Zhengxin PFK-50mL Magnetic Stirring High-Pressure Reactor

Overview

The Zhengxin PFK-50mL Magnetic Stirring High-Pressure Reactor is a compact, precision-engineered laboratory-scale reaction system designed for controlled synthesis under elevated temperature and pressure conditions. Based on the fundamental principle of magnetic torque transmission through static pressure boundaries, this reactor eliminates mechanical shaft seals—reducing leakage risk and enabling hermetic containment of reactive, toxic, or oxygen-sensitive media. Its monolithic 304 stainless steel body, CNC-machined in a single setup, ensures dimensional stability and structural integrity across thermal cycling and pressure ramping protocols. The unit operates within a verified pressure envelope of 0–10 MPa and temperature range up to 350 °C, making it suitable for kinetic studies, catalytic screening, hydrogenation, supercritical fluid reactions, and inert-atmosphere polymerizations where reproducibility, trace contamination control, and operator safety are critical.

Key Features

• Monobloc reactor body machined from certified 304 stainless steel bar stock—no welds in pressure boundary, compliant with ASME BPVC Section VIII Div. 1 design principles for small-diameter vessels.
• Dual-stage sealing architecture: primary PTFE gasket combined with secondary metal-to-metal flange contact surface, rated for repeated thermal cycling between –20 °C and 350 °C.
• High-torque magnetic coupling using sintered NdFeB permanent magnets and brushless DC motor—enabling stable agitation up to 1,000 rpm without lubricant degradation or seal wear.
• Modular heating system with embedded aluminum-sheathed resistive elements and real-time K-type thermocouple feedback (316L sheath, Φ2.0 mm), delivering uniform thermal distribution and minimizing axial temperature gradients.
• Integrated safety interlocks: over-pressure burst disc (Hastelloy C-276, calibrated at 11 MPa), over-temperature cut-off (±1 °C accuracy), and programmable timer-based shutdown with audible/visual alerts via LCD interface.
• Flanged closure with 6-point M12 stainless steel bolts—designed for rapid assembly/disassembly while maintaining ASME-equivalent bolt preload consistency and gasket compression ratio.

Sample Compatibility & Compliance

This reactor supports heterogeneous and homogeneous reaction systems involving corrosive reagents (e.g., HCl, HF, concentrated H₂SO₄), organometallic catalysts, pyrophoric compounds, and high-boiling solvents (e.g., DMF, NMP, sulfolane). Optional liners—including PTFE, quartz, and PPL—extend compatibility to hydrofluoric acid and strong alkalis. All wetted surfaces meet USP Class VI and FDA 21 CFR Part 11–compatible documentation standards for GMP-aligned process development. Pressure vessel certification follows China’s NB/T 47003.1–2009 (equivalent to EN 13445-1) for unfired pressure equipment; electrical components comply with IEC 61000-6-3 EMC requirements.

Software & Data Management

The embedded controller supports dual-channel PID regulation with ramp/soak programming (optional PC interface via RS485/Modbus RTU). Temperature and pressure logs are timestamped and stored internally (≥10,000 data points) with export capability to CSV format. Audit trail functionality records all parameter changes, alarm events, and manual overrides—fully traceable for GLP/GMP validation. Optional LabVIEW or Python SDK enables integration into automated reaction platforms compliant with ASTM E2515–18 (Standard Guide for Automated Reaction Screening).

Applications

• Catalyst testing under realistic process conditions (e.g., Fischer–Tropsch, hydrodesulfurization, asymmetric epoxidation)
• High-pressure hydrogenation of fine chemicals and pharmaceutical intermediates
• Supercritical CO₂-mediated extractions and reactions
• Thermal stability assessment of battery electrolytes and solid-state ion conductors
• Accelerated aging studies of polymers and composites under inert gas (N₂, Ar) or reducing (H₂) atmospheres
• Microscale optimization of continuous-flow chemistry parameters prior to pilot-scale transfer

FAQ

What is the maximum allowable working pressure for the PFK-50mL model?

The reactor is rated for continuous operation up to 10 MPa (1,450 psi) gauge pressure at 200 °C; the burst disc is calibrated to activate at 11 MPa.

Can the unit be operated under vacuum prior to pressurization?

Yes—it achieves ≤–0.1 MPa (absolute) vacuum via integrated VCR-compatible ports, verified per ISO 2859–1 sampling plan for leak integrity.

Is third-party calibration documentation available?

Factory calibration certificates for temperature (NIST-traceable K-type sensor) and pressure (digital transducer, ±0.25% FS) are supplied with each unit; ISO/IEC 17025 accredited recalibration services are offered.

How is stirring speed controlled and monitored?

Speed is set digitally (0–1000 rpm, 1-rpm resolution) and continuously monitored via Hall-effect tachometer feedback; no slippage occurs due to optimized magnet geometry and torque coupling efficiency >92%.

Are custom configurations—such as Hastelloy C-22 body or sapphire viewport—supported?

Yes. Zhengxin provides engineering consultation and ASME-stamped fabrication for materials upgrades, specialized instrumentation ports (e.g., Raman feedthroughs), and DIN/ISO flange adaptations upon request.