ZiQi ZQ-FD-80 -86°C Benchtop Laboratory Freeze Dryer
| Brand | ZiQi |
|---|---|
| Origin | Shanghai, China |
| Manufacturer Type | Direct Manufacturer |
| Instrument Type | Standard Shelf-Type Freeze Dryer |
| Application Scope | Laboratory Use Only |
| Lyophilization Area | 0.12 m² |
| Ultimate Vacuum | < 5 Pa (at no-load) |
| Condenser Temperature | < -86°C (at no-load) |
| Ice Capacity | 3–4 kg/24 h |
| Main Unit Dimensions | 600 × 500 × 900 mm |
| Power Consumption | 970 W |
| Net Weight | 41 kg |
Overview
The ZiQi ZQ-FD-80 is a compact, high-performance benchtop freeze dryer engineered for reliable lyophilization in research laboratories, quality control environments, and small-scale pilot production. Based on the fundamental principles of sublimation under deep vacuum and cryogenic condensation, this system removes water from heat-sensitive biological, pharmaceutical, and chemical samples while preserving structural integrity, enzymatic activity, and immunogenicity. Operating at a condenser temperature of ≤ –86°C and achieving an ultimate vacuum of < 5 Pa (no-load), the ZQ-FD-80 ensures efficient primary drying across diverse sample matrices—including aqueous solutions, suspensions, and viscous formulations—without thermal degradation. Its integrated design eliminates external flanges and minimizes leak paths, supporting reproducible process execution in compliance with foundational Good Laboratory Practice (GLP) requirements.
Key Features
- Monolithic stainless steel construction for the condenser chamber and work surface—corrosion-resistant, non-porous, and compliant with routine cleaning validation protocols.
- Proprietary gas-flow optimization technology ensures uniform ice deposition across the entire condenser surface, maximizing capture efficiency and minimizing re-volatilization during extended drying cycles.
- Self-designed stainless steel pneumatic valve for controlled chamber venting and defrosting—leak-tight, chemically inert, and rated for repeated sterilization-grade operation.
- Large-diameter condenser port with no internal coil obstruction—enables direct pre-freezing of samples on shelves, eliminating dependency on external ultra-low temperature freezers.
- Integrated SH-HPSC-I modular controller paired with a high-resolution industrial touchscreen interface—supports real-time monitoring of critical parameters including shelf temperature, condenser temperature, chamber pressure, and time-stamped event logging.
- Intelligent vacuum pump protection logic: automatic pump activation only after condenser reaches target temperature (< –70°C), significantly extending pump service life and reducing oil contamination risk.
- Equipped with a high-efficiency Secop (Germany) compressor and a robust dual-stage rotary vane vacuum pump (2 L/min displacement, with integrated oil mist filter).
Sample Compatibility & Compliance
The ZQ-FD-80 accommodates standard laboratory formats including 200 mm stainless steel trays (4-layer configuration, expandable to 6 layers), 180 mm trays (3-layer), and optional vial racks for 12 mm, 16 mm, and 22 mm diameter serum vials. It supports lyophilization of proteins, vaccines, monoclonal antibodies, microbial cultures, plant extracts, and diagnostic reagents. All wetted surfaces contact only 304 stainless steel or food-grade silicone elastomers—fully compatible with ISO 13485-aligned material traceability and USP lyophilization guidance. While not certified for GMP manufacturing, its data integrity architecture—including timestamped parameter curves and exportable CSV logs—meets GLP documentation expectations and facilitates audit readiness per FDA 21 CFR Part 11 (when used with validated software workflows).
Software & Data Management
The embedded controller records and displays three synchronized real-time curves: condenser temperature, chamber pressure, and (optional probe-based) sample temperature. All data points are time-stamped with millisecond resolution and stored internally for up to 30 days. Export is supported via USB 2.0 to standard CSV format, enabling post-processing in MATLAB, Python (Pandas), or Excel. No cloud connectivity or remote access is implemented—ensuring full data sovereignty and alignment with institutional IT security policies. Audit trails include operator ID (if enabled), method name, start/stop timestamps, and deviation alerts (e.g., vacuum excursion > 10 Pa for >30 s).
Applications
- Stabilization of thermolabile biologics prior to long-term storage or transport.
- Preparation of calibration standards and reference materials for analytical chemistry labs.
- Drying of microbial cultures for strain banking and preservation.
- Processing of botanical extracts and nutraceuticals without solvent residue or oxidation.
- Lyophilization of diagnostic assay components—including ELISA plates, lateral flow reagents, and PCR master mixes.
- Supporting formulation development studies where residual moisture content must be controlled to <1.5% w/w.
FAQ
What is the maximum sample volume capacity for the ZQ-FD-80A model?
Up to 1.2 L (at 10 mm fill depth) using four 200 mm trays.
Does the system support shelf temperature control during drying?
No—this is a non-heated shelf model; temperature control is limited to condenser and chamber pressure regulation.
Can the ZQ-FD-80 meet ASTM F2477-20 requirements for lyophilizer qualification?
It provides the foundational hardware and data logging capability required for Installation Qualification (IQ) and Operational Qualification (OQ); Performance Qualification (PQ) must be conducted per user-defined protocols.
Is the vacuum pump included in the standard configuration?
Yes—a 2 L/min oil-sealed rotary vane pump with oil mist filter and vacuum oil is supplied as part of the base package.
What maintenance intervals are recommended for the Secop compressor?
Compressor oil level and refrigerant charge should be verified annually; full service by authorized technicians is recommended every 36 months or after 6,000 operational hours.
