Titan HLD-100 Integrated Dynamic Heating and Cooling Circulating Chiller

Overview

The Titan HLD-100 is an integrated dynamic heating and cooling circulating chiller engineered for high-precision thermal control in demanding laboratory and pilot-scale applications. Unlike conventional single-function chillers or bath circulators, the HLD-100 employs a dual-mode thermodynamic architecture—combining a high-efficiency air-cooled refrigeration circuit with a high-power resistive heating system—to deliver seamless, bidirectional temperature regulation across an exceptionally wide operational range of −40 °C to +200 °C. Its design adheres to fundamental principles of closed-loop fluid thermoregulation, where temperature-controlled heat transfer fluid (typically water–glycol mixtures or silicone oils) is continuously circulated under pressure to external equipment such as reactor jackets, calorimeters, spectroscopic cells, or material testing stages. The unit’s continuous-duty operation mode ensures uninterrupted thermal conditioning during extended experiments, while its ±0.1 °C temperature stability meets stringent requirements for kinetic studies, polymer processing validation, and pharmaceutical stability testing.

Key Features

• Integrated dual-function design: Simultaneous heating and cooling capability eliminates the need for separate hot/cold units, reducing footprint and inter-system calibration drift.
• Air-cooled refrigeration system: Eliminates dependency on facility cooling water; suitable for labs without chilled water infrastructure or with limited utility access.
• High-flow, high-pressure circulation: Delivers up to 110 L/min at 5.5 bar, enabling effective thermal coupling with large-volume jackets, multi-zone reactors, or high-thermal-mass instrumentation.
• Precision temperature control: Digital PID algorithm with adaptive tuning maintains ±0.1 °C stability over full range—validated per ASTM E743 and ISO 17025 traceable protocols.
• Robust 20 L reservoir with level monitoring and low-fluid safety cutoff: Prevents pump cavitation and overheating during prolonged operation.
• Industrial-grade construction: Stainless-steel fluid pathways, corrosion-resistant heat exchangers, and IP54-rated electrical enclosure ensure long-term reliability in QC/QA and GLP-compliant environments.

Sample Compatibility & Compliance

The HLD-100 is compatible with a broad spectrum of heat transfer media—including aqueous glycol solutions (up to 50% v/v), silicone oils (e.g., DC200 series), and specialized low-temperature fluids—enabling safe operation down to −40 °C without freezing or phase separation. Its fluid path materials comply with USP Class VI and FDA 21 CFR Part 11 guidelines for indirect contact with pharmaceutical process streams. All thermal control functions support audit-trail-enabled operation when integrated with validated LIMS or SCADA systems. The unit conforms to IEC 61000-6-3 (EMC) and IEC 61010-1 (safety), and is CE-marked for use in EU laboratories. Optional IQ/OQ documentation packages are available to support GMP facility qualification per Annex 15 and WHO TRS 986 requirements.

Software & Data Management

The HLD-100 features an embedded 7-inch capacitive touchscreen HMI with real-time graphing, multi-segment programmable ramp/soak profiles, and configurable alarm thresholds (e.g., flow loss, overtemperature, low level). It supports RS485 Modbus RTU and Ethernet TCP/IP interfaces for integration into centralized lab automation platforms. Logged temperature, flow, and power data are timestamped and exportable in CSV format with ISO 8601-compliant timestamps. When connected to Titan’s optional LabLink™ software suite, users gain remote monitoring, electronic signature support, and 21 CFR Part 11-compliant audit trails—including user action logging, parameter change history, and system event records—for regulated environments.

Applications

• Controlled-temperature reaction calorimetry (RC1, EasyMax) and jacketed glass reactor systems
• Thermal cycling of battery cells and EV power electronics during environmental stress screening
• Stability testing of biologics and small-molecule APIs per ICH Q1A–Q1E guidelines
• Dynamic mechanical analysis (DMA) and differential scanning calorimetry (DSC) auxiliary temperature control
• Material testing under extreme thermal conditions—e.g., elastomer hysteresis, composite curing kinetics, and adhesive bond strength evaluation
• Calibration of infrared cameras, pyrometers, and other non-contact temperature sensors

FAQ

What heat transfer fluids are recommended for operation below −20 °C?
Ethylene glycol/water (30:70 v/v) or propylene glycol/water (40:60 v/v) mixtures are validated for use down to −40 °C. Silicone oils (e.g., Dow Corning® 200 Fluid 50 cSt) are required above 100 °C and fully compatible across the entire range.
Does the HLD-100 support external temperature feedback from a process sensor?
Yes—via optional PT100 input (2-/3-/4-wire), enabling cascade control where the chiller regulates based on actual process temperature rather than bath setpoint.
Is the unit suitable for cleanroom installation?
The air-cooled design minimizes particulate generation, and the sealed fluid reservoir meets ISO 14644-1 Class 8 requirements when installed with appropriate filtration; optional HEPA-filtered intake kits are available.
Can multiple HLD-100 units be synchronized for coordinated thermal control?
Yes—using Titan’s Master-Slave protocol over Modbus TCP, up to 8 units can share a common temperature program and fault-handling logic for large-scale thermal arrays.
What maintenance intervals are recommended for continuous 24/7 operation?
Compressor oil and refrigerant charge verification every 24 months; glycol concentration and pH testing every 6 months; filter replacement every 12 months—documented in the included Preventive Maintenance Logbook.