Sartorius QUINTIX224-1CN Advanced Analytical Balance

Overview

The Sartorius QUINTIX224-1CN is a high-precision analytical balance engineered for demanding laboratory environments where trace-level mass measurement, regulatory compliance, and operational reproducibility are non-negotiable. Built on Sartorius’ decades-long heritage in metrology, this 220 g / 0.1 mg balance employs electromagnetic force compensation (EMFC) technology—ensuring stable, drift-free measurements under variable thermal conditions. Its core architecture integrates temperature-compensated load cell design, draft shield compatibility, and real-time environmental monitoring to minimize uncertainty contributions from air buoyancy, static charge, or mechanical vibration. Designed for routine QC testing, formulation development, reference standard preparation, and method validation in pharmaceutical, chemical, and academic laboratories, the QUINTIX224-1CN meets the metrological requirements of ISO 9001, ISO/IEC 17025, and pharmacopeial standards including USP and EP 2.1.1.

Key Features

• isoCAL® Fully Automatic Internal Calibration: Temperature- and time-triggered self-calibration ensures continuous traceability without manual intervention; all calibration events—including date, time, ambient temperature, and deviation values—are logged with timestamp and user ID for audit readiness.
• 5.7-inch Capacitive Touchscreen Interface: Intuitive icon-driven navigation with context-sensitive prompts eliminates reliance on manuals; supports multi-language operation (English, German, French, Spanish, Chinese, Japanese) and customizable home screen layouts.
• Built-in Application Suite: Pre-installed workflows include Formulation (batch component weighing with cumulative total tracking), Statistics (mean, SD, RSD, min/max across up to 99 samples), Checkweighing (user-defined tolerance bands with visual/audible alerts), Density Determination (solid/liquid mode with integrated density kit support), Percentage Weighing, Piece Counting, and Peak Hold for dynamic or obstructed weighing scenarios.
• GLP/GMP-Compliant Data Integrity: All measurements, calibrations, and application logs are stored with immutable metadata (operator, timestamp, instrument ID, environment parameters); exportable via USB in CSV or TXT format with optional PDF report generation.
• Robust Mechanical Design: Stainless steel weighing pan (Ø90 mm), reinforced draft shield mounting, and shock-absorbing base reduce sensitivity to floor vibrations and air currents; IP54-rated enclosure protects internal electronics from dust and incidental splashes.

Sample Compatibility & Compliance

The QUINTIX224-1CN accommodates standard analytical sample containers—including weighing boats, crucibles, volumetric flasks, and vials—within its 209 mm tall weighing chamber. Its 90 mm pan diameter and optimized chamber geometry allow unobstructed access while maintaining aerodynamic stability during rapid stabilization (<3 seconds typical response time). The balance complies with key international standards governing analytical instrumentation: USP for repeatability and accuracy verification, ASTM E898 for balance performance evaluation, and ISO 17025 clause 6.4.4 for equipment suitability assessment. Full traceability documentation—including factory calibration certificate (NIST-traceable), EC Declaration of Conformity, and IQ/OQ protocol templates—is supplied with each unit.

Software & Data Management

Data transfer is streamlined via native USB interface: no proprietary drivers or configuration required. When connected to a Windows PC, the balance appears as a HID-compliant device—enabling direct entry into Excel, LabWare LIMS, or custom SQL databases using standard keyboard emulation. All data exports include embedded metadata fields (e.g., “Operator=LAB-07”, “Calibrated=2024-05-12T08:22:15Z”, “Temp=22.3°C”). For regulated environments, optional Sartorius LabX™ software provides 21 CFR Part 11 compliance with electronic signatures, role-based access control, and full audit trail management—including modification history of calibration parameters and application settings.

Applications

• Pharmaceutical: Active pharmaceutical ingredient (API) dispensing, reference standard preparation, dissolution testing sample quantification, and content uniformity analysis per USP .
• Chemistry: Gravimetric titration reagent preparation, catalyst loading in catalysis research, and stoichiometric ratio verification in synthetic pathways.
• Materials Science: Coating thickness calculation via mass-per-area conversion, nanoparticle yield determination, and polymer additive dosing.
• Food & Agriculture: Nutrient composition analysis, pesticide residue quantification, and moisture content determination by loss-on-drying protocols.
• Academic Research: Teaching labs requiring ISO-certified instrumentation for metrology education, inter-laboratory comparison studies, and thesis-level quantitative analysis.

FAQ

What does “isoCAL®” mean and how often does it activate?
isoCAL® is Sartorius’ patented internal calibration system that triggers automatically when temperature changes exceed ±1.5 °C or at user-defined intervals (e.g., every 2 hours). Each event is fully documented in the internal log.
Is the QUINTIX224-1CN compliant with 21 CFR Part 11?
Yes—when used with LabX™ software, it supports electronic signatures, audit trails, and role-based permissions required for FDA-regulated environments.
Can I connect this balance to a network or LIMS?
Yes—via optional Ethernet module or RS232 interface; LabX enables secure TCP/IP communication with enterprise LIMS and ELN systems.
Does it support density measurement of irregular solids?
Yes—using the built-in density application and optional Sartorius density kit (including sinker, thermometer, and liquid reservoir), both solid and liquid density can be determined per ISO 1183 and ASTM D792.
What environmental conditions affect its performance?
Optimal operation requires stable ambient temperature (10–30 °C), relative humidity <80% RH non-condensing, and placement on a vibration-isolated surface away from HVAC vents or foot traffic.