Zhichu ZQWY-218 Horizontal Large-Capacity Full-Temperature Orbital Shaker

Overview

The Zhichu ZQWY-218 Horizontal Large-Capacity Full-Temperature Orbital Shaker is an engineered platform for controlled microbial growth, cell culture expansion, and biochemical incubation under precisely regulated thermal and mechanical conditions. Designed for laboratory-scale bioprocessing, it integrates orbital shaking motion with full-range refrigerated heating—enabling continuous operation from near-refrigeration (4 °C) to elevated physiological temperatures (60 °C). Its three-tier horizontal shaker configuration supports high-throughput cultivation across diverse vessel formats, while the P.I.D. microcomputer temperature control system ensures ±0.1 °C setpoint accuracy and ±1 °C uniformity at 37 °C—a critical requirement for reproducible aerobic fermentation and suspension-based mammalian or bacterial culture. The unit employs a three-dimensional eccentric triple-cam drive mechanism to deliver smooth, low-vibration orbital motion with minimal harmonic resonance, preserving sample integrity over extended incubation periods.

Key Features

• Triple-shelf horizontal architecture supporting up to 3 independent platforms, each accommodating standard flask configurations including 250 mL × 66, 500 mL × 45, or 5 L × 8 per shelf (stainless steel clamps)
• High-precision servo motor with ±1 rpm speed regulation; selectable forward/reverse rotation mode for specialized mixing protocols
• LCD capacitive touchscreen interface displaying real-time setpoints and measurements (temperature, speed, remaining time) on a unified screen; password-protected operation lockout prevents unauthorized parameter changes
• Intelligent refrigeration system featuring imported hermetic compressor, eco-friendly R134a refrigerant, and adjustable cooling capacity for stable sub-ambient performance
• Programmable defrost cycle: duration 1–250 s, interval 30–600 min—prevents evaporator icing during prolonged low-temperature operation
• UV germicidal lamp integrated into chamber ceiling for routine sterilization between runs; stainless steel interior with R-corner polishing and electropolished finish to inhibit biofilm formation
• Acoustic optimization: noise level <55 dB(A) at 1 m distance; silent centrifugal fan with forced-air convection ensures rapid thermal equilibration and homogeneity
• Power-fail recovery function retains all active parameters and resumes operation post-interruption; automatic over-temperature cutoff and fault-triggered shutdown enhance operational safety

Sample Compatibility & Compliance

The ZQWY-218 accommodates a broad spectrum of culture vessels—including Erlenmeyer flasks (250–5000 mL), test tubes, deep-well plates, and custom bioreactor bags—via modular clamp systems (standard Φ26 mm polymer clamps; optional Φ50 mm heavy-duty fixtures). Its 1050 mm × 530 mm shelf dimensions and 495 mm clearance from clamp plate to chamber ceiling allow flexible stacking of tall vessels. The unit complies with IEC 61010-1:2010 for laboratory equipment safety and meets electromagnetic compatibility standards per EN 61326-1:2013 (including ferrite magnetic ring filtering). While not certified for ISO Class 5 cleanroom use, its sealed chamber design, UV sterilization capability, and non-porous stainless steel interior support GLP-aligned workflows in QC microbiology and upstream process development labs.

Software & Data Management

Onboard data logging records temperature, speed, and elapsed time at one-minute intervals, retaining up to 90 days of continuous traceability without external storage. Logged datasets—including temporal profiles of both setpoint and actual values—are exportable via USB 2.0 port in CSV format for downstream analysis in MATLAB, Python Pandas, or LIMS environments. The system supports audit-ready timestamping and does not overwrite historical logs unless manually cleared. Though lacking native network connectivity or FDA 21 CFR Part 11-compliant electronic signatures, its deterministic logging architecture facilitates integration into validated environments when paired with qualified third-party data acquisition software meeting ALCOA+ principles.

Applications

• Aerobic microbial culture (E. coli, yeast, actinomycetes) under scalable agitation and temperature regimes
• Suspension-adapted CHO or HEK293 cell line expansion prior to bioreactor inoculation
• Enzyme production and protein expression studies requiring precise thermal and kinetic control
• Environmental microbiology assays—including BOD testing and biodegradation kinetics—where oxygen transfer rate correlates with orbital amplitude and frequency
• Antibiotic susceptibility screening using broth microdilution in shaken liquid media
• Preparation of competent cells, phage lysates, and plasmid preps where consistent shear stress minimizes DNA degradation

FAQ

What is the maximum flask size supported per shelf?
Each shelf supports up to eight 5 L flasks or fourteen 3 L flasks using stainless steel universal clamps.
Is the temperature calibration traceable to NIST standards?
The unit includes internal calibration offset adjustment; external verification using NIST-traceable thermistors is recommended annually per ISO/IEC 17025 guidelines.
Can the shaker operate continuously at 4 °C for >72 hours?
Yes—the programmable defrost logic and high-efficiency compressor enable uninterrupted low-temperature operation, validated for 168-hour stability at 4 °C.
Does the USB interface support firmware updates?
No; the USB port is read-only for data export. Firmware revisions require authorized service technician intervention.
Are replacement clamps available for non-standard vessel geometries?
Custom-machined aluminum and polypropylene clamp inserts are available upon request with dimensional specifications.