-voltage 12 V DC input ensures intrinsic electrical safety, reduced electromagnetic interference (EMI), and compatibility with uninterruptible power supplies (UPS) or battery backup systems
• Rugged polypropylene housing with chemical-resistant surface finish; IP20-rated for general laboratory environments
• No internal heating or cooling elements—designed strictly for ambient-temperature mixing to preserve thermolabile analytes

Sample Compatibility & Compliance

The V-32 is validated for use with standard conical-bottom and round-bottom microcentrifuge tubes (0.2–1.5 mL), including those made from polypropylene, polyethylene, and PCR-grade plastics. It does not support deep-well plates, culture flasks, or viscous samples (>100 mPa·s at 25 °C). While the device itself carries CE marking per Directive 2014/30/EU (EMC) and 2014/35/EU (LVD), it is classified as a Class I laboratory accessory under IEC 61010-1:2010. No regulatory certification (e.g., FDA 510(k), ISO 13485) applies, as the V-32 performs no diagnostic, analytical, or therapeutic function. Laboratories operating under GLP or GMP frameworks may include the V-32 in equipment qualification protocols (IQ/OQ) using documented speed verification (e.g., tachometer calibration traceable to NPL standards) and routine performance checks per SOP-LAB-VM-01.

Software & Data Management

The Grant V-32 operates as a standalone hardware device with no embedded firmware, network interface, or data logging capability. All operational parameters are set manually and retained only during active use. This analog control architecture eliminates cybersecurity risks, software validation requirements (e.g., FDA 21 CFR Part 11), and firmware update dependencies—making it suitable for regulated environments where audit trails for mixing parameters are maintained externally via lab notebook entries or LIMS-integrated electronic batch records. Speed settings are repeatable within ±15 rpm across ambient temperatures (5–40 °C), verified per Grant’s factory calibration certificate (included).

Applications

• Routine resuspension of pelleted cells, bacterial colonies, or precipitated nucleic acids prior to lysis or downstream amplification
• Homogenization of immunoassay reagents, ELISA standards, and antibody conjugates to ensure uniform antigen-binding site exposure
• Pre-analytical preparation of clinical specimens—including whole blood, serum, plasma, and CSF—for automated analyzers requiring homogeneous matrix distribution
• Supporting Good Manufacturing Practice (GMP) workflows in biopharmaceutical QC labs where consistent vortexing is specified in compendial methods (e.g., USP Analytical Instrument Qualification)
• Integration into automated liquid handling workcells via external relay control (optional 3.5 mm jack interface available on custom order)

FAQ

Is the V-32 compatible with 96-well plates?
No—the platform geometry and orbital dynamics are optimized exclusively for individual microcentrifuge tubes. Plate shaking requires dedicated orbital or linear shakers with plate clamps.
Can the V-32 be used inside a CO₂ incubator?
Not recommended. Although rated for 5–40 °C ambient operation, internal condensation and elevated humidity may compromise motor longevity and electrical insulation integrity.
Does Grant provide speed calibration services?
Yes—Grant Instruments UK offers annual speed verification and certification against NPL-traceable reference tachometers, delivered with a signed calibration report compliant with ISO/IEC 17025 requirements.
What maintenance is required?
None beyond periodic wiping of the platform with 70% ethanol; the brushless DC motor is sealed and maintenance-free for ≥10,000 hours of operation.
Is the power supply included?
Yes—a CE-certified 12 V DC, 1 A switching power adapter with interchangeable international plug options (UK, EU, US, AU) is supplied with each unit.